Interactor 1: FA10 (P00742)
Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]
Gene: F10
Interactor 2: ZPI (Q9UK55)
Protein Z-dependent protease inhibitor (PZ-dependent protease inhibitor) (PZI) (Serpin A10)
Gene: SERPINA10
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.692 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20427285 |
| Identification Methods | affinity technology, comigration in non denaturing gel electrophoresis |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FXa_inhibition~Serpin, Serpin~Trypsin |
| Common GO terms | GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen GO:0007596 - blood coagulation |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
