Protein: GDN
Glia-derived nexin (GDN) (Peptidase inhibitor 7) (PI-7) (Protease nexin 1) (PN-1) (Protease nexin I) (Serpin E2)

Gene: GDN, SERPINE2
Organism: Homo sapiens
Interactions: 38
UniProt ID: P07093

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005102 - signaling receptor binding
GO:0005539 - glycosaminoglycan binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

366461

UROK
Urokinase-type plasminogen activator

4

20

Small-scale

0.899

High

450170

KLK2
Kallikrein-2

3

20

High-throughput

0.861

High

450191

KLK13
Kallikrein-13

3

20

High-throughput

0.855

High

450193

ST14
Suppressor of tumorigenicity 14 protein

1

20

High-throughput

0.691

High

366521

TPA
Tissue-type plasminogen activator

1

20

High-throughput

0.665

High

450174

SG2A2
Mammaglobin-A

2

0

High-throughput

0.602

High

424574

PAI1
Plasminogen activator inhibitor 1

1

11

High-throughput

0.575

High

450179

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.553

High

450166

ETS2
Protein C-ets-2

1

5

High-throughput

0.541

High

73760

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

4

High-throughput

0.536

High

380725

HBD
Hemoglobin subunit delta

1

2

High-throughput

0.536

High

450163

FURIN
Furin

1

4

High-throughput

0.536

High

450164

CCL3
C-C motif chemokine 3

1

1

High-throughput

0.536

High

450165

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

450169

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.536

High

450173

LCN6
Epididymal-specific lipocalin-6

1

3

High-throughput

0.536

High

450176

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.536

High

450182

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.536

High

450183

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

4

High-throughput

0.536

High

450190

FBX2
F-box only protein 2

1

6

High-throughput

0.536

High

423725

APOD
Apolipoprotein D

1

0

High-throughput

0.513

High

450167

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

0

High-throughput

0.513

High

450181

SVOPL
Putative transporter SVOPL

1

1

High-throughput

0.489

High

450184

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.489

High

450192

TSN16
Tetraspanin-16

1

4

High-throughput

0.489

High

450168

TIMP2
Metalloproteinase inhibitor 2

1

2

High-throughput

0.479

High

450175

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

450187

FBX6
F-box only protein 6

1

6

High-throughput

0.479

High

450171

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

3

High-throughput

0.445

High

217719

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

450188

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

450172

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.328

High

450177

RTN1
Reticulon-1

2

0

High-throughput

0.328

High

450180

FAM9B
Protein FAM9B

1

0

High-throughput

0.299

High

450185

CAD23
Cadherin-23

1

0

High-throughput

0.279

Low

450186

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.279

Low

450189

NAT8B
N-acetyltransferase 8B

1

0

High-throughput

0.279

Low

450178

TBC3G
TBC1 domain family member 3G

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025