Interactor 1: ARHGB (O15085)
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)
Gene: ARHGEF11
Interactor 2: PKH4B (Q96PX9)
Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B)
Gene: PLEKHG4B
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 1.00 | 0.767 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, unassigned2213 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH_16~RhoGEF, RhoGEF~RhoGEF, RhoGEF~SOS1_NGEF_PH |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0051056 - regulation of small GTPase mediated signal transduction |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
