Protein: VGF
Neurosecretory protein VGF [Cleaved into: Neuroendocrine regulatory peptide-1 (NERP-1); Neuroendocrine regulatory peptide-2 (NERP-2); VGF-derived peptide TLQP-21; VGF-derived peptide TLQP-62; Antimicrobial peptide VGF[554-577]]

Gene: VGF
Organism: Homo sapiens
Interactions: 44
UniProt ID: O15240

Gene Ontology (top 5):
GO:0001541 - ovarian follicle development
GO:0002021 - response to dietary excess
GO:0005179 - hormone activity
GO:0005184 - neuropeptide hormone activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

183835

ANF
Natriuretic peptides A

2

0

High-throughput

0.576

High

183850

PPT1
Palmitoyl-protein thioesterase 1

2

0

Small-scale

0.559

High

183837

VIP
VIP peptides [Cleaved into: Intestinal peptide PHV-42

1

2

High-throughput

0.536

High

183838

IFN10
Interferon alpha-10

1

2

High-throughput

0.536

High

183860

IFNE
Interferon epsilon

1

2

High-throughput

0.536

High

183868

IL20
Interleukin-20

1

1

High-throughput

0.536

High

183841

IFNA6
Interferon alpha-6

1

2

High-throughput

0.515

High

183836

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

0

High-throughput

0.513

High

183839

CRP

1

0

High-throughput

0.513

High

183848

IL10
Interleukin-10

1

0

High-throughput

0.513

High

183851

NOGG
Noggin

1

0

High-throughput

0.513

High

183853

EP3A
Epididymal secretory protein E3-alpha

1

0

High-throughput

0.513

High

183869

DKK3
Dickkopf-related protein 3

1

0

High-throughput

0.513

High

183871

ALK
ALK tyrosine kinase receptor

1

1

High-throughput

0.489

High

183830

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

183862

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

183846

PACA
Pituitary adenylate cyclase-activating polypeptide

1

1

High-throughput

0.445

High

183856

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

183870

DKKL1
Dickkopf-like protein 1

1

1

High-throughput

0.445

High

183840

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

183842

MMP3
Stromelysin-1

1

0

High-throughput

0.426

High

183843

SPRC
SPARC

1

0

High-throughput

0.426

High

183844

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

183849

CEAM8
Cell adhesion molecule CEACAM8

1

0

High-throughput

0.426

High

183858

RABEK
Rab9 effector protein with kelch motifs

1

0

High-throughput

0.426

High

183861

TSC1
Hamartin

1

0

Small-scale

0.426

High

183865

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

0

High-throughput

0.426

High

183855

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

1

High-throughput

0.407

High

183866

CD244
Natural killer cell receptor 2B4

1

1

High-throughput

0.407

High

183833

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

0

High-throughput

0.279

Low

183834

NXPH2
Neurexophilin-2

1

0

High-throughput

0.279

Low

183847

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.279

Low

183852

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.279

Low

183864

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.279

Low

183867

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

High-throughput

0.279

Low

183873

PRG3
Proteoglycan 3

1

0

High-throughput

0.279

Low

183854

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.269

Low

183857

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

183863

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.249

Low

183831

CST8
Cystatin-8

1

0

High-throughput

0.232

Low

183832

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

183845

PPA5
Tartrate-resistant acid phosphatase type 5

1

0

High-throughput

0.232

Low

183859

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.232

Low

183872

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025