Protein: MCM8
DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8)

Gene: MCM8
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q9UJA3

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0003682 - chromatin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1348004

MCM9
DNA helicase MCM9

8

19

Small-scale

0.967

High

708795

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.691

High

1312152

MCMBP
Mini-chromosome maintenance complex-binding protein

3

20

Small-scale

0.656

High

132044

VMA5A
von Willebrand factor A domain-containing protein 5A

2

1

High-throughput

0.628

High

428488

TBB5
Tubulin beta chain

2

13

High-throughput

0.628

High

1237391

TSYL6
Testis-specific Y-encoded-like protein 6

2

5

High-throughput

0.628

High

708540

MCM4
DNA replication licensing factor MCM4

1

19

Small-scale

0.618

High

709105

MCM7
DNA replication licensing factor MCM7

1

20

Small-scale

0.618

High

1055654

MCM6
DNA replication licensing factor MCM6

1

20

Small-scale

0.618

High

1058096

PSF1
DNA replication complex GINS protein PSF1

1

13

Small-scale

0.618

High

1355964

MCM8
DNA helicase MCM8

1

18

Small-scale

0.618

High

776423

MLH1
DNA mismatch repair protein Mlh1

2

5

Small-scale

0.611

High

794336

MSH2
DNA mismatch repair protein Msh2

2

4

Small-scale

0.611

High

1295634

FEM1C
Protein fem-1 homolog C

2

3

High-throughput

0.606

High

1031299

SKP2
S-phase kinase-associated protein 2

2

0

High-throughput

0.602

High

341297

FA9
Coagulation factor IX

2

1

High-throughput

0.574

High

1103175

KLH40
Kelch-like protein 40

2

11

High-throughput

0.574

High

1169033

DEFI8
Differentially expressed in FDCP 8 homolog

2

1

High-throughput

0.574

High

1319405

LRC27
Leucine-rich repeat-containing protein 27

2

1

High-throughput

0.574

High

1355965

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

4

High-throughput

0.574

High

1355966

KLK5
Kallikrein-5

2

1

High-throughput

0.558

High

535958

MIF
Macrophage migration inhibitory factor

1

4

High-throughput

0.536

High

569026

CAN2
Calpain-2 catalytic subunit

1

1

High-throughput

0.536

High

595465

LMNB1
Lamin-B1

1

12

High-throughput

0.536

High

602886

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

4

High-throughput

0.536

High

855577

MSH6
DNA mismatch repair protein Msh6

1

4

High-throughput

0.536

High

1069556

TEBP
Prostaglandin E synthase 3

1

5

High-throughput

0.536

High

1237070

HORM2
HORMA domain-containing protein 2

1

2

High-throughput

0.536

High

502664

BIP
Endoplasmic reticulum chaperone BiP

1

12

High-throughput

0.515

High

1232397

HROB
Homologous recombination OB-fold protein

1

1

Small-scale

0.515

High

180103

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

260678

AVIL
Advillin

1

2

High-throughput

0.489

High

486054

RAP2A
Ras-related protein Rap-2a

1

1

High-throughput

0.489

High

725604

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.489

High

163434

XPO1
Exportin-1

1

5

High-throughput

0.479

High

846892

SMCA2
Probable global transcription activator SNF2L2

1

8

High-throughput

0.479

High

1033450

ORC2
Origin recognition complex subunit 2

1

9

Small-scale

0.479

High

1035038

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

14

High-throughput

0.479

High

1203527

SKAP1
Src kinase-associated phosphoprotein 1

1

11

High-throughput

0.479

High

1223019

FANCM
Fanconi anemia group M protein

1

20

Small-scale

0.479

High

1272053

RAD50
DNA repair protein RAD50

1

20

Small-scale

0.479

High

1306121

CDC6
Cell division control protein 6 homolog

1

20

Small-scale

0.479

High

1354781

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1016450

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.458

High

1348590

DONS
Protein downstream neighbor of Son

1

5

Small-scale

0.445

High

1316801

ACE2
Angiotensin-converting enzyme 2

1

2

Small-scale

0.437

High

326357

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.279

Low

1231052

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

0

High-throughput

0.279

Low

1236199

IQCF1
IQ domain-containing protein F1

1

0

High-throughput

0.279

Low

1282312

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

1290952

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1296572

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

947180

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.269

Low

484907

GAGE1
G antigen 1

1

0

High-throughput

0.232

Low

1012578

YL016
Putative uncharacterized protein LOC100128554

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024