Protein: MCM9
DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9)

Gene: MCM9
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q9NXL9

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0003678 - DNA helicase activity
GO:0003682 - chromatin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1452062

MCM8
DNA helicase MCM8

8

19

Small-scale

0.967

High

846682

MSH2
DNA mismatch repair protein Msh2

4

4

Small-scale

0.694

High

756071

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.691

High

827501

MLH1
DNA mismatch repair protein Mlh1

3

5

Small-scale

0.656

High

913413

MSH6
DNA mismatch repair protein Msh6

3

4

Small-scale

0.656

High

1042667

UPAR
Urokinase plasminogen activator surface receptor

3

0

High-throughput

0.638

High

1358675

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

2

5

High-throughput

0.628

High

1432788

NELFA
Negative elongation factor A

2

4

High-throughput

0.628

High

1452060

MCM9
DNA helicase MCM9

1

19

Small-scale

0.618

High

888487

TSP3
Thrombospondin-3

3

3

High-throughput

0.609

High

138327

PSDE
26S proteasome non-ATPase regulatory subunit 14

2

5

Small-scale

0.584

High

633345

MSH3
DNA mismatch repair protein Msh3

2

4

Small-scale

0.584

High

769790

RFC4
Replication factor C subunit 4

2

5

Small-scale

0.584

High

769914

RFC2
Replication factor C subunit 2

2

5

Small-scale

0.584

High

829166

RFC5
Replication factor C subunit 5

2

5

Small-scale

0.584

High

829280

RFC3
Replication factor C subunit 3

2

5

Small-scale

0.584

High

838802

MTREX
Exosome RNA helicase MTR4

2

8

Small-scale

0.584

High

928667

PMS1
PMS1 protein homolog 1

2

5

Small-scale

0.584

High

1032558

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

2

5

Small-scale

0.584

High

1160843

NFIL3
Nuclear factor interleukin-3-regulated protein

2

11

Small-scale

0.584

High

1293235

HORM1
HORMA domain-containing protein 1

2

2

Small-scale

0.584

High

1402258

WRIP1
ATPase WRNIP1

2

7

Small-scale

0.584

High

1430394

DDX47
Probable ATP-dependent RNA helicase DDX47

2

8

Small-scale

0.584

High

1452066

RUVB1
RuvB-like 1

2

2

Small-scale

0.584

High

1452068

SF3B6
Splicing factor 3B subunit 6

2

6

Small-scale

0.584

High

139421

VMA5A
von Willebrand factor A domain-containing protein 5A

2

1

High-throughput

0.574

High

1452065

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

4

High-throughput

0.574

High

1420402

API5
Apoptosis inhibitor 5

2

0

Small-scale

0.559

High

1386391

FAF2
FAS-associated factor 2

2

6

High-throughput

0.558

High

1291241

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

1330474

HORM2
HORMA domain-containing protein 2

1

2

High-throughput

0.536

High

1413471

MCMBP
Mini-chromosome maintenance complex-binding protein

1

20

High-throughput

0.536

High

141144

NOP56
Nucleolar protein 56

2

2

Small-scale

0.533

High

1452067

NOP58
Nucleolar protein 58

2

2

Small-scale

0.533

High

1325199

HROB
Homologous recombination OB-fold protein

1

1

Small-scale

0.515

High

1452063

PNMA2
Paraneoplastic antigen Ma2

1

9

High-throughput

0.489

High

839388

MTOR
Serine/threonine-protein kinase mTOR

1

11

High-throughput

0.479

High

1055983

RAD51
DNA repair protein RAD51 homolog 1

1

3

Small-scale

0.479

High

1314448

SLX4
Structure-specific endonuclease subunit SLX4

1

12

High-throughput

0.479

High

1369786

RAD50
DNA repair protein RAD50

1

20

Small-scale

0.479

High

1452061

XPO7
Exportin-7

1

5

High-throughput

0.479

High

262138

NBN
Nibrin

1

0

Small-scale

0.458

High

892955

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

1251456

GGYF2
GRB10-interacting GYF protein 2

1

15

High-throughput

0.437

High

1452064

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

High-throughput

0.437

High

1131242

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

847796

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

1219249

CHIC1
Cysteine-rich hydrophobic domain-containing protein 1

1

0

High-throughput

0.279

Low

1338051

WFD11
Protein WFDC11

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025