Protein: PAXX
Protein PAXX (Paralog of XRCC4 and XLF) (XRCC4-like small protein)

Gene: PAXX
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q9BUH6

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

523979

XRCC6
X-ray repair cross-complementing protein 6

4

1

Small-scale

0.694

High

1312864

PAXX
Protein PAXX

1

0

Small-scale

0.679

High

525043

XRCC5
X-ray repair cross-complementing protein 5

3

1

Small-scale

0.657

High

273478

PPM1B
Protein phosphatase 1B

2

0

High-throughput

0.602

High

1033972

XRCC4
DNA repair protein XRCC4

2

0

Small-scale

0.559

High

944402

PRKDC
DNA-dependent protein kinase catalytic subunit

2

0

Small-scale

0.547

High

422634

GPX1
Glutathione peroxidase 1

1

1

High-throughput

0.536

High

879783

DLX6
Homeobox protein DLX-6

1

1

High-throughput

0.536

High

311830

TACC2
Transforming acidic coiled-coil-containing protein 2

1

0

High-throughput

0.513

High

616661

GCSH
Glycine cleavage system H protein, mitochondrial

1

0

High-throughput

0.513

High

751805

GRP75
Stress-70 protein, mitochondrial

1

0

High-throughput

0.513

High

978879

TF65
Transcription factor p65

1

0

High-throughput

0.513

High

980998

EMX2
Homeobox protein EMX2

1

0

High-throughput

0.513

High

1050624

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

0

High-throughput

0.513

High

1170191

RBPS2
RNA-binding protein with multiple splicing 2

1

0

High-throughput

0.513

High

1185282

VASH1
Tubulinyl-Tyr carboxypeptidase 1

1

0

High-throughput

0.513

High

1306863

FOXB1
Forkhead box protein B1

1

0

High-throughput

0.513

High

1312866

ROP1A
Ropporin-1A

1

0

High-throughput

0.513

High

1312867

MA2C1
Alpha-mannosidase 2C1

1

0

High-throughput

0.513

High

1287356

OPTN
Optineurin

1

0

High-throughput

0.493

High

1302290

GPX7
Glutathione peroxidase 7

1

1

High-throughput

0.489

High

395638

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

894373

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

1067117

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.458

High

1171497

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1243910

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1312865

CYREN
Cell cycle regulator of non-homologous end joining

1

0

Small-scale

0.458

High

836875

DNLI4
DNA ligase 4

1

0

Small-scale

0.426

High

566035

INAR1
Interferon alpha/beta receptor 1

1

0

High-throughput

0.279

Low

661417

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1236190

IQCF1
IQ domain-containing protein F1

1

0

High-throughput

0.279

Low

1252865

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

129829

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.249

Low

484904

GAGE1
G antigen 1

1

0

High-throughput

0.232

Low

887945

CD81
CD81 antigen

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024