Protein: DC4L2
DDB1- and CUL4-associated factor 4-like protein 2 (WD repeat-containing protein 21C)

Gene: DC4L2, DCAF4L2
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q8NA75

Gene Ontology (top 5):
GO:0080008 - Cul4-RING E3 ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114943

CUL4A
Cullin-4A

4

5

Small-scale

0.694

High

1115303

CUL4B
Cullin-4B

4

5

Small-scale

0.694

High

273080

CLU
Clustered mitochondria protein homolog

4

2

Small-scale

0.633

High

1157818

DDB1
DNA damage-binding protein 1

2

3

Small-scale

0.611

High

1332548

TCPW
T-complex protein 1 subunit zeta-2

2

13

High-throughput

0.558

High

958672

CSN2
COP9 signalosome complex subunit 2

2

5

Small-scale

0.533

High

610773

TCPA
T-complex protein 1 subunit alpha

1

8

High-throughput

0.489

High

786176

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.489

High

821452

TCPZ
T-complex protein 1 subunit zeta

1

10

High-throughput

0.489

High

1007144

TCPB
T-complex protein 1 subunit beta

1

11

High-throughput

0.489

High

1332553

PDRG1
p53 and DNA damage-regulated protein 1

1

1

High-throughput

0.489

High

1226470

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.479

High

532778

CH60
60 kDa heat shock protein, mitochondrial

1

4

Small-scale

0.437

High

535297

BIP
Endoplasmic reticulum chaperone BiP

1

1

Small-scale

0.437

High

550361

PABP1
Polyadenylate-binding protein 1

1

1

Small-scale

0.437

High

595821

H13
Histone H1.3

1

3

Small-scale

0.437

High

596239

H12
Histone H1.2

1

3

Small-scale

0.437

High

620479

NUCL
Nucleolin

1

1

Small-scale

0.437

High

623446

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

Small-scale

0.437

High

650858

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

Small-scale

0.437

High

899134

TCPQ
T-complex protein 1 subunit theta

1

13

Small-scale

0.437

High

965782

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

3

Small-scale

0.437

High

994664

YBOX1
Y-box-binding protein 1

1

4

Small-scale

0.437

High

1094373

CSN1
COP9 signalosome complex subunit 1

1

3

Small-scale

0.437

High

1272488

CSN6
COP9 signalosome complex subunit 6

1

3

Small-scale

0.437

High

1332549

CSN5
COP9 signalosome complex subunit 5

1

3

Small-scale

0.437

High

1332550

CSN8
COP9 signalosome complex subunit 8

1

1

Small-scale

0.437

High

1332551

CSN4
COP9 signalosome complex subunit 4

1

1

Small-scale

0.437

High

1332552

CSN7B
COP9 signalosome complex subunit 7b

1

2

Small-scale

0.437

High

1332554

CSN3
COP9 signalosome complex subunit 3

1

5

Small-scale

0.437

High

1332555

NUDC
Nuclear migration protein nudC

1

2

High-throughput

0.437

High

446169

PYGL
Glycogen phosphorylase, liver form

3

0

High-throughput

0.347

High

1230784

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.279

Low

162631

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.249

Low

290958

PPM1B
Protein phosphatase 1B

1

0

Small-scale

0.249

Low

456798

ANXA2
Annexin A2

1

0

Small-scale

0.249

Low

479847

GSTP1
Glutathione S-transferase P

1

0

Small-scale

0.249

Low

537527

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.249

Low

660117

COF1
Cofilin-1

1

0

Small-scale

0.249

Low

952606

MYL6
Myosin light polypeptide 6

1

0

Small-scale

0.249

Low

1057212

PRDX1
Peroxiredoxin-1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025