Protein: TMC4
Voltage-gated chloride channel TMC4 (Transmembrane channel-like protein 4)

Gene: TMC4
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q7Z404

Gene Ontology (top 5):
GO:0005247 - voltage-gated chloride channel activity
GO:0005886 - plasma membrane
GO:0008381 - mechanosensitive monoatomic ion channel activity
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1205517

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.580

High

349464

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

1195352

ANO6
Anoctamin-6

1

1

High-throughput

0.536

High

1260349

ANO5
Anoctamin-5

1

1

High-throughput

0.536

High

1277747

S12A6
Solute carrier family 12 member 6

1

2

High-throughput

0.536

High

1277749

S12A4
Solute carrier family 12 member 4

1

2

High-throughput

0.536

High

1277750

S12A7
Solute carrier family 12 member 7

1

2

High-throughput

0.536

High

332662

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.513

High

354131

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.513

High

420009

B3A2
Anion exchange protein 2

1

0

High-throughput

0.513

High

1110798

PKD2
Polycystin-2

1

0

High-throughput

0.513

High

1125855

FZD2
Frizzled-2

1

0

High-throughput

0.513

High

1277737

T179B
Transmembrane protein 179B

1

0

High-throughput

0.513

High

1277739

ABCA7
Phospholipid-transporting ATPase ABCA7

1

0

High-throughput

0.513

High

1277740

AT11C
Phospholipid-transporting ATPase IG

1

0

High-throughput

0.513

High

1277746

NDRG3
Protein NDRG3

1

0

High-throughput

0.513

High

1277738

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.481

High

63671

A5PKU2
TUSC5 protein

1

1

High-throughput

0.470

High

610015

VGFR1
Vascular endothelial growth factor receptor 1

1

0

Small-scale

0.426

High

246296

MARH6
E3 ubiquitin-protein ligase MARCHF6

1

0

High-throughput

0.279

Low

975552

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.279

Low

1213629

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1218808

FOCAD
Focadhesin

1

0

High-throughput

0.279

Low

1277741

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.279

Low

1277742

TBC15
TBC1 domain family member 15

1

0

High-throughput

0.279

Low

1277743

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

1277744

RMXL1
RNA binding motif protein, X-linked-like-1

1

0

High-throughput

0.279

Low

1277745

CCD97
Coiled-coil domain-containing protein 97

1

0

High-throughput

0.279

Low

1277748

TPC1
Two pore channel protein 1

1

0

High-throughput

0.279

Low

1277751

S23IP
SEC23-interacting protein

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025