Interactor 1: PARC (P72525)
DNA topoisomerase 4 subunit A (EC 5.6.2.2) (Topoisomerase IV subunit A)
Gene: PARC

Interactor 2: PARE (Q59961)
DNA topoisomerase 4 subunit B (EC 5.6.2.2) (Topoisomerase IV subunit B)
Gene: PARE

Species: Streptococcus pneumoniae TIGR4

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19448616
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_gyraseB~DNA_topoisoIV, DNA_gyraseB_C~DNA_topoisoIV, DNA_topoisoIV~Toprim
Common GO terms GO:0003677 - DNA binding
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005694 - chromosome
GO:0006265 - DNA topological change
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 823
Sp

1 647
+ At
+ Mp
+ Ec
+ Hs
+ Hs
+ Dm
+ Zm
+ Hp
+ Ec
+ Sc
+ Mp
+ Mp

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Last updated: 15 Jul 2024