Protein: PKH4B
Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B)

Gene: PKH4B, PLEKHG4B
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q96PX9

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

177402

ARHGB
Rho guanine nucleotide exchange factor 11

2

19

High-throughput

0.767

High

1400318

ARHGC
Rho guanine nucleotide exchange factor 12

2

19

High-throughput

0.767

High

1353098

ARH40
Rho guanine nucleotide exchange factor 40

2

14

High-throughput

0.737

High

955490

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.692

High

1400319

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

3

High-throughput

0.618

High

1125917

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

2

High-throughput

0.575

High

214001

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

3

High-throughput

0.571

High

370351

CYTA
Cystatin-A

2

1

High-throughput

0.571

High

1314681

SRRM1
Serine/arginine repetitive matrix protein 1

2

5

High-throughput

0.571

High

1324912

RHG18
Rho GTPase-activating protein 18

2

4

High-throughput

0.571

High

300211

GLRX3
Glutaredoxin-3

1

1

High-throughput

0.560

High

1116568

FHL3
Four and a half LIM domains protein 3

1

11

High-throughput

0.560

High

1400317

LYAR
Cell growth-regulating nucleolar protein

2

0

High-throughput

0.547

High

1400321

PSF2
DNA replication complex GINS protein PSF2

2

0

High-throughput

0.547

High

1391408

DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like

2

1

High-throughput

0.521

High

445050

S10A9
Protein S100-A9

1

5

High-throughput

0.479

High

699831

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

4

High-throughput

0.479

High

724795

METK2
S-adenosylmethionine synthase isoform type-2

1

1

High-throughput

0.479

High

973799

RUXE
Small nuclear ribonucleoprotein E

1

1

High-throughput

0.479

High

1036787

DSG1
Desmoglein-1

1

4

High-throughput

0.479

High

1114059

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1156186

ZYX
Zyxin

1

10

High-throughput

0.479

High

1400320

ATIF1
ATPase inhibitor, mitochondrial

1

1

High-throughput

0.479

High

1400323

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

6

High-throughput

0.479

High

290686

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.437

High

142607

IMA3
Importin subunit alpha-3

1

1

High-throughput

0.408

High

1400322

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025