Protein: LYRM4
LYR motif-containing protein 4

Gene: LYRM4
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9HD34

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0016226 - iron-sulfur cluster assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

156506

ACPM
Acyl carrier protein, mitochondrial

4

2

High-throughput

0.895

High

1439634

NFS1
Cysteine desulfurase

3

2

Small-scale

0.870

High

1431148

ISCU
Iron-sulfur cluster assembly enzyme ISCU

3

2

Small-scale

0.656

High

329984

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

3

0

High-throughput

0.638

High

1199704

KLH22
Kelch-like protein 22

2

1

High-throughput

0.628

High

1310433

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

0

High-throughput

0.585

High

282095

MPPB
Mitochondrial-processing peptidase subunit beta

2

3

High-throughput

0.584

High

1083764

MPPA
Mitochondrial-processing peptidase subunit alpha

2

3

High-throughput

0.584

High

279927

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1058293

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

High-throughput

0.559

High

1162568

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

1366783

NECT2
Nectin-2

1

0

High-throughput

0.518

High

647662

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

High-throughput

0.513

High

682621

S100P
Protein S100-P

1

0

High-throughput

0.513

High

1380913

RAB24
Ras-related protein Rab-24

1

0

High-throughput

0.513

High

229572

NRDC
Nardilysin

1

4

High-throughput

0.479

High

287386

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.479

High

575204

IDE
Insulin-degrading enzyme

1

4

High-throughput

0.479

High

856392

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

1092657

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.479

High

1117851

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

1159362

FRDA
Frataxin, mitochondrial

1

1

High-throughput

0.479

High

1273002

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

1381734

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1439631

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

61647

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66303

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

194358

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

243003

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

351005

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

532987

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

554847

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

828972

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

852040

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882904

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

937922

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

1024198

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1048710

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1114363

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1142675

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1234536

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1293602

HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial

1

0

High-throughput

0.458

High

1388281

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1388418

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1401629

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

1412444

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1416552

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1418892

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1435793

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1436094

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1439628

LYRM4
LYR motif-containing protein 4

1

0

High-throughput

0.458

High

1439629

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1439630

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1439633

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1439635

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

1121531

KEAP1
Kelch-like ECH-associated protein 1

1

1

High-throughput

0.407

High

409614

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

3

0

High-throughput

0.347

High

1402863

GPX7
Glutathione peroxidase 7

2

0

High-throughput

0.328

High

1090371

EPS8
Epidermal growth factor receptor kinase substrate 8

1

0

High-throughput

0.279

Low

1158829

CART

1

0

High-throughput

0.279

Low

1314296

EFC13
EF-hand calcium-binding domain-containing protein 13

1

0

High-throughput

0.279

Low

1439632

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

314962

DDAH1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

1

0

High-throughput

0.249

Low

377734

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1015811

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

1193509

CDNF
Cerebral dopamine neurotrophic factor

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025