Protein: SPXN4
Sperm protein associated with the nucleus on the X chromosome N4 (Nuclear-associated protein SPAN-Xn4) (SPANX-N4) (SPANX family member N4)

Gene: SPXN4, SPANXN4
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q5MJ08

Gene Ontology (top 5):

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

320825

KLH18
Kelch-like protein 18

1

1

High-throughput

0.489

High

412960

CPNS1
Calpain small subunit 1

1

1

High-throughput

0.489

High

606005

CAN2
Calpain-2 catalytic subunit

1

1

High-throughput

0.489

High

619067

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

High-throughput

0.489

High

691768

MK03
Mitogen-activated protein kinase 3

1

2

High-throughput

0.489

High

703615

MK01
Mitogen-activated protein kinase 1

1

3

High-throughput

0.489

High

853698

MK08
Mitogen-activated protein kinase 8

1

5

High-throughput

0.489

High

853806

MK09
Mitogen-activated protein kinase 9

1

5

High-throughput

0.489

High

923356

MK12
Mitogen-activated protein kinase 12

1

5

High-throughput

0.489

High

1066336

RBBP4
Histone-binding protein RBBP4

1

1

High-throughput

0.489

High

1158110

MK14
Mitogen-activated protein kinase 14

1

5

High-throughput

0.489

High

1158867

RBBP7
Histone-binding protein RBBP7

1

1

High-throughput

0.489

High

1208221

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

1

High-throughput

0.489

High

1208237

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

2

High-throughput

0.489

High

1208218

CSAG1
Chondrosarcoma-associated gene 1 protein

1

1

High-throughput

0.407

High

1208250

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

1

High-throughput

0.407

High

1208233

SRPK1
SRSF protein kinase 1

1

0

High-throughput

0.287

High

48361

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

0

High-throughput

0.279

Low

215309

TXNL1
Thioredoxin-like protein 1

1

0

High-throughput

0.279

Low

835687

KPCI
Protein kinase C iota type

1

0

High-throughput

0.279

Low

878261

DPOD2
DNA polymerase delta subunit 2

1

0

High-throughput

0.279

Low

881778

DHYS
Deoxyhypusine synthase

1

0

High-throughput

0.279

Low

902930

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.279

Low

1097206

PAK2
Serine/threonine-protein kinase PAK 2

1

0

High-throughput

0.279

Low

1102712

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

0

High-throughput

0.279

Low

1111915

SNX1
Sorting nexin-1

1

0

High-throughput

0.279

Low

1130900

PSF1
DNA replication complex GINS protein PSF1

1

0

High-throughput

0.279

Low

1149900

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.279

Low

1208219

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.279

Low

1208220

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.279

Low

1208222

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.279

Low

1208223

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.279

Low

1208224

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.279

Low

1208225

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.279

Low

1208226

FAD1
FAD synthase

1

0

High-throughput

0.279

Low

1208227

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

0

High-throughput

0.279

Low

1208228

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.279

Low

1208229

F120B
Constitutive coactivator of peroxisome proliferator-activated receptor gamma

1

0

High-throughput

0.279

Low

1208230

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.279

Low

1208231

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.279

Low

1208232

SNX27
Sorting nexin-27

1

0

High-throughput

0.279

Low

1208234

AEDO
2-aminoethanethiol dioxygenase

1

0

High-throughput

0.279

Low

1208235

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.279

Low

1208236

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

High-throughput

0.279

Low

1208238

HDHD2
Haloacid dehalogenase-like hydrolase domain-containing protein 2

1

0

High-throughput

0.279

Low

1208239

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

1

0

High-throughput

0.279

Low

1208240

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

High-throughput

0.279

Low

1208241

LANC2
LanC-like protein 2

1

0

High-throughput

0.279

Low

1208242

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.279

Low

1208243

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.279

Low

1208244

INT9
Integrator complex subunit 9

1

0

High-throughput

0.279

Low

1208245

PNPO
Pyridoxine-5'-phosphate oxidase

1

0

High-throughput

0.279

Low

1208246

DCA16
DDB1- and CUL4-associated factor 16

1

0

High-throughput

0.279

Low

1208247

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.279

Low

1208248

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

High-throughput

0.279

Low

1208249

ASB3
Ankyrin repeat and SOCS box protein 3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025