Protein: VPS36
Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36)

Gene: VPS36
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q86VN1

Gene Ontology (top 5):
GO:0000814 - ESCRT II complex
GO:0005634 - nucleus
GO:0005764 - lysosome
GO:0005768 - endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1290887

VPS25
Vacuolar protein-sorting-associated protein 25

10

7

Small-scale

0.975

High

1290881

SNF8
Vacuolar-sorting protein SNF8

10

4

Small-scale

0.974

High

508226

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

6

Small-scale

0.862

High

507257

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

6

High-throughput

0.811

High

1290886

TS101
Tumor susceptibility gene 101 protein

3

6

Small-scale

0.641

High

1290875

VPS36
Vacuolar protein-sorting-associated protein 36

1

7

Small-scale

0.621

High

242166

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.618

High

1290880

CHMP6
Charged multivesicular body protein 6

2

11

Small-scale

0.614

High

1153186

HERC1
Probable E3 ubiquitin-protein ligase HERC1

2

0

High-throughput

0.602

High

931554

RD23A
UV excision repair protein RAD23 homolog A

1

1

High-throughput

0.575

High

1290893

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

4

Small-scale

0.571

High

1290891

CENPM
Centromere protein M

1

1

High-throughput

0.536

High

1290879

CUL5
Cullin-5

1

0

High-throughput

0.513

High

1290885

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1290892

FBX2
F-box only protein 2

1

0

High-throughput

0.513

High

1290883

RILP
Rab-interacting lysosomal protein

1

1

Small-scale

0.501

High

1290888

CF062
Uncharacterized protein C6orf62

1

1

High-throughput

0.489

High

331109

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.479

High

589067

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

695856

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

1219288

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

Small-scale

0.479

High

221151

SPY2
Protein sprouty homolog 2

1

0

Small-scale

0.460

High

791501

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

1140501

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1290877

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1290889

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1290890

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

768567

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

517292

ZTRF1
Zinc finger TRAF-type-containing protein 1

1

0

High-throughput

0.426

High

1290876

S2541
Mitochondrial carrier protein SCaMC-3L

3

0

High-throughput

0.347

High

664984

ERD21
ER lumen protein-retaining receptor 1

2

0

High-throughput

0.328

High

596499

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

1290882

ARL5B
ADP-ribosylation factor-like protein 5B

1

0

High-throughput

0.279

Low

1164451

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

1290878

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low

1038197

GCNT1
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

1

0

Small-scale

0.238

Low

539718

ACHB
Acetylcholine receptor subunit beta

1

0

High-throughput

0.232

Low

926799

VMAT1
Chromaffin granule amine transporter

1

0

High-throughput

0.232

Low

1185984

SOAT
Sodium-dependent organic anion transporter

1

0

High-throughput

0.232

Low

1290884

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025