Protein: MTNB
Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP)

Gene: MTNB, APIP
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q96GX9

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0008270 - zinc ion binding
GO:0019509 - L-methionine salvage from methylthioadenosine

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1392534

MTNB
Methylthioribulose-1-phosphate dehydratase

6

3

High-throughput

0.959

High

1348422

LNX1
E3 ubiquitin-protein ligase LNX

5

0

High-throughput

0.691

High

1256875

NUD18
8-oxo-dGDP phosphatase NUDT18

3

0

High-throughput

0.643

High

1348708

UBA3
NEDD8-activating enzyme E1 catalytic subunit

3

0

High-throughput

0.638

High

1392542

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

3

0

High-throughput

0.638

High

1392545

T22D4
TSC22 domain family protein 4

2

0

High-throughput

0.616

High

1382744

ISOC2
Isochorismatase domain-containing protein 2

2

0

High-throughput

0.602

High

164624

TNPO2
Transportin-2

2

0

High-throughput

0.601

High

1392535

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.601

High

1392544

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

2

0

High-throughput

0.580

High

161739

APAF
Apoptotic protease-activating factor 1

1

0

Small-scale

0.549

High

140401

SDCB1
Syntenin-1

1

0

High-throughput

0.549

High

552670

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.549

High

664394

ZBT25
Zinc finger and BTB domain-containing protein 25

1

0

High-throughput

0.549

High

680982

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.549

High

992301

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.549

High

1165402

Q17RL8
HCG2004980, isoform CRA_e

2

1

High-throughput

0.544

High

1392538

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.536

High

652388

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

1062284

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.536

High

1260561

PDZD4
PDZ domain-containing protein 4

2

1

High-throughput

0.526

High

474896

VIME
Vimentin

1

0

High-throughput

0.518

High

1392537

VPS25
Vacuolar protein-sorting-associated protein 25

1

0

High-throughput

0.518

High

276617

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.513

High

941828

ARL4C
ADP-ribosylation factor-like protein 4C

1

0

High-throughput

0.513

High

1213808

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.513

High

1338060

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.513

High

1392536

GSDMA
Gasdermin-A

1

0

High-throughput

0.513

High

1392539

RNAS7
Ribonuclease 7

1

0

High-throughput

0.513

High

1392541

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.513

High

1392543

IL37
Interleukin-37

1

0

High-throughput

0.513

High

1160547

SMN
Survival motor neuron protein

1

0

High-throughput

0.493

High

786776

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

Small-scale

0.486

High

1090850

TRAF2
TNF receptor-associated factor 2

1

1

High-throughput

0.479

High

1093917

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.479

High

970920

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1113988

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1198631

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

1236034

HPHL1
Ferroxidase HEPHL1

3

0

High-throughput

0.347

High

1286403

LYG2
Lysozyme g-like protein 2

3

0

High-throughput

0.347

High

1286458

DSG4
Desmoglein-4

3

0

High-throughput

0.347

High

1392540

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.316

High

1315378

CF206
Cilia- and flagella-associated protein 206

1

0

High-throughput

0.299

High

516713

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

0

High-throughput

0.288

High

473714

ITA5
Integrin alpha-5

1

0

High-throughput

0.279

Low

892130

KLK7
Kallikrein-7

1

0

High-throughput

0.279

Low

1248722

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

1309609

SPA12
Serpin A12

1

0

High-throughput

0.279

Low

1358552

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025