Protein: BPNT1
3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (3'-phosphoadenosine 5'-phosphate phosphatase) (PAP phosphatase) (Bisphosphate 3'-nucleotidase 1) (BPntase 1) (HsPIP) (Inositol-polyphosphate 1-phosphatase) (EC 3.1.3.57)

Gene: BPNT1
Organism: Homo sapiens
Interactions: 89
UniProt ID: O95861

Gene Ontology (top 5):
GO:0004441 - inositol-1,4-bisphosphate 1-phosphatase activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006139 - nucleobase-containing compound metabolic process
GO:0007399 - nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

61885

GTPBA
GTP-binding protein 10

2

2

High-throughput

0.628

High

73980

MYO9A
Unconventional myosin-IXa

2

1

High-throughput

0.628

High

349654

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

2

1

High-throughput

0.628

High

349673

SYLM
Leucine--tRNA ligase, mitochondrial

2

1

High-throughput

0.628

High

349678

SYVM
Valine--tRNA ligase, mitochondrial

2

1

High-throughput

0.628

High

349688

MICU2
Calcium uptake protein 2, mitochondrial

2

1

High-throughput

0.628

High

349706

MTG2
Mitochondrial ribosome-associated GTPase 2

2

2

High-throughput

0.628

High

349671

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

2

3

High-throughput

0.611

High

71685

NUD19
Acyl-coenzyme A diphosphatase NUDT19

2

0

High-throughput

0.602

High

177502

MRPP3
Mitochondrial ribonuclease P catalytic subunit

2

0

High-throughput

0.602

High

292889

RNH2A
Ribonuclease H2 subunit A

2

0

High-throughput

0.602

High

349650

PYC
Pyruvate carboxylase, mitochondrial

2

0

High-throughput

0.602

High

349653

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

2

0

High-throughput

0.602

High

349657

IF2M
Translation initiation factor IF-2, mitochondrial

2

0

High-throughput

0.602

High

349658

PPOX
Protoporphyrinogen oxidase

2

0

High-throughput

0.602

High

349660

DPOG1
DNA polymerase subunit gamma-1

2

0

High-throughput

0.602

High

349663

ABD18
Protein ABHD18

2

0

High-throughput

0.602

High

349667

TOP3A
DNA topoisomerase 3-alpha

2

0

High-throughput

0.602

High

349676

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

2

0

High-throughput

0.602

High

349682

ACD10
Acyl-CoA dehydrogenase family member 10

2

0

High-throughput

0.602

High

349689

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

2

0

High-throughput

0.602

High

349690

CHDH
Choline dehydrogenase, mitochondrial

2

0

High-throughput

0.602

High

349691

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

2

0

High-throughput

0.602

High

349693

DC2I1
Cytoplasmic dynein 2 intermediate chain 1

2

0

High-throughput

0.602

High

349696

RRF2M
Ribosome-releasing factor 2, mitochondrial

2

0

High-throughput

0.602

High

349697

NSUN4
5-cytosine rRNA methyltransferase NSUN4

2

0

High-throughput

0.602

High

349712

D39U1
Epimerase family protein SDR39U1

2

0

High-throughput

0.602

High

349713

MOCS1
Molybdenum cofactor biosynthesis protein 1

2

0

High-throughput

0.602

High

349716

FEM1B
Protein fem-1 homolog B

2

0

High-throughput

0.602

High

349717

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

2

0

High-throughput

0.602

High

349677

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.547

High

229113

GTPB6
Putative GTP-binding protein 6

1

2

High-throughput

0.536

High

349666

MYO9B
Unconventional myosin-IXb

1

1

High-throughput

0.536

High

349683

SYDM
Aspartate--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

349686

LARP4
La-related protein 4

1

1

High-throughput

0.536

High

349700

SYNM
Asparaginyl-tRNA synthetase

1

1

High-throughput

0.536

High

349709

TRXR2
Thioredoxin reductase 2, mitochondrial

1

2

High-throughput

0.536

High

349710

SYSM
Serine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

349720

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

1

High-throughput

0.536

High

166599

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.513

High

349647

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.513

High

349648

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

0

High-throughput

0.513

High

349649

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

349659

IDH3G
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

1

0

High-throughput

0.513

High

349661

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

349662

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

349668

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.513

High

349669

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

1

0

High-throughput

0.513

High

349674

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

349675

LRC41
Leucine-rich repeat-containing protein 41

1

0

High-throughput

0.513

High

349684

TRI65
E3 ubiquitin-protein ligase TRIM65

1

0

High-throughput

0.513

High

349687

NDUF7
Protein arginine methyltransferase NDUFAF7, mitochondrial

1

0

High-throughput

0.513

High

349698

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

0

High-throughput

0.513

High

349702

CDC6
Cell division control protein 6 homolog

1

0

High-throughput

0.513

High

349704

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.513

High

349705

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.513

High

349707

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

349708

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.513

High

349719

NFS1
Cysteine desulfurase

1

0

High-throughput

0.513

High

349652

CADH2
Cadherin-2

1

1

High-throughput

0.489

High

240406

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

349656

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

349672

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

349714

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

349718

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

349646

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

349664

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

349681

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.445

High

213027

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

Small-scale

0.438

High

349670

CUL4A
Cullin-4A

1

3

High-throughput

0.437

High

349685

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

142262

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.426

High

261033

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

349665

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.426

High

349699

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

76594

B4DYI6
cDNA FLJ60196, highly similar to Methylglutaconyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.407

High

349680

TBC9B
TBC1 domain family member 9B

2

0

High-throughput

0.328

High

349701

REXO5
RNA exonuclease 5

2

0

High-throughput

0.328

High

349703

APOL2
Apolipoprotein L2

2

0

High-throughput

0.328

High

62872

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.279

Low

349679

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

0

High-throughput

0.279

Low

349694

PCNP
PEST proteolytic signal-containing nuclear protein

1

0

High-throughput

0.279

Low

349715

MCM8
DNA helicase MCM8

1

0

High-throughput

0.279

Low

349645

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

349651

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

349655

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

349695

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.249

Low

349692

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.232

Low

349711

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025