Protein: SKA1
SKA complex subunit 1 (Spindle and kinetochore-associated protein 1)

Gene: SKA1
Organism: Homo sapiens
Interactions: 71
UniProt ID: Q96BD8

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1358236

SKA2
Spindle and kinetochore-associated protein 2

6

0

Small-scale

0.908

High

1311952

SKA3
Spindle and kinetochore-associated protein 3

10

0

Small-scale

0.723

High

969018

PRS8
26S proteasome regulatory subunit 8

5

1

High-throughput

0.721

High

1384519

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

6

0

High-throughput

0.707

High

1023852

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

4

1

High-throughput

0.701

High

1384520

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

4

1

High-throughput

0.691

High

343438

SNP29
Synaptosomal-associated protein 29

4

0

High-throughput

0.670

High

1384504

P5CR2
Pyrroline-5-carboxylate reductase 2

3

0

High-throughput

0.638

High

1339646

TNIP2
TNFAIP3-interacting protein 2

2

0

High-throughput

0.585

High

333385

SNAPN
SNARE-associated protein Snapin

2

0

High-throughput

0.580

High

391393

FRIL
Ferritin light chain

2

0

High-throughput

0.576

High

1123749

DCTN1
Dynactin subunit 1

2

0

High-throughput

0.559

High

1322125

SYCE1
Synaptonemal complex central element protein 1

1

0

High-throughput

0.549

High

1143461

PCM1
Pericentriolar material 1 protein

2

0

High-throughput

0.547

High

968779

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.536

High

122829

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.513

High

133680

WASL
Actin nucleation-promoting factor WASL

1

0

High-throughput

0.513

High

251374

GMDS
GDP-mannose 4,6 dehydratase

1

0

High-throughput

0.513

High

287991

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.513

High

347232

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

445231

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

1243030

PKN3
Serine/threonine-protein kinase N3

1

0

High-throughput

0.513

High

1279848

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

1

0

High-throughput

0.513

High

1323823

INT1
Integrator complex subunit 1

1

0

High-throughput

0.513

High

1331955

ASCC1
Activating signal cointegrator 1 complex subunit 1

1

0

High-throughput

0.513

High

1384506

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.513

High

1384515

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

1384518

NUDT5
ADP-sugar pyrophosphatase

1

0

High-throughput

0.513

High

1384507

AURKB
Aurora kinase B

1

0

Small-scale

0.480

High

1197049

AMOT
Angiomotin

1

1

High-throughput

0.479

High

1350682

CCHCR
Coiled-coil alpha-helical rod protein 1

1

1

High-throughput

0.479

High

164040

NDC80
Kinetochore protein NDC80 homolog

1

0

Small-scale

0.460

High

1334211

SPC24
Kinetochore protein Spc24

1

0

Small-scale

0.460

High

613426

VINC
Vinculin

1

0

High-throughput

0.458

High

831203

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

970891

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1156176

ZYX
Zyxin

1

0

High-throughput

0.458

High

1177985

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1210941

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.458

High

1322418

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

1371049

ARHG2
Rho guanine nucleotide exchange factor 2

1

0

Small-scale

0.458

High

1384508

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1384513

MIS12
Protein MIS12 homolog

1

0

Small-scale

0.458

High

1384514

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1384516

TRI36
E3 ubiquitin-protein ligase TRIM36

1

0

High-throughput

0.458

High

1384517

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

59229

A2ABH1
Coiled-coil alpha-helical rod protein 1

1

1

High-throughput

0.445

High

1382713

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.437

High

81649

B5MDE0
Protein RFT1 homolog

1

1

High-throughput

0.407

High

1384509

NP1L5
Nucleosome assembly protein 1-like 5

4

0

High-throughput

0.360

High

1316915

FAM9C
Protein FAM9C

3

0

High-throughput

0.346

High

51367

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

2

0

High-throughput

0.316

High

50651

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.279

Low

176362

SYNEM
Synemin

1

0

High-throughput

0.279

Low

339561

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.279

Low

1037026

DSC2
Desmocollin-2

1

0

High-throughput

0.279

Low

1179832

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1210732

ZMYM1
Zinc finger MYM-type protein 1

1

0

High-throughput

0.279

Low

1256785

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

0

High-throughput

0.279

Low

1384505

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.279

Low

1384510

LENG8
Leukocyte receptor cluster member 8

1

0

High-throughput

0.279

Low

1384511

BTBD9
BTB/POZ domain-containing protein 9

1

0

High-throughput

0.279

Low

1384512

BEGIN
Brain-enriched guanylate kinase-associated protein

1

0

High-throughput

0.279

Low

4793

A0A1B0GWI1
Coiled-coil domain containing 196

1

0

High-throughput

0.268

Low

1276608

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

262416

DTNB
Dystrobrevin beta

1

0

High-throughput

0.238

Low

1336085

CC197
Uncharacterized protein CCDC197

1

0

High-throughput

0.238

Low

58894

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

87519

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

379439

IGHG3
Immunoglobulin heavy constant gamma 3

1

0

High-throughput

0.232

Low

1211945

S35F1
Solute carrier family 35 member F1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025