Protein: ERC6L
DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) (PLK1-interacting checkpoint helicase) (Tumor antigen BJ-HCC-15)

Gene: ERC6L, ERCC6L
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q2NKX8

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0003677 - DNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

861775

PLK1
Serine/threonine-protein kinase PLK1

9

4

Small-scale

0.755

High

1102052

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.665

High

885534

MLF1
Myeloid leukemia factor 1

3

0

High-throughput

0.638

High

1102041

TFDP3
Transcription factor Dp family member 3

3

0

High-throughput

0.638

High

791607

HD
Huntingtin

2

2

High-throughput

0.637

High

1074449

SIX1
Homeobox protein SIX1

2

11

High-throughput

0.628

High

1102040

MIDN
Midnolin

2

1

High-throughput

0.628

High

1102061

AASD1
Alanyl-tRNA editing protein Aarsd1

2

2

High-throughput

0.628

High

1102069

SIX2
Homeobox protein SIX2

2

14

High-throughput

0.628

High

1102055

WDFY2
WD repeat and FYVE domain-containing protein 2

3

11

High-throughput

0.609

High

154194

CHK1
Serine/threonine-protein kinase Chk1

2

0

High-throughput

0.602

High

456330

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

0

High-throughput

0.602

High

867600

BLM
RecQ-like DNA helicase BLM

1

20

High-throughput

0.575

High

982065

1433F
14-3-3 protein eta

1

3

High-throughput

0.554

High

1102044

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

720598

RFA3
Replication protein A 14 kDa subunit

2

7

High-throughput

0.549

High

71139

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

13

High-throughput

0.536

High

147163

FCHO1
F-BAR domain only protein 1

1

1

High-throughput

0.536

High

334207

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.536

High

618634

IF4B
Eukaryotic translation initiation factor 4B

1

7

High-throughput

0.536

High

631448

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.536

High

871587

HSP72
Heat shock-related 70 kDa protein 2

1

12

High-throughput

0.536

High

904630

1433G
14-3-3 protein gamma

1

3

High-throughput

0.536

High

1102049

MINK1
Misshapen-like kinase 1

1

4

High-throughput

0.536

High

1102053

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

1102056

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.536

High

1102057

TCPQM
T-complex protein 1 subunit theta-like 2

1

3

High-throughput

0.536

High

1102058

CDC5L
Cell division cycle 5-like protein

1

17

High-throughput

0.536

High

1102060

FEM1A
Protein fem-1 homolog A

1

5

High-throughput

0.536

High

1102062

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

1102063

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

903727

LMO4
LIM domain transcription factor LMO4

1

13

High-throughput

0.523

High

1102050

RBCC1
RB1-inducible coiled-coil protein 1

1

15

High-throughput

0.515

High

568983

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

1102048

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1102070

CN119
Uncharacterized protein C14orf119

1

0

High-throughput

0.513

High

1102072

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.513

High

414941

CDK1
Cyclin-dependent kinase 1

1

2

Small-scale

0.501

High

1102047

ZDH17
Palmitoyltransferase ZDHHC17

1

8

High-throughput

0.494

High

224621

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

1

High-throughput

0.489

High

719725

RADI
Radixin

1

2

High-throughput

0.489

High

529195

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.481

High

162802

XPO1
Exportin-1

1

2

High-throughput

0.479

High

227612

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

348694

RASN
GTPase NRas

1

3

High-throughput

0.479

High

377365

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

384933

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.479

High

552857

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

632290

TNR6
Tumor necrosis factor receptor superfamily member 6

1

3

High-throughput

0.479

High

651346

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

14

High-throughput

0.479

High

668729

PML
Protein PML

1

16

High-throughput

0.479

High

684070

1433S
14-3-3 protein sigma

1

3

High-throughput

0.479

High

684772

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.479

High

779513

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

1026432

RFA4
Replication protein A 30 kDa subunit

1

10

High-throughput

0.479

High

1035455

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.479

High

1102039

AMOT
Angiomotin

1

20

High-throughput

0.479

High

1102042

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.479

High

1102045

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

15

High-throughput

0.479

High

1102046

NAA40
N-alpha-acetyltransferase 40

1

7

High-throughput

0.479

High

1102051

GOGA1
Golgin subfamily A member 1

1

4

High-throughput

0.479

High

1102054

SNX27
Sorting nexin-27

1

1

High-throughput

0.479

High

1102059

BARD1
BRCA1-associated RING domain protein 1

1

9

High-throughput

0.479

High

1102064

WWTR1
WW domain-containing transcription regulator protein 1

1

13

High-throughput

0.479

High

1102065

CLPB
Mitochondrial disaggregase

1

9

High-throughput

0.479

High

1102067

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

1102071

BCLF1
Bcl-2-associated transcription factor 1

1

11

High-throughput

0.479

High

1102073

FBW1B
F-box/WD repeat-containing protein 11

1

19

High-throughput

0.479

High

281648

WFS1
Wolframin

1

1

High-throughput

0.470

High

217893

PRKY
Putative serine/threonine-protein kinase PRKY

1

3

High-throughput

0.445

High

1035322

TOP3A
DNA topoisomerase 3-alpha

1

1

High-throughput

0.445

High

1102043

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1102066

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.437

High

1102068

RMI1
RecQ-mediated genome instability protein 1

1

0

High-throughput

0.426

High

64014

SPDE4
Speedy protein E4

1

0

High-throughput

0.279

Low

1101703

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

100815

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024