Protein: HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3)

Gene: HSDL1
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q3SXM5

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0043231 - intracellular membrane-bounded organelle
GO:0045111 - intermediate filament cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1187384

SCN3B
Sodium channel regulatory subunit beta-3

3

3

High-throughput

0.662

High

1053799

KDSR
3-ketodihydrosphingosine reductase

1

17

High-throughput

0.618

High

1187353

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

17

High-throughput

0.618

High

1187385

WWOX
WW domain-containing oxidoreductase

1

17

High-throughput

0.618

High

332647

LYPD3
Ly6/PLAUR domain-containing protein 3

3

1

High-throughput

0.609

High

252600

TSN2
Tetraspanin-2

3

5

High-throughput

0.604

High

1187365

PPTC7
Protein phosphatase PTC7 homolog

2

0

High-throughput

0.602

High

1187374

TRABD
TraB domain-containing protein

2

0

High-throughput

0.585

High

668997

FPR2
N-formyl peptide receptor 2

2

4

High-throughput

0.574

High

1187358

RN19B
E3 ubiquitin-protein ligase RNF19B

2

5

High-throughput

0.574

High

1187372

GPR21
Probable G-protein coupled receptor 21

2

1

High-throughput

0.574

High

1187388

MTCH2
Mitochondrial carrier homolog 2

2

4

High-throughput

0.571

High

1024279

PIPNA
Phosphatidylinositol transfer protein alpha isoform

2

1

High-throughput

0.558

High

1187380

RTN4
Reticulon-4

2

10

High-throughput

0.558

High

635322

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

1

High-throughput

0.549

High

835281

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

4

High-throughput

0.549

High

209024

CYB5B
Cytochrome b5 type B

1

4

High-throughput

0.536

High

220501

RNF13
E3 ubiquitin-protein ligase RNF13

1

9

High-throughput

0.536

High

244470

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

1

High-throughput

0.536

High

349427

TSN15
Tetraspanin-15

1

5

High-throughput

0.536

High

477423

CD63
CD63 antigen

1

5

High-throughput

0.536

High

1187382

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.536

High

1187379

SAYS1
SAYSvFN domain-containing protein 1

1

0

High-throughput

0.513

High

66439

ASB14
Ankyrin repeat and SOCS box protein 14

1

1

High-throughput

0.489

High

376610

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

2

High-throughput

0.489

High

618386

TSN8
Tetraspanin-8

1

5

High-throughput

0.489

High

877436

PIPNB
Phosphatidylinositol transfer protein beta isoform

1

1

High-throughput

0.489

High

999360

HBB
Hemoglobin subunit beta

1

2

High-throughput

0.489

High

1159065

C3AR
C3a anaphylatoxin chemotactic receptor

1

5

High-throughput

0.489

High

1187360

5HT3D
5-hydroxytryptamine receptor 3D

1

5

High-throughput

0.489

High

1187364

RN149
E3 ubiquitin-protein ligase RNF149

1

10

High-throughput

0.489

High

1187369

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

2

High-throughput

0.489

High

1187370

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.489

High

1187378

LPAR2
Lysophosphatidic acid receptor 2

1

9

High-throughput

0.489

High

275029

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

412030

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

535135

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

1162348

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

High-throughput

0.479

High

1187367

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1187368

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1187371

CI072
Guanine nucleotide exchange factor C9orf72

1

3

High-throughput

0.479

High

1187383

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

1187386

MTCH1
Mitochondrial carrier homolog 1

1

4

High-throughput

0.479

High

529907

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

106040

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

768334

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

904795

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.437

High

1004643

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.437

High

1099966

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

1178163

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1187359

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

1187375

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1187362

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.426

High

256042

S19A2
Thiamine transporter 1

1

1

High-throughput

0.407

High

260872

RAMP3
Receptor activity-modifying protein 3

1

2

High-throughput

0.407

High

466903

ACM4
Muscarinic acetylcholine receptor M4

1

4

High-throughput

0.407

High

607932

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

3

High-throughput

0.407

High

754030

CD80
T-lymphocyte activation antigen CD80

1

5

High-throughput

0.407

High

896392

ERF
ETS domain-containing transcription factor ERF

1

2

High-throughput

0.407

High

1187357

ARMC6
Armadillo repeat-containing protein 6

1

2

High-throughput

0.407

High

1187366

LPAR1
Lysophosphatidic acid receptor 1

1

7

High-throughput

0.407

High

639380

5NTD
5'-nucleotidase

3

0

High-throughput

0.347

High

1187354

T4S20
Transmembrane 4 L6 family member 20

3

0

High-throughput

0.347

High

1187376

TNR27
Tumor necrosis factor receptor superfamily member 27

3

0

High-throughput

0.347

High

1187355

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

0

High-throughput

0.313

High

167158

T4S5
Transmembrane 4 L6 family member 5

1

0

High-throughput

0.279

Low

190371

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

230965

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.279

Low

649183

GALA
Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide

1

0

High-throughput

0.279

Low

870044

KCNJ6
G protein-activated inward rectifier potassium channel 2

1

0

High-throughput

0.279

Low

1092373

TSN31
Tetraspanin-31

1

0

High-throughput

0.279

Low

1187356

STUM
Protein stum homolog

1

0

High-throughput

0.279

Low

1187361

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.279

Low

1187373

MDFI
MyoD family inhibitor

1

0

High-throughput

0.279

Low

1187381

PICK1
PRKCA-binding protein

1

0

High-throughput

0.279

Low

1187387

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1187363

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

1

0

High-throughput

0.249

Low

1187377

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

379521

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low

1130285

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025