Protein: LYPA2
Acyl-protein thioesterase 2 (APT-2) (EC 3.1.2.-) (Lysophospholipase II) (LPL-II) (LysoPLA II) (Palmitoyl-protein hydrolase) (EC 3.1.2.22)

Gene: LYPA2, LYPLA2
Organism: Homo sapiens
Interactions: 47
UniProt ID: O95372

Gene Ontology (top 5):
GO:0002084 - protein depalmitoylation
GO:0004622 - phosphatidylcholine lysophospholipase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005795 - Golgi stack

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

334625

SGO2
Shugoshin 2

3

0

High-throughput

0.638

High

334640

OAZ3
Ornithine decarboxylase antizyme 3

2

0

High-throughput

0.602

High

334644

KIF3A
Kinesin-like protein KIF3A

2

0

High-throughput

0.602

High

334607

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.601

High

334633

LST8
Target of rapamycin complex subunit LST8

2

0

High-throughput

0.585

High

334620

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

334632

SCMH1
Polycomb protein SCMH1

1

1

High-throughput

0.541

High

334609

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

334615

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.536

High

257701

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.518

High

334643

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

334628

NPSR1
Neuropeptide S receptor

1

0

High-throughput

0.513

High

334624

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.493

High

334602

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

334604

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

334614

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.479

High

334617

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

334621

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

334623

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

334629

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

334636

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

334639

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

334645

TRI17
E3 ubiquitin-protein ligase TRIM17

1

1

Small-scale

0.479

High

131642

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

334601

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

334603

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

334605

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

334608

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

334610

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

334612

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

334613

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

334616

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

334618

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

334619

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.458

High

334631

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

334637

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

334638

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

334626

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

334606

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

334611

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.426

High

334634

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.426

High

334641

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

334635

NYX
Nyctalopin

3

0

High-throughput

0.347

High

334627

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

334630

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

334642

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

334622

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025