HitPredict

Interactor 1: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	25416956, 29892012, unassigned3799
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008154 - actin polymerization or depolymerization GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 513
+	Hs
		896578 VASP_HUMAN (1-380): 1.44e-91: 281: 100.00		ABI1_HUMAN (1-513): 1.58e-95: 300: 60.43
+	Hs
		1295191 HOME1_HUMAN (1-182): 5.63e-51: 175: 23.24		ABI1_HUMAN (1-513): 1.58e-95: 300: 60.43
+	Hs
		1316711 HOME3_HUMAN (3-294): 6.79e-48: 168: 18.54		ABI1_HUMAN (1-513): 1.58e-95: 300: 60.43
+	Hs
		1449319 HOME3_HUMAN (3-294): 6.79e-48: 168: 18.54		ABI2_HUMAN (1-513): 2.17e-91: 290: 100.00
+	Mm
		1298233 MINK1_MOUSE (88-364): 1.96e-21: 98.6: 13.62		ABI1_MOUSE (1-513): 1.19e-98: 307: 60.43
+	Hs
		1316675 ENAH_HUMAN (109-379): 3.93e-23: 102: 30.06		ABI1_HUMAN (1-513): 1.58e-95: 300: 60.43
+	Dm
		1346044 ENA_DROME (2-235): 1.22e-41: 158: 36.33		Q9Y0S9_DROME (1-507): 3.22e-72: 238: 34.91
+	Hs
		1331368 ENAH_HUMAN (109-379): 3.93e-23: 102: 30.06		ABI2_HUMAN (1-513): 2.17e-91: 290: 100.00
+	Hs
		896505 VASP_HUMAN (1-380): 1.44e-91: 281: 100.00		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		896651 VASP_HUMAN (1-380): 1.44e-91: 281: 100.00		ABI3_HUMAN (262-507): 4.43e-16: 81.7: 23.17
+	Hs
		215909 VASP_HUMAN (1-380): 1.44e-91: 281: 100.00		SYNJ1_HUMAN (83-381): 1.45e-09: 62.9: 12.42
+	Hs
		1454441 EVL_HUMAN (1-375): 2.07e-60: 202: 43.68		ABI3_HUMAN (262-507): 4.43e-16: 81.7: 23.17
+	Hs
		1449301 HOME2_HUMAN (1-162): 1.42e-59: 198: 23.64		ABI3_HUMAN (262-507): 4.43e-16: 81.7: 23.17
+	Hs
		1295224 HOME1_HUMAN (1-182): 5.63e-51: 175: 23.24		ABI3_HUMAN (262-507): 4.43e-16: 81.7: 23.17
+	Hs
		1449321 HOME3_HUMAN (3-294): 6.79e-48: 168: 18.54		ABI3_HUMAN (262-507): 4.43e-16: 81.7: 23.17
+	Mm
		1221239 DYN3_MOUSE (15-212): 1.15e-38: 149: 20.49		GRB2_MOUSE (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		988036 DYN3_HUMAN (15-212): 2.78e-38: 148: 20.98		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		987773 MINK1_HUMAN (88-364): 7.53e-36: 141: 15.90		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		571698 PCLO_HUMAN (116-283): 2.52e-09: 61.2: 16.57		HCLS1_HUMAN (271-508): 6.97e-30: 124: 19.86
+	Hs
		1331373 ENAH_HUMAN (109-379): 3.93e-23: 102: 30.06		ABI3_HUMAN (262-507): 4.43e-16: 81.7: 23.17