Protein: LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3 (Synaptic adhesion-like molecule 4)

Gene: LRFN3
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q9BTN0

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0030424 - axon
GO:0030425 - dendrite
GO:0048787 - presynaptic active zone membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1286889

TM11B
Transmembrane protease serine 11B

2

10

High-throughput

0.811

High

1288330

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

2

18

High-throughput

0.811

High

1413592

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

2

1

High-throughput

0.811

High

944928

TMPS3
Transmembrane protease serine 3

2

11

High-throughput

0.726

High

168448

NCTR3
Natural cytotoxicity triggering receptor 3

1

1

High-throughput

0.691

High

351798

LGI1
Leucine-rich glioma-inactivated protein 1

1

15

High-throughput

0.691

High

519657

LYAG
Lysosomal alpha-glucosidase

1

3

High-throughput

0.691

High

568090

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

6

High-throughput

0.691

High

1164078

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

11

High-throughput

0.691

High

1363132

CLC2B
C-type lectin domain family 2 member B

1

20

High-throughput

0.691

High

1413587

CRLF2
Cytokine receptor-like factor 2

1

6

High-throughput

0.691

High

1198748

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.679

High

1116290

PTC1
Protein patched homolog 1

3

2

High-throughput

0.667

High

1360198

5HT3C
5-hydroxytryptamine receptor 3C

3

2

High-throughput

0.667

High

561386

TDGF1
Protein Cripto

2

2

High-throughput

0.628

High

567969

PRG2
Bone marrow proteoglycan

1

3

High-throughput

0.618

High

935790

MFAP4
Microfibril-associated glycoprotein 4

1

3

High-throughput

0.618

High

1177874

CL12B
C-type lectin domain family 12 member B

1

15

High-throughput

0.618

High

1225866

WDR25
WD repeat-containing protein 25

1

2

High-throughput

0.618

High

1248792

LYZL1
Lysozyme-like protein 1

1

2

High-throughput

0.618

High

1413594

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

13

High-throughput

0.618

High

380346

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

6

High-throughput

0.618

High

520984

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

6

High-throughput

0.618

High

705986

CD1B
T-cell surface glycoprotein CD1b

1

9

High-throughput

0.618

High

1143782

PON2
Serum paraoxonase/arylesterase 2

2

4

High-throughput

0.611

High

1084065

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

3

1

High-throughput

0.609

High

1248576

LYPD4
Ly6/PLAUR domain-containing protein 4

2

0

High-throughput

0.602

High

1413591

FBX2
F-box only protein 2

2

13

High-throughput

0.601

High

749382

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

2

High-throughput

0.575

High

1413590

S17A5
Sialin

1

2

High-throughput

0.575

High

1413597

FLVC1
Choline/ethanolamine transporter FLVCR1

1

6

High-throughput

0.575

High

154875

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

18

High-throughput

0.553

High

1359232

CA054
Uncharacterized protein C1orf54

2

4

High-throughput

0.549

High

328728

VAMP5
Vesicle-associated membrane protein 5

1

1

High-throughput

0.536

High

341355

ECEL1
Endothelin-converting enzyme-like 1

1

1

High-throughput

0.536

High

506900

CFC1
Cryptic protein

1

2

High-throughput

0.536

High

1251794

S39A5
Zinc transporter ZIP5

1

5

High-throughput

0.536

High

1352083

TS1R2
Taste receptor type 1 member 2

1

2

High-throughput

0.536

High

1382049

T106A
Transmembrane protein 106A

1

5

High-throughput

0.536

High

1384590

ESPB1
Epididymal sperm-binding protein 1

1

2

High-throughput

0.536

High

1413593

TNF18
Tumor necrosis factor ligand superfamily member 18

1

1

High-throughput

0.536

High

889935

VEGFB
Vascular endothelial growth factor B

2

1

High-throughput

0.521

High

49816

CLRN2
Clarin-2

1

2

High-throughput

0.489

High

388738

C1QB
Complement C1q subcomponent subunit B

1

4

High-throughput

0.489

High

548105

PSPC
Surfactant protein C

1

5

High-throughput

0.489

High

948018

DEF1
Neutrophil defensin 1

1

2

High-throughput

0.489

High

1101412

SG2A2
Mammaglobin-A

1

3

High-throughput

0.489

High

1245915

BRID5
BRICHOS domain-containing protein 5

1

4

High-throughput

0.489

High

1369055

GGH
Gamma-glutamyl hydrolase

1

2

High-throughput

0.489

High

1396508

LCFC1
Sperm-egg fusion protein LLCFC1

1

1

High-throughput

0.489

High

1413584

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

4

High-throughput

0.489

High

1413589

SDF2L
Stromal cell-derived factor 2-like protein 1

1

3

High-throughput

0.489

High

1413595

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.479

High

1413596

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

1

High-throughput

0.479

High

1413588

ANKH
Mineralization regulator ANKH

1

2

High-throughput

0.445

High

1413585

GL8D2
Glycosyltransferase 8 domain-containing protein 2

1

1

High-throughput

0.437

High

170938

CLGN
Calmegin

1

12

High-throughput

0.407

High

1413586

DPEP2
Dipeptidase 2

3

0

High-throughput

0.347

High

1034812

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025