Protein: SKAP
Small kinetochore-associated protein (SKAP) (Kinetochore-localized astrin-binding protein) (Kinastrin) (Kinetochore-localized astrin/SPAG5-binding protein) (TRAF4-associated factor 1)

Gene: SKAP, KNSTRN
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q9Y448

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000226 - microtubule cytoskeleton organization
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0001726 - ruffle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1152311

MARE1
Microtubule-associated protein RP/EB family member 1

5

1

High-throughput

0.717

High

1462085

PRP19
Pre-mRNA-processing factor 19

6

0

Small-scale

0.702

High

991783

DYL1
Dynein light chain 1, cytoplasmic

4

1

High-throughput

0.697

High

1389714

SGF29
SAGA-associated factor 29

5

0

High-throughput

0.687

High

1462636

MARE3
Microtubule-associated protein RP/EB family member 3

3

1

High-throughput

0.653

High

1390763

DYL2
Dynein light chain 2, cytoplasmic

3

1

High-throughput

0.650

High

1053444

DEUP1
Deuterosome assembly protein 1

3

0

High-throughput

0.638

High

1451186

IFT57
Intraflagellar transport protein 57 homolog

3

0

High-throughput

0.638

High

50947

SYCE3
Synaptonemal complex central element protein 3

3

0

High-throughput

0.634

High

239258

ZNRD2
Protein ZNRD2

3

0

High-throughput

0.634

High

1396990

IFT74
Intraflagellar transport protein 74 homolog

3

0

High-throughput

0.634

High

1392372

BORC6
BLOC-1-related complex subunit 6

4

1

High-throughput

0.633

High

1331750

CCD89
Coiled-coil domain-containing protein 89

2

1

High-throughput

0.628

High

273124

CLU
Clustered mitochondria protein homolog

2

1

High-throughput

0.611

High

281124

TACC1
Transforming acidic coiled-coil-containing protein 1

2

0

High-throughput

0.602

High

1437209

CSN7B
COP9 signalosome complex subunit 7b

2

0

High-throughput

0.602

High

1143607

PCM1
Pericentriolar material 1 protein

2

0

High-throughput

0.585

High

1410084

USB1
U6 snRNA phosphodiesterase 1

2

0

High-throughput

0.585

High

217229

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

248804

PEPL
Periplakin

2

0

High-throughput

0.580

High

1313727

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.580

High

1417607

BEX2
Protein BEX2

2

0

High-throughput

0.580

High

1452534

ABI2
Abl interactor 2

2

0

High-throughput

0.580

High

1404076

MYCBP
c-Myc-binding protein

2

0

High-throughput

0.576

High

920392

PLK1
Serine/threonine-protein kinase PLK1

2

0

High-throughput

0.559

High

1123886

DCTN1
Dynactin subunit 1

2

0

High-throughput

0.559

High

248163

NUPR1
Nuclear protein 1

2

0

Small-scale

0.551

High

180970

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.536

High

323623

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.536

High

340270

PCNT
Pericentrin

1

1

High-throughput

0.536

High

535703

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.536

High

415957

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

128494

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.513

High

155219

NCKP5
Nck-associated protein 5

1

0

High-throughput

0.513

High

272778

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

0

High-throughput

0.513

High

893585

GBG10

1

0

High-throughput

0.513

High

1132655

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.513

High

1228583

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.513

High

1271956

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.513

High

1401194

SPAG5
Sperm-associated antigen 5

1

0

High-throughput

0.513

High

1402934

CK5P2
CDK5 regulatory subunit-associated protein 2

1

0

High-throughput

0.513

High

1420594

TRIM4
E3 ubiquitin-protein ligase TRIM4

1

0

High-throughput

0.513

High

1432965

SRMS
Tyrosine-protein kinase Srms

1

0

High-throughput

0.513

High

1438473

LPAR2
Lysophosphatidic acid receptor 2

1

0

High-throughput

0.513

High

1458427

COMD3
COMM domain-containing protein 3

1

0

High-throughput

0.513

High

844124

HD
Huntingtin

1

0

High-throughput

0.493

High

1201174

CCD93
Coiled-coil domain-containing protein 93

1

1

High-throughput

0.489

High

1161276

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.486

High

1273188

CHM1B
Charged multivesicular body protein 1b

1

0

High-throughput

0.486

High

538164

HSP7C
Heat shock cognate 71 kDa protein

1

1

Small-scale

0.479

High

600968

HSP76
Heat shock 70 kDa protein 6

1

1

Small-scale

0.479

High

1446850

TRI36
E3 ubiquitin-protein ligase TRIM36

1

2

High-throughput

0.479

High

533803

CLUS
Clusterin

1

0

Small-scale

0.460

High

1040954

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.460

High

1453647

PALS2
Protein PALS2

1

0

High-throughput

0.460

High

243377

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

279002

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

401754

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

437399

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

786953

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.458

High

872930

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

887375

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

942978

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1005999

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

1024958

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1065792

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

0

High-throughput

0.458

High

1089371

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

0

High-throughput

0.458

High

1141096

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1322476

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

1326395

NIN
Ninein

1

0

High-throughput

0.458

High

1421236

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1434313

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1405179

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.438

High

1448588

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1335795

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

1491160

WASC3
WASH complex subunit 3

2

0

High-throughput

0.316

High

1307683

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

257201

CCD22
Coiled-coil domain-containing protein 22

1

0

High-throughput

0.279

Low

1234634

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.279

Low

1389095

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.279

Low

1410555

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1431025

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1490513

ANGP4
Angiopoietin-4

1

0

High-throughput

0.279

Low

1211046

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.249

Low

1339774

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

1167135

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025