Protein: SUGP2
SURP and G-patch domain-containing protein 2 (Arginine/serine-rich-splicing factor 14) (Splicing factor, arginine/serine-rich 14)

Gene: SUGP2
Organism: Homo sapiens
Interactions: 154
UniProt ID: Q8IX01

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
GO:0008380 - RNA splicing
GO:0016604 - nuclear body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1311613

DDX21
Nucleolar RNA helicase 2

1

8

High-throughput

0.691

High

485252

ROA1
Heterogeneous nuclear ribonucleoprotein A1

3

5

Small-scale

0.656

High

846374

MATR3
Matrin-3

3

5

High-throughput

0.656

High

372514

MYC
Myc proto-oncogene protein

3

9

High-throughput

0.640

High

1090255

ELAV2
ELAV-like protein 2

2

7

High-throughput

0.628

High

1311605

NXF2
Nuclear RNA export factor 2

2

3

High-throughput

0.628

High

1088435

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

6

High-throughput

0.618

High

1132813

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

6

High-throughput

0.618

High

344240

PTBP3
Polypyrimidine tract-binding protein 3

2

3

High-throughput

0.601

High

462504

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

10

High-throughput

0.601

High

1311611

LN28A
Protein lin-28 homolog A

2

2

High-throughput

0.601

High

1100099

TIF1B
Transcription intermediary factor 1-beta

2

1

Small-scale

0.584

High

1311618

ZRAN1
Ubiquitin thioesterase ZRANB1

2

6

High-throughput

0.584

High

1009245

PRR3
Proline-rich protein 3

2

0

High-throughput

0.576

High

1311620

DDX41
Probable ATP-dependent RNA helicase DDX41

1

6

High-throughput

0.575

High

951742

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

0

Small-scale

0.569

High

1063411

GOGA2
Golgin subfamily A member 2

2

4

High-throughput

0.553

High

48023

RBM47
RNA-binding protein 47

1

1

High-throughput

0.536

High

158250

COPE
Coatomer subunit epsilon

1

1

High-throughput

0.536

High

166168

AIM2
Interferon-inducible protein AIM2

1

2

High-throughput

0.536

High

338893

CBX6
Chromobox protein homolog 6

1

1

High-throughput

0.536

High

872507

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.536

High

1065288

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

1089468

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.536

High

1115796

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.536

High

1148721

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

8

High-throughput

0.536

High

1159995

SRSF7
Serine/arginine-rich splicing factor 7

1

6

High-throughput

0.536

High

1160199

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

2

High-throughput

0.536

High

1250612

BCOR
BCL-6 corepressor

1

2

Small-scale

0.536

High

1311585

LAR4B
La-related protein 4B

1

1

High-throughput

0.536

High

1311599

RBM4B
RNA-binding protein 4B

1

10

High-throughput

0.536

High

428848

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

879735

MAPK2
MAP kinase-activated protein kinase 2

1

0

High-throughput

0.513

High

1311578

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

0

High-throughput

0.513

High

1311606

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

0

High-throughput

0.513

High

1311609

SENP3
Sentrin-specific protease 3

1

0

High-throughput

0.513

High

1311619

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

1311621

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

927402

ATX1
Ataxin-1

1

3

High-throughput

0.508

High

1311601

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

5

High-throughput

0.500

High

424431

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.493

High

773555

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.489

High

848672

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

1116527

FHL3
Four and a half LIM domains protein 3

1

3

High-throughput

0.489

High

1124489

MAP7
Ensconsin

1

2

High-throughput

0.489

High

505585

ATX1L
Ataxin-1-like

1

3

High-throughput

0.481

High

129240

MEN1
Menin

1

2

High-throughput

0.479

High

170223

AURKA
Aurora kinase A

1

3

High-throughput

0.479

High

260156

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

331125

KI20A
Kinesin-like protein KIF20A

1

7

High-throughput

0.479

High

346043

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

406365

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.479

High

520191

ANDR
Androgen receptor

1

12

High-throughput

0.479

High

558257

XRCC6
X-ray repair cross-complementing protein 6

1

2

High-throughput

0.479

High

589105

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

590449

GATA1
Erythroid transcription factor

1

2

High-throughput

0.479

High

657627

GCSP
Glycine dehydrogenase

1

3

High-throughput

0.479

High

662605

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

2

High-throughput

0.479

High

664774

CCND1
G1/S-specific cyclin-D1

1

1

High-throughput

0.479

High

695889

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

731445

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

765687

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.479

High

768599

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

848106

NR4A2
Nuclear receptor subfamily 4 group A member 2

1

9

High-throughput

0.479

High

851607

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

881561

CDK8
Cyclin-dependent kinase 8

1

3

High-throughput

0.479

High

897333

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

904909

MECP2
Methyl-CpG-binding protein 2

1

5

High-throughput

0.479

High

945713

FOXL2
Forkhead box protein L2

1

2

High-throughput

0.479

High

986549

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

1008794

RED1
Double-stranded RNA-specific editase 1

1

4

High-throughput

0.479

High

1024687

VIGLN
Vigilin

1

5

High-throughput

0.479

High

1035759

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

