Protein: L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) (Duranin)

Gene: L2HDH, L2HGDH
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9H9P8

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006103 - 2-oxoglutarate metabolic process
GO:0016020 - membrane
GO:0044281 - small molecule metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

611338

TGM1
Protein-glutamine gamma-glutamyltransferase K

3

0

High-throughput

0.638

High

198471

KLK10
Kallikrein-10

3

3

High-throughput

0.609

High

428635

INVO
Involucrin

3

1

High-throughput

0.609

High

72348

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

3

1

High-throughput

0.585

High

639941

ITB8
Integrin beta-8

2

1

High-throughput

0.574

High

729234

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

1

High-throughput

0.536

High

1219009

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1334395

NPS3A
Protein NipSnap homolog 3A

1

1

High-throughput

0.536

High

1334396

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

1

High-throughput

0.536

High

1334397

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

172229

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.513

High

488388

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

815445

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

968921

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1048381

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

1150169

ATLA3
Atlastin-3

1

0

High-throughput

0.513

High

1253030

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

66443

A2ML1
Alpha-2-macroglobulin-like protein 1

2

1

High-throughput

0.504

High

245418

RAMP3
Receptor activity-modifying protein 3

1

2

High-throughput

0.489

High

546889

PPAP
Prostatic acid phosphatase

1

1

High-throughput

0.489

High

1334398

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

228736

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

967975

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

1042567

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1086794

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

2

High-throughput

0.479

High

1269649

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

258530

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

719156

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

921730

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

1126356

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.458

High

780126

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

1043231

CUL4A
Cullin-4A

1

4

High-throughput

0.437

High

1171760

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1331320

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1334394

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.437

High

245841

CATL2
Cathepsin L2

3

0

High-throughput

0.347

High

945739

NGAL
Neutrophil gelatinase-associated lipocalin

3

0

High-throughput

0.347

High

179263

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

282250

SEGN
Secretagogin

1

0

High-throughput

0.279

Low

470562

H2A1
Histone H2A type 1

1

0

High-throughput

0.279

Low

614230

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.279

Low

702414

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

820388

SPB4
Serpin B4

1

0

High-throughput

0.279

Low

1016546

HYAL1
Hyaluronidase-1

1

0

High-throughput

0.279

Low

1205556

TMM25
Transmembrane protein 25

1

0

High-throughput

0.279

Low

1313676

TBB2B
Tubulin beta-2B chain

1

0

High-throughput

0.279

Low

1327961

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.279

Low

572147

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.249

Low

1101297

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1243945

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1327104

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1327574

TOLIP
Toll-interacting protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024