Protein: LCA5
Lebercilin (Leber congenital amaurosis 5 protein)

Gene: LCA5
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q86VQ0

Gene Ontology (top 5):
GO:0005813 - centrosome
GO:0005929 - cilium
GO:0005930 - axoneme
GO:0015031 - protein transport
GO:0032391 - photoreceptor connecting cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1068780

PCM1
Pericentriolar material 1 protein

3

3

High-throughput

0.657

High

1202246

DYL2
Dynein light chain 2, cytoplasmic

3

7

High-throughput

0.656

High

928368

DYL1
Dynein light chain 1, cytoplasmic

3

7

High-throughput

0.650

High

1202258

IFT27
Intraflagellar transport protein 27 homolog

3

15

High-throughput

0.650

High

904802

1433G
14-3-3 protein gamma

4

20

High-throughput

0.619

High

1202275

RCOR3
REST corepressor 3

3

5

High-throughput

0.616

High

214723

SSNA1
Microtubule nucleation factor SSNA1

2

0

High-throughput

0.602

High

1202277

TFP11
Tuftelin-interacting protein 11

3

3

High-throughput

0.596

High

1202227

ARMC8
Armadillo repeat-containing protein 8

2

2

High-throughput

0.574

High

1202262

TSYL1
Testis-specific Y-encoded-like protein 1

2

5

High-throughput

0.574

High

1024253

IFT88
Intraflagellar transport protein 88 homolog

2

5

High-throughput

0.571

High

1077010

MARE1
Microtubule-associated protein RP/EB family member 1

2

1

High-throughput

0.571

High

1202233

MIPT3
TRAF3-interacting protein 1

2

8

High-throughput

0.571

High

1202237

IFT81
Intraflagellar transport protein 81 homolog

2

17

High-throughput

0.571

High

1202247

IFT74
Intraflagellar transport protein 74 homolog

2

20

High-throughput

0.571

High

1202264

IFT22
Intraflagellar transport protein 22 homolog

2

9

High-throughput

0.571

High

1202274

IFT80
Intraflagellar transport protein 80 homolog

2

18

High-throughput

0.571

High

1202279

IF172
Intraflagellar transport protein 172 homolog

2

15

High-throughput

0.571

High

272625

OFD1
Centriole and centriolar satellite protein OFD1

1

18

High-throughput

0.554

High

1131754

CE170
Centrosomal protein of 170 kDa

1

15

High-throughput

0.554

High

1202242

GCC1
GRIP and coiled-coil domain-containing protein 1

2

17

High-throughput

0.553

High

47939

IFT56
Intraflagellar transport protein 56

2

0

High-throughput

0.547

High

1202226

IT70A
Intraflagellar transport protein 70A

2

0

High-throughput

0.547

High

1202229

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.547

High

1202240

CLUA1
Clusterin-associated protein 1

2

0

High-throughput

0.547

High

1202269

IFT46
Intraflagellar transport protein 46 homolog

2

0

High-throughput

0.547

High

1202270

IFT57
Intraflagellar transport protein 57 homolog

2

0

High-throughput

0.547

High

312316

IPO7
Importin-7

2

8

High-throughput

0.537

High

982225

1433F
14-3-3 protein eta

2

20

High-throughput

0.537

High

1202251

NP1L4
Nucleosome assembly protein 1-like 4

2

7

High-throughput

0.537

High

1202260

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

5

High-throughput

0.537

High

1100877

MOONR
Protein moonraker

1

0

High-throughput

0.530

High

1202284

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.530

High

770625

TXLNA
Alpha-taxilin

1

18

High-throughput

0.523

High

59221

VWA8
von Willebrand factor A domain-containing protein 8

2

8

High-throughput

0.521

High

123999

SPT5H
Transcription elongation factor SPT5

2

7

High-throughput

0.521

High

127313

IPO5
Importin-5

2

4

High-throughput

0.521

High

273874

NU155
Nuclear pore complex protein Nup155

2

3

High-throughput

0.521

High

340486

PGK1
Phosphoglycerate kinase 1

2

1

High-throughput

0.521

High

536903

TRI27
Zinc finger protein RFP

2

13

High-throughput

0.521

High

571027

PYRG1
CTP synthase 1

2

1

High-throughput

0.521

High

647067

1433T
14-3-3 protein theta

2

20

High-throughput

0.521

High

683509

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.521

High

687241

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

2

1

High-throughput

0.521

High

898956

PSME3
Proteasome activator complex subunit 3

2

1

High-throughput

0.521

High

909762

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.521

High

927250

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.521

High

972542

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

2

7

High-throughput

0.521

High

981319

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

4

High-throughput

0.521

High

997576

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

2

2

High-throughput

0.521

High

1060812

IMB1
Importin subunit beta-1

2

7

High-throughput

0.521

High

1069314

IPYR
Inorganic pyrophosphatase

2

1

High-throughput

0.521

High

1070853

RCN1
Reticulocalbin-1

2

4

High-throughput

0.521

High

1163008

TRAF7
E3 ubiquitin-protein ligase TRAF7

2

15

High-throughput

0.521

High

1202243

KCD12
BTB/POZ domain-containing protein KCTD12

2

6

High-throughput

0.521

High

1202249

VPS35
Vacuolar protein sorting-associated protein 35

2

1

High-throughput

0.521

High

1202257

NOC4L
Nucleolar complex protein 4 homolog

2

3

High-throughput

0.521

High

1202265

XPO5
Exportin-5

2

6

High-throughput

0.521

High

1202266

