Protein: K2C80
Keratin, type II cytoskeletal 80 (Cytokeratin-80) (CK-80) (Keratin-80) (K80) (Type-II keratin Kb20)

Gene: K2C80, KRT80
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q6KB66

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0030280 - structural constituent of skin epidermis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580041

K1C15
Keratin, type I cytoskeletal 15

3

20

High-throughput

0.871

High

729030

K1C20
Keratin, type I cytoskeletal 20

3

20

High-throughput

0.871

High

444395

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.794

High

1055188

K1H2
Keratin, type I cuticular Ha2

2

20

High-throughput

0.794

High

280611

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.783

High

280806

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

280999

KRT38
Keratin, type I cuticular Ha8

2

20

High-throughput

0.783

High

359370

K1C14
Keratin, type I cytoskeletal 14

2

20

High-throughput

0.783

High

445070

K1C16
Keratin, type I cytoskeletal 16

2

20

High-throughput

0.783

High

1055055

KT33B
Keratin, type I cuticular Ha3-II

2

20

High-throughput

0.783

High

1071219

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.783

High

1101627

K1C24
Keratin, type I cytoskeletal 24

2

20

High-throughput

0.783

High

1154013

K1C28
Keratin, type I cytoskeletal 28

2

20

High-throughput

0.783

High

1154017

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

1154014

K1C25
Keratin, type I cytoskeletal 25

1

20

High-throughput

0.621

High

529268

CFTR
Cystic fibrosis transmembrane conductance regulator

2

15

High-throughput

0.611

High

1154033

AIRIM
AFG2-interacting ribosome maturation factor

2

2

High-throughput

0.606

High

1154036

CSN3
COP9 signalosome complex subunit 3

2

0

High-throughput

0.580

High

838049

MEOX2
Homeobox protein MOX-2

1

5

High-throughput

0.573

High

314517

LCA5L
Lebercilin-like protein

2

5

High-throughput

0.553

High

638314

RBTN2
Rhombotin-2

2

7

High-throughput

0.553

High

1020735

TRAF2
TNF receptor-associated factor 2

1

13

High-throughput

0.536

High

1154019

TANK
TRAF family member-associated NF-kappa-B activator

1

1

High-throughput

0.536

High

1154020

CSN5
COP9 signalosome complex subunit 5

1

12

High-throughput

0.536

High

603062

OSBP1
Oxysterol-binding protein 1

1

0

High-throughput

0.513

High

1154016

STYX
Serine/threonine/tyrosine-interacting protein

1

0

Small-scale

0.513

High

1154037

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

7

Small-scale

0.501

High

1154027

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

10

High-throughput

0.489

High

1154030

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.489

High

1154032

IFT57
Intraflagellar transport protein 57 homolog

1

1

High-throughput

0.489

High

1154034

RRBP1
Ribosome-binding protein 1

1

5

High-throughput

0.489

High

134084

DDX3X
ATP-dependent RNA helicase DDX3X

1

3

Small-scale

0.479

High

214297

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

233506

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

278113

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.479

High

282678

RNF8
E3 ubiquitin-protein ligase RNF8

1

9

High-throughput

0.479

High

303300

HEXI1
Protein HEXIM1

1

17

High-throughput

0.479

High

319879

HERC2
E3 ubiquitin-protein ligase HERC2

1

3

High-throughput

0.479

High

386925

P53
Cellular tumor antigen p53

1

6

Small-scale

0.479

High

453424

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

6

High-throughput

0.479

High

504249

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

622485

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.479

High

1018534

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

17

High-throughput

0.479

High

1046074

DX39B
Spliceosome RNA helicase DDX39B

1

15

High-throughput

0.479

High

1059676

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

17

High-throughput

0.479

High

1154011

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

1154015

ARMC8
Armadillo repeat-containing protein 8

1

2

High-throughput

0.479

High

1154018

HDAC2
Histone deacetylase 2

1

8

High-throughput

0.479

High

1154021

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

5

Small-scale

0.479

High

1154024

ACE2
Angiotensin-converting enzyme 2

1

5

High-throughput

0.479

High

1154026

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.479

High

1154028

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

8

High-throughput

0.479

High

1154029

ANLN
Anillin

1

9

High-throughput

0.479

High

1154035

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

455558

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

267416

ECI2
Enoyl-CoA delta isomerase 2

1

3

High-throughput

0.445

High

717934

BMI1
Polycomb complex protein BMI-1

1

10

High-throughput

0.445

High

891186

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

1130203

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

6

High-throughput

0.445

High

1154012

MEPCE
7SK snRNA methylphosphate capping enzyme

1

8

High-throughput

0.437

High

1154022

CIC
Protein capicua homolog

1

4

High-throughput

0.437

High

1154025

DDX24
ATP-dependent RNA helicase DDX24

1

15

High-throughput

0.437

High

1139568

RNLS
Renalase

1

0

Small-scale

0.426

High

1154023

PSF3
DNA replication complex GINS protein PSF3

2

0

High-throughput

0.316

High

396525

CP17A
Steroid 17-alpha-hydroxylase/17,20 lyase

1

0

High-throughput

0.279

Low

1154031

FBX28
F-box only protein 28

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024