Protein: SIRPD
Signal-regulatory protein delta (SIRP-delta) (Protein tyrosine phosphatase non-receptor type substrate 1-like 2)

Gene: SIRPD
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9H106

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1393560

DIRA2
GTP-binding protein Di-Ras2

2

0

High-throughput

0.770

High

161083

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

4

High-throughput

0.691

High

274915

LRP5
Low-density lipoprotein receptor-related protein 5

1

2

High-throughput

0.691

High

287606

LRP6
Low-density lipoprotein receptor-related protein 6

1

2

High-throughput

0.691

High

380656

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

1

High-throughput

0.691

High

452114

PROS
Vitamin K-dependent protein S

1

5

High-throughput

0.691

High

464470

TSP1
Thrombospondin-1

1

5

High-throughput

0.691

High

472206

TRFM
Melanotransferrin

1

1

High-throughput

0.691

High

551893

CO6A2

1

1

High-throughput

0.691

High

648661

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.691

High

650404

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.691

High

709078

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

2

High-throughput

0.691

High

857555

NOTC1
Neurogenic locus notch homolog protein 1

1

2

High-throughput

0.691

High

873791

CD151
CD151 antigen

1

1

High-throughput

0.691

High

907936

PLXA3
Plexin-A3

1

2

High-throughput

0.691

High

1022565

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

1

High-throughput

0.691

High

1037040

DSC2
Desmocollin-2

1

2

High-throughput

0.691

High

1098331

SEM3B
Semaphorin-3B

1

1

High-throughput

0.691

High

1105777

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

4

High-throughput

0.691

High

1294376

FRAS1
Extracellular matrix organizing protein FRAS1

1

8

High-throughput

0.691

High

1366667

SORL
Sortilin-related receptor

1

3

High-throughput

0.691

High

1366834

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

1

High-throughput

0.691

High

1408458

SEM3C
Semaphorin-3C

1

1

High-throughput

0.691

High

1430737

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

3

High-throughput

0.691

High

1430739

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

4

High-throughput

0.691

High

1430742

PLXA1
Plexin-A1

1

3

High-throughput

0.691

High

1430744

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

4

High-throughput

0.691

High

1430745

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

2

High-throughput

0.691

High

1430747

JAG2
Protein jagged-2

1

1

High-throughput

0.691

High

247535

FZD6
Frizzled-6

1

0

High-throughput

0.656

High

467850

BGLR
Beta-glucuronidase

1

0

High-throughput

0.656

High

571249

PERF
Perforin-1

1

0

High-throughput

0.656

High

592698

ITB4
Integrin beta-4

1

0

High-throughput

0.656

High

719739

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

0

High-throughput

0.656

High

720432

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

0

High-throughput

0.656

High

903003

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.656

High

1055357

APLP2
Amyloid beta precursor like protein 2

1

0

High-throughput

0.656

High

1249739

SE6L2
Seizure 6-like protein 2

1

0

High-throughput

0.656

High

1390350

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.656

High

1430738

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

0

High-throughput

0.656

High

1022468

IDD
Integral membrane protein DGCR2/IDD

1

4

High-throughput

0.618

High

1243284

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

1

High-throughput

0.618

High

1281699

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

4

High-throughput

0.618

High

1292139

ANR46
Ankyrin repeat domain-containing protein 46

1

2

High-throughput

0.618

High

1307718

CILP2
Cartilage intermediate layer protein 2

1

1

High-throughput

0.618

High

1312535

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

1

High-throughput

0.618

High

1430746

EPDR1
Mammalian ependymin-related protein 1

2

0

High-throughput

0.602

High

760803

BMP8B
Bone morphogenetic protein 8B

1

0

High-throughput

0.578

High

380586

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

1

High-throughput

0.575

High

1127599

FAT1
Protocadherin Fat 1

1

3

High-throughput

0.575

High

1250384

PCD23
Protocadherin-23

1

3

High-throughput

0.575

High

1430750

PCDBB
Protocadherin beta-11

1

0

High-throughput

0.546

High

183298

LAMA5
Laminin subunit alpha-5

1

3

High-throughput

0.536

High

937436

LAMB2
Laminin subunit beta-2

1

2

High-throughput

0.536

High

1126047

GAS6
Growth arrest-specific protein 6

1

5

High-throughput

0.536

High

1248236

CSPG4
Chondroitin sulfate proteoglycan 4

1

5

High-throughput

0.536

High

1324222

VWDE
von Willebrand factor D and EGF domain-containing protein

1

3

High-throughput

0.536

High

1405046

SORT
Sortilin

1

1

High-throughput

0.536

High

244495

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

0

High-throughput

0.513

High

354174

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.513

High

1175839

T132A
Transmembrane protein 132A

1

0

High-throughput

0.513

High

1212693

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.513

High

1382882

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.513

High

1206141

TGO1
Transport and Golgi organization protein 1 homolog

1

1

High-throughput

0.489

High

1225411

METRL
Meteorin-like protein

1

1

High-throughput

0.489

High

1249906

CREL2
Protein disulfide isomerase CRELD2

1

4

High-throughput

0.489

High

1308852

P3H3
Prolyl 3-hydroxylase 3

1

1

High-throughput

0.489

High

1368431

SC65
Endoplasmic reticulum protein SC65

1

1

High-throughput

0.489

High

1430736

CHRD
Chordin

1

4

High-throughput

0.489

High

1430743

METRN
Meteorin

1

1

High-throughput

0.489

High

1399545

MIA2
Melanoma inhibitory activity protein 2

1

2

High-throughput

0.407

High

1198920

HIKES
Protein Hikeshi

2

0

High-throughput

0.328

High

1349612

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

2

0

High-throughput

0.328

High

928547

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.288

High

600629

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.279

Low

771677

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.279

Low

932388

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.279

Low

1193211

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

0

High-throughput

0.279

Low

1288102

OAF
Out at first protein homolog

1

0

High-throughput

0.279

Low

1333841

TTC13
Tetratricopeptide repeat protein 13

1

0

High-throughput

0.279

Low

1364146

TM131
Transmembrane protein 131

1

0

High-throughput

0.279

Low

1372144

EXT2
Exostosin-2

1

0

High-throughput

0.279

Low

1411840

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

1430735

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.279

Low

1430740

SELN
Selenoprotein N

1

0

High-throughput

0.279

Low

1430741

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

1430748

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.279

Low

1430749

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025