Protein: BAX
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)

Gene: BAX
Organism: Homo sapiens
Interactions: 118
UniProt ID: Q07812

Gene Ontology (top 5):
GO:0001541 - ovarian follicle development
GO:0001764 - neuron migration
GO:0001777 - T cell homeostatic proliferation
GO:0001782 - B cell homeostasis
GO:0001783 - B cell apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

991994

B2CL1
Bcl-2-like protein 1

32

18

Small-scale

0.993

High

489401

BCL2
Apoptosis regulator Bcl-2

25

17

Small-scale

0.990

High

991993

BAX
Apoptosis regulator BAX

17

17

Small-scale

0.986

High

991995

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

12

16

Small-scale

0.979

High

992025

B2CL2
Bcl-2-like protein 2

7

17

Small-scale

0.965

High

206738

B2L11
Bcl-2-like protein 11

7

17

Small-scale

0.962

High

992002

BAK
Bcl-2 homologous antagonist/killer

6

17

Small-scale

0.935

High

879513

BID
BH3-interacting domain death agonist

3

10

Small-scale

0.865

High

992044

B2L10
Bcl-2-like protein 10

3

4

Small-scale

0.847

High

386598

P53
Cellular tumor antigen p53

2

9

Small-scale

0.806

High

992001

B2LA1
Bcl-2-related protein A1

2

16

Small-scale

0.783

High

992027

BAD
Bcl2-associated agonist of cell death

2

8

Small-scale

0.737

High

523693

XRCC6
X-ray repair cross-complementing protein 6

7

2

Small-scale

0.736

High

500778

CLUS
Clusterin

5

1

Small-scale

0.702

High

992043

B2L12
Bcl-2-like protein 12

4

2

Small-scale

0.699

High

992053

ASC
Apoptosis-associated speck-like protein containing a CARD

1

2

Small-scale

0.696

High

992055

SHLB1
Endophilin-B1

3

1

Small-scale

0.664

High

601226

VDAC1
Voltage-dependent anion-selective channel protein 1

3

8

Small-scale

0.646

High

991998

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

7

Small-scale

0.618

High

681807

AKT1
RAC-alpha serine/threonine-protein kinase

2

3

Small-scale

0.602

High

992048

UVRAG
UV radiation resistance-associated gene protein

2

0

Small-scale

0.595

High

992007

B2L15
Bcl-2-like protein 15

2

0

High-throughput

0.585

High

227260

PRKN
E3 ubiquitin-protein ligase parkin

2

7

Small-scale

0.584

High

252993

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

575403

EGR1
Early growth response protein 1

2

0

Small-scale

0.576

High

259278

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

1

Small-scale

0.573

High

358749

CRYAA
Alpha-crystallin A chain

1

6

Small-scale

0.561

High

359004

CRYAB
Alpha-crystallin B chain

1

6

Small-scale

0.561

High

646829

1433T
14-3-3 protein theta

1

4

Small-scale

0.561

High

983814

KPCZ
Protein kinase C zeta type

1

4

Small-scale

0.561

High

992036

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

2

Small-scale

0.561

High

992046

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.559

High

992032

FXL20
F-box/LRR-repeat protein 20

1

0

Small-scale

0.554

High

992016

HUNIN
Humanin

1

0

Small-scale

0.549

High

602903

KCNA3
Potassium voltage-gated channel subfamily A member 3

2

1

Small-scale

0.543

High

972181

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

8

High-throughput

0.541

High

835693

GSK3B
Glycogen synthase kinase-3 beta

1

9

Small-scale

0.536

High

976440

ERCC6
DNA excision repair protein ERCC-6

1

1

High-throughput

0.536

High

992004

EDRF1
Erythroid differentiation-related factor 1

1

1

High-throughput

0.536

High

992034

SPB12
Serpin B12

1

2

High-throughput

0.536

High

992042

WDR76
WD repeat-containing protein 76

1

2

High-throughput

0.536

High

518128

ADT1
ADP/ATP translocase 1

1

0

Small-scale

0.529

High

992000

IRF3
Interferon regulatory factor 3

1

1

Small-scale

0.527

High

992023

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

0

High-throughput

0.518

High

992051

LEF1
Lymphoid enhancer-binding factor 1

1

0

High-throughput

0.518

High

742247

SYUA
Alpha-synuclein

1

1

High-throughput

0.515

High

157732

GEMI2
Gem-associated protein 2

1

0

High-throughput

0.513

High

304541

PRS23
Serine protease 23

1

0

High-throughput

0.513

High

632706

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.513

High

836716

DNLI3
DNA ligase 3

1

0

High-throughput

0.513

High

992005

PPM1J
Protein phosphatase 1J

1

0

High-throughput

0.513

High

992017

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

992018

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

0

High-throughput

0.513

High

992037

ATAD5
ATPase family AAA domain-containing protein 5

1

0

High-throughput

0.513

High

992039

