Protein: COPRS
Coordinator of PRMT5 and differentiation stimulator (Cooperator of PRMT5) (Protein TTP1)

Gene: COPRS
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9NQ92

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

162707

ANM5
Protein arginine N-methyltransferase 5

5

1

Small-scale

0.721

High

211428

RFOX2
RNA binding protein fox-1 homolog 2

3

2

High-throughput

0.667

High

574483

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

1

High-throughput

0.662

High

729468

HNRH1
Heterogeneous nuclear ribonucleoprotein H

3

1

High-throughput

0.662

High

974342

LSM6
U6 snRNA-associated Sm-like protein LSm6

3

2

High-throughput

0.662

High

1446868

GAR1
H/ACA ribonucleoprotein complex subunit 1

4

0

High-throughput

0.661

High

586904

RS2
Small ribosomal subunit protein uS5

3

0

High-throughput

0.638

High

644080

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

0

High-throughput

0.638

High

1411720

RIOK1
Serine/threonine-protein kinase RIO1

3

0

High-throughput

0.634

High

991257

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

1

High-throughput

0.628

High

1446867

RFOX1
RNA binding protein fox-1 homolog 1

2

2

High-throughput

0.628

High

1410380

MEP50
Methylosome protein WDR77

3

0

High-throughput

0.622

High

345009

WIZ
Protein Wiz

3

0

High-throughput

0.616

High

477112

IL6RA
Interleukin-6 receptor subunit alpha

2

0

High-throughput

0.602

High

926231

ICLN
Methylosome subunit pICln

2

0

High-throughput

0.602

High

960903

RL15
Large ribosomal subunit protein eL15

2

0

High-throughput

0.602

High

963375

PFD3
Prefoldin subunit 3

2

0

High-throughput

0.602

High

1013461

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

2

0

High-throughput

0.602

High

1120001

CIRBP
Cold-inducible RNA-binding protein

2

0

High-throughput

0.602

High

938814

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

2

1

High-throughput

0.601

High

998839

H31
Histone H3.1

2

1

Small-scale

0.601

High

1446875

LSM4
U6 snRNA-associated Sm-like protein LSm4

2

1

High-throughput

0.601

High

332341

ATE1
Arginyl-tRNA--protein transferase 1

2

0

High-throughput

0.576

High

1257826

ACD11
Acyl-CoA dehydrogenase family member 11

2

0

High-throughput

0.576

High

1446873

MEMO1
Protein MEMO1

2

0

High-throughput

0.576

High

249784

DOK2
Docking protein 2

2

0

High-throughput

0.547

High

631495

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

320593

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

1

High-throughput

0.536

High

974284

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

2

High-throughput

0.536

High

974851

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

High-throughput

0.536

High

1199466

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

1

High-throughput

0.536

High

1396308

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

High-throughput

0.536

High

1436916

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

High-throughput

0.536

High

1446872

E41L3
Band 4.1-like protein 3

1

1

High-throughput

0.536

High

980383

H4
Histone H4

1

0

Small-scale

0.527

High

170366

AURKA
Aurora kinase A

1

0

High-throughput

0.513

High

335510

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.513

High

732717

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

909193

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.513

High

944859

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.513

High

1231223

KDM4D
Lysine-specific demethylase 4D

1

0

High-throughput

0.513

High

1434891

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.513

High

1446874

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.513

High

1162055

H31T
Histone H3.1t

1

1

Small-scale

0.501

High

1029948

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.480

High

1119530

PEBB
Core-binding factor subunit beta

1

0

Small-scale

0.480

High

1407894

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

316044

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

350145

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

428236

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.458

High

766225

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

971135

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

972031

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.458

High

1033248

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1229698

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1358111

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

1435331

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1438979

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.458

High

1446869

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1446870

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

1446871

XPO7
Exportin-7

1

0

High-throughput

0.458

High

530417

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

907591

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.426

High

1103398

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

1235683

NIPBL
Nipped-B-like protein

1

0

High-throughput

0.426

High

1419917

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

1386515

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

2

0

High-throughput

0.328

High

615200

PACA
Pituitary adenylate cyclase-activating polypeptide

2

0

High-throughput

0.318

High

1312848

CI040
Uncharacterized protein C9orf40

1

0

High-throughput

0.279

Low

1328408

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.279

Low

1435925

RDD1
Required for drug-induced death protein 1

1

0

High-throughput

0.279

Low

294375

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1249636

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.232

Low

1386836

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025