Protein: CLC14
C-type lectin domain family 14 member A (Epidermal growth factor receptor 5) (EGFR-5)

Gene: CLC14, CLEC14A
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q86T13

Gene Ontology (top 5):
GO:0001946 - lymphangiogenesis
GO:0002042 - cell migration involved in sprouting angiogenesis
GO:0009897 - external side of plasma membrane
GO:0016477 - cell migration
GO:0030246 - carbohydrate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549454

CD20
B-lymphocyte antigen CD20

2

0

High-throughput

0.580

High

1280986

PXK
PX domain-containing protein kinase-like protein

2

6

High-throughput

0.574

High

154495

CLD4
Claudin-4

2

2

High-throughput

0.553

High

252609

TSN2
Tetraspanin-2

2

7

High-throughput

0.553

High

692221

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

2

High-throughput

0.553

High

1030368

PMP22
Peripheral myelin protein 22

2

3

High-throughput

0.553

High

1092780

MALL
MAL-like protein

2

1

High-throughput

0.553

High

1154665

VAMP3
Vesicle-associated membrane protein 3

2

1

High-throughput

0.553

High

1286731

CLD19
Claudin-19

2

2

High-throughput

0.553

High

1286729

CLC14
C-type lectin domain family 14 member A

1

13

Small-scale

0.501

High

537432

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.489

High

690098

AVR2A
Activin receptor type-2A

1

1

High-throughput

0.489

High

905605

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.489

High

1286734

MROH1
Maestro heat-like repeat-containing protein family member 1

1

1

High-throughput

0.489

High

1286735

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.489

High

1286745

MTNA
Methylthioribose-1-phosphate isomerase

1

2

High-throughput

0.489

High

1286746

OSBL8
Oxysterol-binding protein-related protein 8

1

1

High-throughput

0.489

High

1286759

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

1

High-throughput

0.489

High

389431

FINC
Fibronectin

1

15

Small-scale

0.479

High

535862

LAMC1
Laminin subunit gamma-1

1

8

Small-scale

0.479

High

698828

CALX
Calnexin

1

10

Small-scale

0.479

High

1022548

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

5

Small-scale

0.479

High

1157278

LAMA4
Laminin subunit alpha-4

1

10

Small-scale

0.479

High

1286748

MMRN2
Multimerin-2

1

15

Small-scale

0.479

High

251928

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

Small-scale

0.458

High

135261

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

5

Small-scale

0.437

High

135645

DNM1L
Dynamin-1-like protein

1

1

Small-scale

0.437

High

436920

K1C18
Keratin, type I cytoskeletal 18

1

4

Small-scale

0.437

High

474788

VIME
Vimentin

1

1

Small-scale

0.437

High

535248

BIP
Endoplasmic reticulum chaperone BiP

1

9

Small-scale

0.437

High

854681

RAGP1
Ran GTPase-activating protein 1

1

1

Small-scale

0.437

High

875703

PRC2A
Protein PRRC2A

1

2

Small-scale

0.437

High

900008

FXR1
RNA-binding protein FXR1

1

5

Small-scale

0.437

High

900393

FXR2
RNA-binding protein FXR2

1

5

Small-scale

0.437

High

1056824

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

Small-scale

0.437

High

1126461

CAPR1
Caprin-1

1

1

Small-scale

0.437

High

1148302

CNN3
Calponin-3

1

1

Small-scale

0.437

High

1152538

ELAV1
ELAV-like protein 1

1

2

Small-scale

0.437

High

1164446

MIC60
MICOS complex subunit MIC60

1

1

Small-scale

0.437

High

1286730

DJC10
DnaJ homolog subfamily C member 10

1

4

Small-scale

0.437

High

1286738

DDX1
ATP-dependent RNA helicase DDX1

1

1

Small-scale

0.437

High

1286742

FUBP3
Far upstream element-binding protein 3

1

4

Small-scale

0.437

High

1286752

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

4

Small-scale

0.437

High

1286755

TBK1
Serine/threonine-protein kinase TBK1

1

3

Small-scale

0.437

High

1286756

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

Small-scale

0.437

High

1286760

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

4

Small-scale

0.437

High

1286739

LDAF1
Lipid droplet assembly factor 1

2

0

High-throughput

0.328

High

1286751

INT7
Integrator complex subunit 7

2

0

High-throughput

0.328

High

1286757

TCAF1
TRPM8 channel-associated factor 1

2

0

High-throughput

0.328

High

156560

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.316

High

894860

EMD
Emerin

2

0

High-throughput

0.316

High

1286736

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

1286743

MGST2
Microsomal glutathione S-transferase 2

2

0

High-throughput

0.316

High

1286744

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

341255

ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase

1

0

High-throughput

0.279

Low

1103555

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

0

High-throughput

0.279

Low

1229496

C19L1
CWF19-like protein 1

1

0

High-throughput

0.279

Low

1231432

ATLA3
Atlastin-3

1

0

High-throughput

0.279

Low

1243307

INT5
Integrator complex subunit 5

1

0

High-throughput

0.279

Low

1277727

TMC6
Transmembrane channel-like protein 6

1

0

High-throughput

0.279

Low

1286733

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.279

Low

1286737

PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

1

0

High-throughput

0.279

Low

1286741

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

1286749

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.279

Low

286232

CSDE1
Cold shock domain-containing protein E1

1

0

Small-scale

0.249

Low

324964

HEXI1
Protein HEXIM1

1

0

Small-scale

0.249

Low

329299

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

Small-scale

0.249

Low

370326

CYTA
Cystatin-A

1

0

Small-scale

0.249

Low

610391

PRS6A
26S proteasome regulatory subunit 6A

1

0

Small-scale

0.249

Low

701052

PSB6
Proteasome subunit beta type-6

1

0

Small-scale

0.249

Low

807481

IF4A3
Eukaryotic initiation factor 4A-III

1

0

Small-scale

0.249

Low

903617

GALK1
Galactokinase

1

0

Small-scale

0.249

Low

984839

RL31
Large ribosomal subunit protein eL31

1

0

Small-scale

0.249

Low

1058875

ZO1
Tight junction protein 1

1

0

Small-scale

0.249

Low

1102006

PABP4
Polyadenylate-binding protein 4

1

0

Small-scale

0.249

Low

1143730

PON2
Serum paraoxonase/arylesterase 2

1

0

Small-scale

0.249

Low

1160673

DREB
Drebrin

1

0

Small-scale

0.249

Low

1277835

NUFP2
FMR1-interacting protein NUFIP2

1

0

Small-scale

0.249

Low

1286732

FA98A
Protein FAM98A

1

0

Small-scale

0.249

Low

1286740

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

Small-scale

0.249

Low

1286747

TDRD3
Tudor domain-containing protein 3

1

0

Small-scale

0.249

Low

1286750

STRN4
Striatin-4

1

0

Small-scale

0.249

Low

1286753

SELN
Selenoprotein N

1

0

Small-scale

0.249

Low

1286754

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

Small-scale

0.249

Low

1286758

SNX9
Sorting nexin-9

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025