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

992054

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.513

High

992014

R144B
E3 ubiquitin-protein ligase RNF144B

1

0

Small-scale

0.512

High

265513

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

Small-scale

0.501

High

992038

PARK7
Parkinson disease protein 7

1

1

Small-scale

0.501

High

61758

BDP1
Transcription factor TFIIIB component B'' homolog

1

1

High-throughput

0.489

High

473056

BNIP5
Protein BNIP5

1

2

High-throughput

0.489

High

992019

NIN
Ninein

1

1

High-throughput

0.489

High

683292

1433B
14-3-3 protein beta/alpha

1

4

Small-scale

0.481

High

196599

ZBT24
Zinc finger and BTB domain-containing protein 24

1

0

Small-scale

0.480

High

324360

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.479

High

330663

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

8

Small-scale

0.479

High

499705

CH60
60 kDa heat shock protein, mitochondrial

1

7

Small-scale

0.479

High

524891

XRCC5
X-ray repair cross-complementing protein 5

1

2

Small-scale

0.479

High

572936

PRS6A
26S proteasome regulatory subunit 6A

1

2

Small-scale

0.479

High

683989

1433S
14-3-3 protein sigma

1

4

Small-scale

0.479

High

714197

HSP74
Heat shock 70 kDa protein 4

1

2

Small-scale

0.479

High

800758

MK08
Mitogen-activated protein kinase 8

1

13

Small-scale

0.479

High

808543

YAP1
Transcriptional coactivator YAP1

1

2

Small-scale

0.479

High

905851

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

11

High-throughput

0.479

High

908432

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

940817

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

957690

XIAP
E3 ubiquitin-protein ligase XIAP

1

1

Small-scale

0.479

High

969076

KPCE
Protein kinase C epsilon type

1

3

Small-scale

0.479

High

991996

EP300
Histone acetyltransferase p300

1

5

Small-scale

0.479

High

991999

TRI14
Tripartite motif-containing protein 14

1

3

High-throughput

0.479

High

992006

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

Small-scale

0.479

High

992008

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

992010

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

992011

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

2

Small-scale

0.479

High

992013

BOP
Protein Bop

1

6

Small-scale

0.479

High

992024

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

992030

MOAP1
Modulator of apoptosis 1

1

2

Small-scale

0.479

High

992031

GIMA5
GTPase IMAP family member 5

1

5

Small-scale

0.479

High

992033

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

Small-scale

0.479

High

992035

BBC3B
Bcl-2-binding component 3, isoforms 3/4

1

5

Small-scale

0.479

High

992040

EPAS1
Endothelial PAS domain-containing protein 1

1

5

Small-scale

0.479

High

992049

HDAC6
Histone deacetylase 6

1

1

Small-scale

0.479

High

992050

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

258434

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

390846

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

507960

FGFR1
Fibroblast growth factor receptor 1

1

0

Small-scale

0.458

High

651036

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

874863

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

907003

PRS8
26S proteasome regulatory subunit 8

1

0

Small-scale

0.458

High

991997

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

992009

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

992012

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

992021

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

992022

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

992026

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

992028

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.458

High

992041

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

992045

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

Small-scale

0.458

High

992047

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

992052

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

992015

VRK2
Serine/threonine-protein kinase VRK2

1

2

Small-scale

0.445

High

371220

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

1

Small-scale

0.437

High

992020

ARL10
ADP-ribosylation factor-like protein 10

1

1

High-throughput

0.437

High

789265

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

992003

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

720303

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

992029

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024