Protein: VPS25
Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25)

Gene: VPS25
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q9BRG1

Gene Ontology (top 5):
GO:0000814 - ESCRT II complex
GO:0005198 - structural molecule activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1392616

SNF8
Vacuolar-sorting protein SNF8

13

3

Small-scale

0.984

High

1290887

VPS36
Vacuolar protein-sorting-associated protein 36

10

7

Small-scale

0.975

High

1391143

CHMP6
Charged multivesicular body protein 6

9

8

Small-scale

0.756

High

1411114

VPS25
Vacuolar protein-sorting-associated protein 25

1

1

Small-scale

0.680

High

1307703

CRLF3
Cytokine receptor-like factor 3

4

0

High-throughput

0.675

High

572166

TRI27
Zinc finger protein RFP

4

0

High-throughput

0.668

High

1411127

VPS28
Vacuolar protein sorting-associated protein 28 homolog

3

1

Small-scale

0.656

High

1369524

KIFA3
Kinesin-associated protein 3

2

0

High-throughput

0.602

High

1048980

REL
Proto-oncogene c-Rel

2

0

High-throughput

0.601

High

283541

TAD2A
Transcriptional adapter 2-alpha

2

0

High-throughput

0.580

High

1256420

SEP14
Septin-14

2

0

High-throughput

0.580

High

1287712

LPP60
60 kDa lysophospholipase

2

0

High-throughput

0.580

High

1409544

B9D2
B9 domain-containing protein 2

2

0

High-throughput

0.580

High

1411117

SDCB2
Syntenin-2

2

0

High-throughput

0.580

High

1411122

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1411124

SPG21
Maspardin

2

0

High-throughput

0.580

High

1407447

TS101
Tumor susceptibility gene 101 protein

1

1

High-throughput

0.536

High

221175

SPY2
Protein sprouty homolog 2

1

0

Small-scale

0.529

High

1392537

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.518

High

1410983

RHXF2
Rhox homeobox family member 2

1

0

High-throughput

0.518

High

1411121

LT4R2
Leukotriene B4 receptor 2

1

0

High-throughput

0.518

High

60630

TESP1
Protein TESPA1

1

0

High-throughput

0.513

High

614728

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.513

High

854261

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

1025224

HXC5
Homeobox protein Hox-C5

1

0

High-throughput

0.513

High

1115961

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.513

High

1143010

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

1291979

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

1364559

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.513

High

1366805

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

0

High-throughput

0.513

High

1397761

CANB2
Calcineurin subunit B type 2

1

0

High-throughput

0.513

High

1407038

SNAG
Gamma-soluble NSF attachment protein

1

0

High-throughput

0.513

High

1411115

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.513

High

1411118

VP37B
Vacuolar protein sorting-associated protein 37B

1

0

High-throughput

0.513

High

1411123

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

1411126

FBX2
F-box only protein 2

1

0

High-throughput

0.513

High

508527

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

1389980

MB12A
Multivesicular body subunit 12A

1

1

High-throughput

0.479

High

791669

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

589540

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

696346

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

769019

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

941535

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.458

High

1397368

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1411125

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

117805

M0QZK6
Multivesicular body subunit 12A

1

1

High-throughput

0.407

High

1322136

SYCE1
Synaptonemal complex central element protein 1

2

0

High-throughput

0.316

High

1411120

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.316

High

1272141

BEND5
BEN domain-containing protein 5

1

0

High-throughput

0.299

High

1411119

GPR35
G-protein coupled receptor 35

1

0

High-throughput

0.282

High

1203517

S45A4
Solute carrier family 45 member 4

1

0

High-throughput

0.279

Low

1411116

CF062
Uncharacterized protein C6orf62

1

0

High-throughput

0.279

Low

994950

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025