HitPredict - High confidence protein-protein interactions

Protein: C1TC
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]

Gene: C1TC, Mthfd1
Organism: Mus musculus
Interactions: 11
UniProt ID: Q922D8

Gene Ontology (top 5):
GO:0000105 - L-histidine biosynthetic process
GO:0001780 - neutrophil homeostasis
GO:0001843 - neural tube closure
GO:0004329 - formate-tetrahydrofolate ligase activity
GO:0004477 - methenyltetrahydrofolate cyclohydrolase activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1193929	FACD2 Fanconi anemia group D2 protein homolog	1	1	High-throughput	0.479	High
956263	NXN Nucleoredoxin	1	0	Small-scale	0.458	High
1207327	GEPH Gephyrin [Includes: Molybdopterin adenylyltransferase	1	0	High-throughput	0.458	High
222574	ITB3 Integrin beta-3	1	1	High-throughput	0.457	High
1206667	ANS1B Ankyrin repeat and sterile alpha motif domain-containing protein 1B	1	6	High-throughput	0.445	High
681269	SC6A1 Sodium- and chloride-dependent GABA transporter 1	1	2	High-throughput	0.437	High
1141695	SC6A4 Sodium-dependent serotonin transporter	1	2	High-throughput	0.437	High
1265385	EED Polycomb protein EED	1	3	High-throughput	0.437	High
906342	PP1A Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	1	0	High-throughput	0.426	High
103165	G3X9H5 Huntingtin	1	0	High-throughput	0.249	Low
857773	HMGA2 High mobility group protein HMGI-C	1	0	High-throughput	0.232	Low

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024