HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 33961781, 23752268
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding
Common GO terms GO:0000118 - histone deacetylase complex
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 428
Hs

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Last updated: 15 Jul 2024