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

2

2

High-throughput

0.521

High

1202278

SAE2
SUMO-activating enzyme subunit 2

2

1

High-throughput

0.521

High

1202282

CSN3
COP9 signalosome complex subunit 3

2

1

High-throughput

0.521

High

942770

SRPK2
SRSF protein kinase 2

1

16

High-throughput

0.520

High

1202287

IFT25
Intraflagellar transport protein 25 homolog

1

0

High-throughput

0.513

High

1185112

MAEA
E3 ubiquitin-protein transferase MAEA

1

1

High-throughput

0.489

High

201955

WDR62
WD repeat-containing protein 62

1

11

High-throughput

0.479

High

861823

PLK1
Serine/threonine-protein kinase PLK1

1

5

High-throughput

0.479

High

1093017

CSPP1
Centrosome and spindle pole-associated protein 1

1

1

High-throughput

0.479

High

1135936

CE162
Centrosomal protein of 162 kDa

1

18

High-throughput

0.479

High

1147614

FTM
Protein fantom

1

19

High-throughput

0.479

High

1190364

HAUS6
HAUS augmin-like complex subunit 6

1

1

High-throughput

0.479

High

1200967

LUZP1
Leucine zipper protein 1

1

18

High-throughput

0.479

High

1202230

NIN
Ninein

1

18

High-throughput

0.479

High

1202231

CE120
Centrosomal protein of 120 kDa

1

18

High-throughput

0.479

High

1202232

NEDD1
Protein NEDD1

1

15

High-throughput

0.479

High

1202235

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.479

High

1202241

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.479

High

1202244

TBC31
TBC1 domain family member 31

1

16

High-throughput

0.479

High

1202256

TCHP
Trichoplein keratin filament-binding protein

1

18

High-throughput

0.479

High

1202272

CEP72
Centrosomal protein of 72 kDa

1

3

High-throughput

0.479

High

1202276

WRP73
WD repeat-containing protein WRAP73

1

20

High-throughput

0.479

High

1202280

MTUS1
Microtubule-associated tumor suppressor 1

1

18

High-throughput

0.479

High

1202283

CP131
Centrosomal protein of 131 kDa

1

17

High-throughput

0.479

High

1202285

NINL
Ninein-like protein

1

18

High-throughput

0.479

High

58507

CCD66
Coiled-coil domain-containing protein 66

1

0

High-throughput

0.458

High

1107886

F161A
Protein FAM161A

1

0

Small-scale

0.458

High

1147719

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1202234

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.458

High

1202252

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

1202255

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

1202261

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

151069

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

14

High-throughput

0.437

High

166582

DCLK1
Serine/threonine-protein kinase DCLK1

1

4

High-throughput

0.437

High

166959

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

7

High-throughput

0.437

High

178207

IPO8
Importin-8

1

6

High-throughput

0.437

High

718970

PHB1
Prohibitin 1

1

7

High-throughput

0.437

High

876837

NP1L1
Nucleosome assembly protein 1-like 1

1

7

High-throughput

0.437

High

1019329

TRI26
Tripartite motif-containing protein 26

1

15

High-throughput

0.437

High

1052091

MAP7
Ensconsin

1

20

High-throughput

0.437

High

1066341

KIF14
Kinesin-like protein KIF14

1

14

High-throughput

0.437

High

1108850

MA7D1
MAP7 domain-containing protein 1

1

16

High-throughput

0.437

High

1202228

MA7D3
MAP7 domain-containing protein 3

1

11

High-throughput

0.437

High

1202239

MRTFA
Myocardin-related transcription factor A

1

12

High-throughput

0.437

High

1202248

CC138
Coiled-coil domain-containing protein 138

1

1

High-throughput

0.437

High

1202250

MA7D2
MAP7 domain-containing protein 2

1

20

High-throughput

0.437

High

1202253

GPTC1
G patch domain-containing protein 1

1

3

High-throughput

0.437

High

1202254

WDR83
WD repeat domain-containing protein 83

1

19

High-throughput

0.437

High

1202259

TRIM2
Tripartite motif-containing protein 2

1

17

High-throughput

0.437

High

1202267

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

High-throughput

0.437

High

1202268

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.437

High

1202271

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.437

High

1202286

C170B
Centrosomal protein of 170 kDa protein B

1

13

High-throughput

0.437

High

1202281

SUFU
Suppressor of fused homolog

2

0

High-throughput

0.316

High

199200

ZNHI1
Zinc finger HIT domain-containing protein 1

2

0

High-throughput

0.298

High

1092580

KNOP1
Lysine-rich nucleolar protein 1

2

0

High-throughput

0.298

High

1202236

BRI3B
BRI3-binding protein

2

0

High-throughput

0.298

High

1202245

PTCD3
Small ribosomal subunit protein mS39

2

0

High-throughput

0.298

High

1202288

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

2

0

High-throughput

0.298

High

1115838

MAP9
Microtubule-associated protein 9

1

0

High-throughput

0.249

Low

1133789

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

0

High-throughput

0.249

Low

1202225

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.249

Low

1202238

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

0

High-throughput

0.249

Low

1202263

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.249

Low

1202273

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024