Protein: SGO2
Shugoshin 2 (Shugoshin-2) (Shugoshin-like 2) (Tripin)

Gene: SGO2
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q562F6

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007059 - chromosome segregation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

994247

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

4

1

Small-scale

0.694

High

1016913

H33
Histone H3.3

3

3

High-throughput

0.667

High

1200964

PKP3
Plakophilin-3

3

1

High-throughput

0.667

High

1029308

SET
Protein SET

4

0

Small-scale

0.660

High

1099693

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

1

Small-scale

0.653

High

718130

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

3

1

Small-scale

0.650

High

334625

LYPA2
Acyl-protein thioesterase 2

3

0

High-throughput

0.638

High

870486

PPCE
Prolyl endopeptidase

3

0

High-throughput

0.638

High

1098623

SBP1
Methanethiol oxidase

3

0

High-throughput

0.638

High

1200952

IER2
Immediate early response gene 2 protein

3

0

High-throughput

0.638

High

1200957

ARL8B
ADP-ribosylation factor-like protein 8B

3

0

High-throughput

0.638

High

1200963

PADI3
Protein-arginine deiminase type-3

3

0

High-throughput

0.638

High

717839

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

1

High-throughput

0.628

High

1200938

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

2

1

High-throughput

0.628

High

1143884

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

2

2

Small-scale

0.625

High

1117943

PKP1
Plakophilin-1

2

1

High-throughput

0.611

High

1200961

SPB13
Serpin B13

2

1

High-throughput

0.611

High

1200950

WDR83
WD repeat domain-containing protein 83

3

1

High-throughput

0.609

High

1131666

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

2

2

Small-scale

0.562

High

787656

SPB5
Serpin B5

2

1

High-throughput

0.558

High

1200937

H37
Histone H3-7

2

3

High-throughput

0.552

High

1200120

BOREA
Borealin

1

0

Small-scale

0.518

High

1162956

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.515

High

407634

S100B
Protein S100-B

1

0

High-throughput

0.513

High

625425

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

761701

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.513

High

872398

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

1200943

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1200951

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.513

High

1200955

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1200956

SPS2L
SPATS2-like protein

1

0

High-throughput

0.513

High

967778

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

Small-scale

0.484

High

1136735

MD2BP
MAD2L1-binding protein

1

0

Small-scale

0.479

High

449728

H2B1J
Histone H2B type 1-J

1

2

High-throughput

0.479

High

883561

CENPA
Histone H3-like centromeric protein A

1

3

High-throughput

0.479

High

980818

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

984144

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.479

High

998396

H31
Histone H3.1

1

3

High-throughput

0.479

High

1200947

EXOS8
Exosome complex component RRP43

1

0

High-throughput

0.460

High

1200959

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.460

High

190938

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

316879

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.458

High

487388

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

776966

PPM1A
Protein phosphatase 1A

1

0

Small-scale

0.458

High

799185

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

799920

COIL
Coilin

1

0

High-throughput

0.458

High

867183

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

867790

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.458

High

885800

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.458

High

1045362

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1106934

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1200934

SGO2
Shugoshin 2

1

0

Small-scale

0.458

High

1200940

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1200944

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1200945

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1200948

SPDLY
Protein Spindly

1

0

High-throughput

0.458

High

1200953

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1200954

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1200958

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.458

High

1023796

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.445

High

1158050

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

2

Small-scale

0.445

High

372209

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.426

High

1200936

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.426

High

1200949

KIF2C
Kinesin-like protein KIF2C

1

0

Small-scale

0.426

High

169254

CASQ2
Calsequestrin-2

3

0

High-throughput

0.347

High

326711

DUS14
Dual specificity protein phosphatase 14

3

0

High-throughput

0.347

High

1200939

HPHL1
Ferroxidase HEPHL1

3

0

High-throughput

0.347

High

1200941

LYG2
Lysozyme g-like protein 2

3

0

High-throughput

0.347

High

1200942

DSG4
Desmoglein-4

3

0

High-throughput

0.347

High

1200946

LRC15
Leucine-rich repeat-containing protein 15

3

0

High-throughput

0.347

High

1200935

CAHM4
Calcium homeostasis modulator protein 4

2

0

High-throughput

0.328

High

516667

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

0

High-throughput

0.288

High

390064

ALBU
Albumin

1

0

High-throughput

0.279

Low

1149488

RGN
Regucalcin

1

0

High-throughput

0.279

Low

296706

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.269

Low

993895

TYB10
Thymosin beta-10

1

0

High-throughput

0.249

Low

1050027

PLP2
Proteolipid protein 2

1

0

High-throughput

0.249

Low

1200960

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

1200962

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025