Protein: RREB1
Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1)

Gene: RREB1
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q92766

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001650 - fibrillar center

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1109952

HDAC1
Histone deacetylase 1

7

7

High-throughput

0.749

High

1103299

CTBP1
C-terminal-binding protein 1

5

2

Small-scale

0.714

High

1351843

NEK7
Serine/threonine-protein kinase Nek7

1

4

High-throughput

0.691

High

1367999

HDAC2
Histone deacetylase 2

3

7

High-throughput

0.675

High

246825

KDM1A
Lysine-specific histone demethylase 1A

4

2

Small-scale

0.672

High

157695

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.618

High

339812

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.618

High

538446

EGR2
E3 SUMO-protein ligase EGR2

1

19

High-throughput

0.618

High

944712

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.618

High

1368005

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.618

High

1368019

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.618

High

1368015

RCOR1
REST corepressor 1

2

0

High-throughput

0.585

High

474165

NFIC
Nuclear factor 1 C-type

2

14

High-throughput

0.584

High

1133566

NFIX
Nuclear factor 1 X-type

2

14

High-throughput

0.584

High

188328

HDAC3
Histone deacetylase 3

1

7

High-throughput

0.554

High

166182

AIM2
Interferon-inducible protein AIM2

1

1

High-throughput

0.536

High

1163104

H2B2E
Histone H2B type 2-E

1

3

High-throughput

0.536

High

1235484

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.536

High

1332557

TEX19
Testis-expressed protein 19

1

2

High-throughput

0.536

High

1368007

ARL6
ADP-ribosylation factor-like protein 6

1

1

High-throughput

0.536

High

791593

SYUA
Alpha-synuclein

1

0

High-throughput

0.513

High

920709

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

0

High-throughput

0.513

High

933041

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.513

High

1324574

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.513

High

1368014

SMBT1
Scm-like with four MBT domains protein 1

1

0

High-throughput

0.513

High

964396

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

1161971

H31T
Histone H3.1t

1

16

Small-scale

0.501

High

1241714

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.493

High

347217

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

143151

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

210070

CRX
Cone-rod homeobox protein

1

5

High-throughput

0.479

High

414329

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

485302

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

4

High-throughput

0.479

High

487595

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

520243

ANDR
Androgen receptor

1

14

Small-scale

0.479

High

662257

PAX7
Paired box protein Pax-7

1

3

High-throughput

0.479

High

685287

PAX6
Paired box protein Pax-6

1

3

High-throughput

0.479

High

696102

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

725294

TLX1
T-cell leukemia homeobox protein 1

1

6

High-throughput

0.479

High

800019

COIL
Coilin

1

3

High-throughput

0.479

High

834004

HNF4A
Hepatocyte nuclear factor 4-alpha

1

7

High-throughput

0.479

High

837074

ELK3
ETS domain-containing protein Elk-3

1

3

High-throughput

0.479

High

879322

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

883642

CENPA
Histone H3-like centromeric protein A

1

16

High-throughput

0.479

High

887068

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

895766

LHX2
LIM/homeobox protein Lhx2

1

4

High-throughput

0.479

High

942457

GSC
Homeobox protein goosecoid

1

11

High-throughput

0.479

High

980075

H4
Histone H4

1

3

High-throughput

0.479

High

980977

H2B1C
Histone H2B type 1-C/E/F/G/I

1

3

High-throughput

0.479

High

998625

H31
Histone H3.1

1

16

High-throughput

0.479

High

1017072

H33
Histone H3.3

1

16

High-throughput

0.479

High

1025940

NDP
Norrin

1

1

Small-scale

0.479

High

1045591

TF65
Transcription factor p65

1

3

High-throughput

0.479

High

1087902

NFIA
Nuclear factor 1 A-type

1

14

High-throughput

0.479

High

1097461

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1149150

SF3A1
Splicing factor 3A subunit 1

1

1

High-throughput

0.479

High

1313307

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1368001

PF21A
PHD finger protein 21A

1

10

High-throughput

0.479

High

1368002

CIC
Protein capicua homolog

1

4

High-throughput

0.479

High

1368003

FEV
Protein FEV

1

3

High-throughput

0.479

High

1368004

SOX7
Transcription factor SOX-7

1

3

High-throughput

0.479

High

1368011

VSX1
Visual system homeobox 1

1

6

High-throughput

0.479

High

1368012

ZMYM2
Zinc finger MYM-type protein 2

1

1

High-throughput

0.479

High

1368013

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1368016

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

10

High-throughput

0.479

High

1368018

ZN330
Zinc finger protein 330

1

6

High-throughput

0.479

High

191033

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

651092

RFX1
MHC class II regulatory factor RFX1

1

0

High-throughput

0.458

High

697206

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

703178

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

1276575

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1325188

HROB
Homologous recombination OB-fold protein

1

0

Small-scale

0.458

High

1368006

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1368009

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1368017

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

991386

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.445

High

1368010

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

318840

RHBT1
Rho-related BTB domain-containing protein 1

1

2

High-throughput

0.437

High

768796

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1347799

SPT20
Spermatogenesis-associated protein 20

2

0

High-throughput

0.328

High

1311821

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.249

Low

1368000

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1368008

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025