1096746

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.479

High

1100879

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

1126989

RBM39
RNA-binding protein 39

1

8

High-throughput

0.479

High

1215700

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1235464

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

1286991

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.479

High

1289234

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.479

High

1289444

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1290576

ZCH18
Zinc finger CCCH domain-containing protein 18

1

5

High-throughput

0.479

High

1311576

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1311577

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

1311586

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

1311587

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

1311588

FUBP1
Far upstream element-binding protein 1

1

4

High-throughput

0.479

High

1311590

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.479

High

1311592

AURKB
Aurora kinase B

1

3

High-throughput

0.479

High

1311596

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.479

High

1311602

FOXP3
Forkhead box protein P3

1

4

High-throughput

0.479

High

1311604

WWTR1
WW domain-containing transcription regulator protein 1

1

4

High-throughput

0.479

High

1311607

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1311612

RC3H2
Roquin-2

1

7

High-throughput

0.479

High

1311614

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

1311616

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1311589

EXOS8
Exosome complex component RRP43

1

0

High-throughput

0.460

High

447199

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

1311583

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1311617

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1311625

RUVB2
RuvB-like 2

1

0

High-throughput

0.458

High

1198592

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

1288893

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.445

High

1311594

CEP63
Centrosomal protein of 63 kDa

1

4

High-throughput

0.445

High

157588

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.437

High

242215

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.437

High

272308

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.437

High

363536

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.437

High

401114

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.437

High

886294

ARL4D
ADP-ribosylation factor-like protein 4D

1

4

High-throughput

0.437

High

970748

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1091313

FOXL1
Forkhead box protein L1

1

2

High-throughput

0.437

High

1140526

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.437

High

1228991

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.437

High

1233913

Q6ICH2
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.437

High

1254546

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1276458

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1311579

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

1311582

HIPK4
Homeodomain-interacting protein kinase 4

1

2

High-throughput

0.437

High

1311597

FOXB1
Forkhead box protein B1

1

3

High-throughput

0.437

High

1311603

FOXQ1
Forkhead box protein Q1

1

3

High-throughput

0.437

High

1311610

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

1311615

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

Small-scale

0.437

High

1311622

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.437

High

1311623

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

1119195

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1311624

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.426

High

887010

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.408

High

73421

B2CML4
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.407

High

1253144

NBEL2
Neurobeachin-like protein 2

1

2

High-throughput

0.407

High

1311584

R3GEF
Guanine nucleotide exchange factor for Rab-3A

3

0

High-throughput

0.347

High

1311626

CLC11
C-type lectin domain family 11 member A

3

0

High-throughput

0.347

High

1311580

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

0

High-throughput

0.282

High

1127423

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1289418

FA83A
Protein FAM83A

1

0

High-throughput

0.279

Low

1311575

IQCF2
IQ domain-containing protein F2

1

0

High-throughput

0.279

Low

1311581

SAMD3
Sterile alpha motif domain-containing protein 3

1

0

High-throughput

0.279

Low

1311591

PABP5
Polyadenylate-binding protein 5

1

0

High-throughput

0.279

Low

1311593

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

1311595

PSKH2
Serine/threonine-protein kinase H2

1

0

High-throughput

0.279

Low

1311608

N62CL
Nucleoporin-62 C-terminal-like protein

1

0

High-throughput

0.279

Low

635462

CO5A1

1

0

High-throughput

0.269

Low

902856

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.269

Low

891235

GSK3A
Glycogen synthase kinase-3 alpha

1

0

High-throughput

0.265

Low

1023826

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.253

Low

655858

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.249

Low

791516

SYUA
Alpha-synuclein

1

0

High-throughput

0.249

Low

1246874

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1258056

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

1311598

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.249

Low

1311600

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.249

Low

877691

SL9A3
Sodium/hydrogen exchanger 3

1

0

High-throughput

0.232

Low

906314

GPC3
Glypican-3

1

0

High-throughput

0.232

Low

1311627

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025