Protein: PKNX2
Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2)

Gene: PKNX2, PKNOX2
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q96KN3

Gene Ontology (top 5):
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003785 - actin monomer binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

253023

LMX1B
LIM homeobox transcription factor 1-beta

3

8

High-throughput

0.861

High

823858

PBX1
Pre-B-cell leukemia transcription factor 1

2

20

High-throughput

0.783

High

1396171

PBX4
Pre-B-cell leukemia transcription factor 4

3

20

High-throughput

0.768

High

823906

PBX2
Pre-B-cell leukemia transcription factor 2

1

19

High-throughput

0.691

High

139407

VMA5A
von Willebrand factor A domain-containing protein 5A

2

5

High-throughput

0.628

High

1315505

DAAF8
Dynein axonemal assembly factor 8

2

5

High-throughput

0.628

High

823973

PBX3
Pre-B-cell leukemia transcription factor 3

1

20

High-throughput

0.618

High

63251

VP37C
Vacuolar protein sorting-associated protein 37C

2

4

High-throughput

0.606

High

291855

STK16
Serine/threonine-protein kinase 16

2

3

High-throughput

0.606

High

352224

MBD3
Methyl-CpG-binding domain protein 3

2

1

High-throughput

0.606

High

873992

NRIP1
Nuclear receptor-interacting protein 1

2

1

High-throughput

0.606

High

920595

ARFP2
Arfaptin-2

2

3

High-throughput

0.606

High

1123080

FHL2
Four and a half LIM domains protein 2

2

3

High-throughput

0.606

High

1315682

CC116
Coiled-coil domain-containing protein 116

2

1

High-throughput

0.606

High

1390144

MCRS1
Microspherule protein 1

2

1

High-throughput

0.606

High

1392031

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

2

High-throughput

0.606

High

1396166

TRIB3
Tribbles homolog 3

2

1

High-throughput

0.606

High

1396172

ENKD1
Enkurin domain-containing protein 1

2

1

High-throughput

0.606

High

1396175

PICK1
PRKCA-binding protein

2

3

High-throughput

0.606

High

1396177

CT2NL
CTTNBP2 N-terminal-like protein

2

3

High-throughput

0.606

High

862940

IQGA1
Ras GTPase-activating-like protein IQGAP1

2

0

High-throughput

0.580

High

1234734

CENPP
Centromere protein P

2

0

High-throughput

0.580

High

1396167

TS101
Tumor susceptibility gene 101 protein

2

0

High-throughput

0.580

High

1396169

DDA1
DET1- and DDB1-associated protein 1

2

0

High-throughput

0.580

High

1396173

CSTFT
Cleavage stimulation factor subunit 2 tau variant

2

0

High-throughput

0.580

High

1396174

PAAT
ATPase PAAT

2

0

High-throughput

0.580

High

1280017

CE024
UPF0461 protein C5orf24

2

5

High-throughput

0.574

High

1392974

CC120
Coiled-coil domain-containing protein 120

2

6

High-throughput

0.574

High

169706

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

3

High-throughput

0.553

High

1330058

USBP1
Harmonin-binding protein USHBP1

2

2

High-throughput

0.553

High

1349467

F110B
Protein FAM110B

2

3

High-throughput

0.553

High

1362028

CTTB2
Cortactin-binding protein 2

2

3

High-throughput

0.553

High

1396168

NUP58
Nucleoporin p58/p45

2

3

High-throughput

0.553

High

1196297

GRAP1
GRIP1-associated protein 1

1

3

High-throughput

0.536

High

1395450

MY15B
Unconventional myosin-XVB

1

2

High-throughput

0.515

High

862382

YAP1
Transcriptional coactivator YAP1

1

4

High-throughput

0.501

High

1396176

BMP2K
BMP-2-inducible protein kinase

1

3

Small-scale

0.494

High

370759

FOS
Protein c-Fos

1

3

High-throughput

0.479

High

1114016

CUL3
Cullin-3

1

1

High-throughput

0.479

High

4794

A0A1B0GWI1
Coiled-coil domain containing 196

1

1

High-throughput

0.470

High

251283

CRBL2
cAMP-responsive element-binding protein-like 2

2

0

High-throughput

0.316

High

1276145

NUP54
Nucleoporin p54

2

0

High-throughput

0.316

High

1330168

CC185
Coiled-coil domain-containing protein 185

2

0

High-throughput

0.316

High

1346690

CA216
UPF0500 protein C1orf216

2

0

High-throughput

0.316

High

883132

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.279

Low

1396170

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025