Protein: GLIS2
Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein)

Gene: GLIS2
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9BZE0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

204429

MS18B
Protein Mis18-beta

2

1

High-throughput

0.783

High

1317818

WNK1
Serine/threonine-protein kinase WNK1

1

7

Small-scale

0.698

High

882542

BCAR1
Breast cancer anti-estrogen resistance protein 1

3

2

Small-scale

0.677

High

374830

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.647

High

515502

CDK4
Cyclin-dependent kinase 4

1

9

High-throughput

0.647

High

585931

WT1
Wilms tumor protein

1

19

High-throughput

0.647

High

682014

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

High-throughput

0.647

High

805469

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

13

High-throughput

0.647

High

854740

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

13

High-throughput

0.647

High

960243

CDK6
Cyclin-dependent kinase 6

1

8

High-throughput

0.647

High

1026829

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

13

High-throughput

0.647

High

1079148

STK11
Serine/threonine-protein kinase STK11

1

4

High-throughput

0.647

High

1239690

GLIS1
Zinc finger protein GLIS1

1

18

High-throughput

0.647

High

1305588

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

12

High-throughput

0.647

High

1317817

GLIS2
Zinc finger protein GLIS2

1

18

High-throughput

0.647

High

1317821

LATS2
Serine/threonine-protein kinase LATS2

1

4

High-throughput

0.647

High

174018

SHOX
Short stature homeobox protein

2

8

High-throughput

0.606

High

197821

CRX
Cone-rod homeobox protein

2

11

High-throughput

0.606

High

308132

VENTX
Homeobox protein VENTX

2

17

High-throughput

0.606

High

862634

FOSB
Protein FosB

2

4

High-throughput

0.606

High

881277

CTBP2
C-terminal-binding protein 2

2

4

High-throughput

0.606

High

882982

RBM11
Splicing regulator RBM11

2

5

High-throughput

0.606

High

944087

PO6F2
POU domain, class 6, transcription factor 2

2

13

High-throughput

0.606

High

974409

CREM
cAMP-responsive element modulator

2

6

High-throughput

0.606

High

978243

ARI5A
AT-rich interactive domain-containing protein 5A

2

3

High-throughput

0.606

High

993587

TLE5
TLE family member 5

2

4

High-throughput

0.606

High

1261465

TWST2
Twist-related protein 2

2

6

High-throughput

0.606

High

1274230

RBPMS
RNA-binding protein with multiple splicing

2

1

High-throughput

0.606

High

1317823

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.606

High

1317825

PKHB1
Pleckstrin homology domain-containing family B member 1

2

1

High-throughput

0.606

High

1317826

ZRAN1
Ubiquitin thioesterase ZRANB1

2

5

High-throughput

0.606

High

1317829

NDK7
Nucleoside diphosphate kinase homolog 7

2

1

High-throughput

0.606

High

717327

CTNB1
Catenin beta-1

1

12

Small-scale

0.592

High

267187

GEMI
Geminin

2

0

High-throughput

0.580

High

901737

PFD3
Prefoldin subunit 3

2

0

High-throughput

0.580

High

931844

CSK2B
Casein kinase II subunit beta

2

0

High-throughput

0.580

High

1124840

ACTMP
Actin maturation protease

2

0

High-throughput

0.580

High

1023328

TRI32
E3 ubiquitin-protein ligase TRIM32

1

14

Small-scale

0.561

High

49973

F168B
Myelin-associated neurite-outgrowth inhibitor

2

1

High-throughput

0.553

High

62416

GG6L9
Golgin subfamily A member 6-like protein 9

2

17

High-throughput

0.553

High

679305

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

4

High-throughput

0.553

High

993288

ACTN3
Alpha-actinin-3

2

4

High-throughput

0.553

High

997458

VAC14
Protein VAC14 homolog

2

4

High-throughput

0.553

High

1109156

KRA61
Keratin-associated protein 6-1

2

2

High-throughput

0.553

High

1109257

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.553

High

1109468

KR195
Keratin-associated protein 19-5

2

1

High-throughput

0.553

High

1110434

KR197
Keratin-associated protein 19-7

2

1

High-throughput

0.553

High

1205878

GPSM1
G-protein-signaling modulator 1

2

7

High-throughput

0.553

High

1216049

KRA81
Keratin-associated protein 8-1

2

1

High-throughput

0.553

High

1231750

AN36B
Ankyrin repeat domain-containing protein 36B

2

6

High-throughput

