Protein: SMAP
Small acidic protein

Gene: SMAP
Organism: Homo sapiens
Interactions: 64
UniProt ID: O00193

Gene Ontology (top 5):

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

125955

MARK2
Serine/threonine-protein kinase MARK2

1

1

High-throughput

0.489

High

125938

SHC1
SHC-transforming protein 1

1

1

High-throughput

0.464

High

125916

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.437

High

125917

H2B1K
Histone H2B type 1-K

1

4

High-throughput

0.437

High

125921

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

2

High-throughput

0.437

High

125927

H2B1J
Histone H2B type 1-J

1

4

High-throughput

0.437

High

125928

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.437

High

125942

H2B1D
Histone H2B type 1-D

1

4

High-throughput

0.437

High

125946

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

2

High-throughput

0.437

High

125949

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.437

High

125966

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

2

High-throughput

0.437

High

125967

H2B1H
Histone H2B type 1-H

1

4

High-throughput

0.437

High

125969

H2B1L
Histone H2B type 1-L

1

4

High-throughput

0.437

High

125923

A2MG
Alpha-2-macroglobulin

2

0

High-throughput

0.307

High

125941

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

0

High-throughput

0.298

High

125961

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.279

Low

125919

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.265

Low

125926

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.265

Low

125929

ZBT48
Zinc finger and BTB domain-containing protein 48

1

0

High-throughput

0.265

Low

125933

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.265

Low

125934

PTN
Pleiotrophin

1

0

High-throughput

0.265

Low

125936

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.265

Low

125948

TRA2A
Transformer-2 protein homolog alpha

1

0

High-throughput

0.265

Low

125950

MBTP1
Membrane-bound transcription factor site-1 protease

1

0

High-throughput

0.265

Low

125954

FBN3
Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide]

1

0

High-throughput

0.265

Low

125962

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.265

Low

125973

RN19A
E3 ubiquitin-protein ligase RNF19A

1

0

High-throughput

0.265

Low

125975

SEM5B
Semaphorin-5B

1

0

High-throughput

0.265

Low

125976

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.265

Low

125977

SNCAP
Synphilin-1

1

0

High-throughput

0.265

Low

125914

AURKA
Aurora kinase A

1

0

High-throughput

0.249

Low

125918

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

125920

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

125922

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

Small-scale

0.249

Low

125924

RASK
GTPase KRas

1

0

High-throughput

0.249

Low

125925

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

125930

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.249

Low

125931

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

125932

NELFE
Negative elongation factor E

1

0

High-throughput

0.249

Low

125935

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.249

Low

125937

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

125939

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

125943

EWS
RNA-binding protein EWS

1

0

High-throughput

0.249

Low

125944

TF65
Transcription factor p65

1

0

High-throughput

0.249

Low

125945

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.249

Low

125947

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.249

Low

125951

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

125952

DUS5
Dual specificity protein phosphatase 5

1

0

High-throughput

0.249

Low

125953

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

125956

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

125957

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.249

Low

125958

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

125963

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.249

Low

125964

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

125965

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.249

Low

125971

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.249

Low

125972

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

125974

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.249

Low

125915

DHX15
ATP-dependent RNA helicase DHX15

1

0

Small-scale

0.232

Low

125959

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.232

Low

125960

SYT2
Synaptotagmin-2

1

0

High-throughput

0.232

Low

125968

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low

125970

KLDC3
Kelch domain-containing protein 3

1

0

High-throughput

0.232

Low

125940

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.213

Low


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Last updated: 11Aug2025