Protein: P2RX6
P2X purinoceptor 6 (P2X6) (ATP receptor) (P2XM) (Purinergic receptor) (Purinergic receptor P2X-like 1)

Gene: P2RX6
Organism: Homo sapiens
Interactions: 62
UniProt ID: O15547

Gene Ontology (top 5):
GO:0001614 - purinergic nucleotide receptor activity
GO:0004888 - transmembrane signaling receptor activity
GO:0004931 - extracellularly ATP-gated monoatomic cation channel activity
GO:0005524 - ATP binding
GO:0005637 - nuclear inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

194480

DNJB4
DnaJ homolog subfamily B member 4

4

1

High-throughput

0.691

High

194484

BAG5
BAG family molecular chaperone regulator 5

3

0

High-throughput

0.638

High

194428

DNJB5
DnaJ homolog subfamily B member 5

3

1

High-throughput

0.609

High

194427

PEPL
Periplakin

1

1

High-throughput

0.536

High

194430

THRB
Prothrombin

1

2

High-throughput

0.536

High

194432

PLMN
Plasminogen

1

1

High-throughput

0.536

High

194436

CO3
Complement C3

1

4

High-throughput

0.536

High

194444

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

2

High-throughput

0.536

High

194445

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

2

High-throughput

0.536

High

194446

FIBG
Fibrinogen gamma chain

1

2

High-throughput

0.536

High

194449

ALBU
Albumin

1

1

High-throughput

0.536

High

194450

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.536

High

194455

CO4A
Complement C4-A

1

4

High-throughput

0.536

High

194468

ITIH4
Inter-alpha-trypsin inhibitor heavy chain H4

1

1

High-throughput

0.536

High

194479

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.536

High

126213

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.513

High

194429

CERU
Ceruloplasmin

1

0

High-throughput

0.513

High

194442

CRYAB
Alpha-crystallin B chain

1

0

High-throughput

0.513

High

194443

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

194448

TTHY
Transthyretin

1

0

High-throughput

0.513

High

194451

TRFE
Serotransferrin

1

0

High-throughput

0.513

High

194454

INVO
Involucrin

1

0

High-throughput

0.513

High

194460

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.513

High

194461

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

High-throughput

0.513

High

194465

PKP1
Plakophilin-1

1

0

High-throughput

0.513

High

194471

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

194473

RDHE2
Epidermal retinol dehydrogenase 2

1

0

High-throughput

0.513

High

194478

ARL8B
ADP-ribosylation factor-like protein 8B

1

0

High-throughput

0.513

High

194482

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.513

High

194453

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

194426

KLK10
Kallikrein-10

1

1

High-throughput

0.489

High

194431

HPT
Haptoglobin

1

3

High-throughput

0.489

High

194433

A1AT
Alpha-1-antitrypsin

1

1

High-throughput

0.489

High

194434

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.489

High

194435

A2MG
Alpha-2-macroglobulin

1

4

High-throughput

0.489

High

194447

A1AG1
Alpha-1-acid glycoprotein 1

1

1

High-throughput

0.489

High

194457

A1AG2
Alpha-1-acid glycoprotein 2

1

1

High-throughput

0.489

High

194458

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

1

High-throughput

0.489

High

194463

HBB
Hemoglobin subunit beta

1

1

High-throughput

0.489

High

194464

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.489

High

194466

TRI29
Tripartite motif-containing protein 29

1

1

High-throughput

0.489

High

194475

EVPL
Envoplakin

1

1

High-throughput

0.489

High

194483

KLK9
Kallikrein-9

1

1

High-throughput

0.489

High

194467

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

194470

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

194481

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

194437

IGHG1
Immunoglobulin heavy constant gamma 1

1

4

High-throughput

0.445

High

194438

IGHG2
Immunoglobulin heavy constant gamma 2

1

4

High-throughput

0.445

High

194439

IGHG3
Immunoglobulin heavy constant gamma 3

1

5

High-throughput

0.445

High

194440

IGHG4
Immunoglobulin heavy constant gamma 4

1

4

High-throughput

0.445

High

194441

IGHM
Immunoglobulin heavy constant mu

1

4

High-throughput

0.445

High

194477

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.445

High

75633

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

4

High-throughput

0.437

High

194472

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.426

High

194476

SRPK1
SRSF protein kinase 1

1

0

High-throughput

0.426

High

69453

A2ML1
Alpha-2-macroglobulin-like protein 1

1

4

High-throughput

0.407

High

194452

HEMO
Hemopexin

1

0

High-throughput

0.279

Low

194456

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.279

Low

194459

FILA
Filaggrin

1

0

High-throughput

0.279

Low

194462

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

194469

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

194474

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025