0.553

High

1287266

PKHB2
Pleckstrin homology domain-containing family B member 2

2

1

High-throughput

0.553

High

198979

RFOX2
RNA binding protein fox-1 homolog 2

1

4

Small-scale

0.541

High

641925

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

Small-scale

0.541

High

946376

GPSM2
G-protein-signaling modulator 2

1

7

Small-scale

0.541

High

1014196

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

3

Small-scale

0.541

High

1148962

CYTSA
Cytospin-A

1

3

Small-scale

0.541

High

1317819

SYF1
Pre-mRNA-splicing factor SYF1

1

3

Small-scale

0.541

High

301496

WDR47
WD repeat-containing protein 47

1

1

High-throughput

0.536

High

1050768

FHL2
Four and a half LIM domains protein 2

1

19

High-throughput

0.536

High

1317820

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

2

High-throughput

0.536

High

1317824

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

1

High-throughput

0.536

High

169306

MDM4
Protein Mdm4

1

2

High-throughput

0.501

High

347826

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.501

High

383964

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

4

High-throughput

0.501

High

441562

MET
Hepatocyte growth factor receptor

1

4

High-throughput

0.501

High

443243

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.501

High

488798

ARAF
Serine/threonine-protein kinase A-Raf

1

2

High-throughput

0.501

High

536141

HGF
Hepatocyte growth factor

1

1

High-throughput

0.501

High

624609

CCNE1
G1/S-specific cyclin-E1

1

2

High-throughput

0.501

High

643589

PTBP1
Polypyrimidine tract-binding protein 1

1

6

High-throughput

0.501

High

649155

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

2

High-throughput

0.501

High

673102

CCND2
G1/S-specific cyclin-D2

1

3

High-throughput

0.501

High

719606

MERL
Merlin

1

6

High-throughput

0.501

High

782200

SOX3
Transcription factor SOX-3

1

20

High-throughput

0.501

High

787302

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

3

High-throughput

0.501

High

790871

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

6

High-throughput

0.501

High

790945

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

4

High-throughput

0.501

High

962958

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

High-throughput

0.501

High

1075250

TEAD2
Transcriptional enhancer factor TEF-4

1

2

High-throughput

0.501

High

1085665

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

High-throughput

0.501

High

1317718

NSD3
Histone-lysine N-methyltransferase NSD3

1

4

High-throughput

0.501

High

1317822

RASF1
Ras association domain-containing protein 1

1

1

High-throughput

0.501

High

1317828

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.501

High

240792

USO1
General vesicular transport factor p115

1

3

High-throughput

0.489

High

864001

CLH2
Clathrin heavy chain 2

1

1

High-throughput

0.489

High

1267539

TSC1
Hamartin

1

9

High-throughput

0.481

High

154054

TERT
Telomerase reverse transcriptase

1

0

High-throughput

0.480

High

1054195

BECN1
Beclin-1

1

0

High-throughput

0.480

High

668959

PML
Protein PML

1

20

Small-scale

0.479

High

953047

PR20D
Proline-rich protein 20D

1

1

High-throughput

0.470

High

1162268

Q6PJH3
A kinase

1

1

High-throughput

0.470

High

1203632

Q86WV8
TSC complex subunit 1

1

4

High-throughput

0.470

High

1294571

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.460

High

608111

FGFR4
Fibroblast growth factor receptor 4

1

7

High-throughput

0.457

High

665327

EPHA2
Ephrin type-A receptor 2

1

8

High-throughput

0.457

High

1032601

CTBP1
C-terminal-binding protein 1

1

4

High-throughput

0.445

High

953120

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

1307563

AKAP9
A-kinase anchor protein 9

1

4

High-throughput

0.439

High

1190800

KR193
Keratin-associated protein 19-3

2

0

High-throughput

0.316

High

555189

CD44
CD44 antigen

1

0

High-throughput

0.261

Low

1317827

CBLC
E3 ubiquitin-protein ligase CBL-C

1

0

High-throughput

0.261

Low

1244839

BBS1
Bardet-Biedl syndrome 1 protein

1

0

Small-scale

0.249

Low

1315205

BBS2
Bardet-Biedl syndrome 2 protein

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024