Protein: P4HTM
Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4)

Gene: P4HTM
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q9NXG6

Gene Ontology (top 5):
GO:0004656 - procollagen-proline 4-dioxygenase activity
GO:0005506 - iron ion binding
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1094297

PDIA2
Protein disulfide-isomerase A2

1

11

Small-scale

0.647

High

168459

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.578

High

1279383

DHB13
17-beta-hydroxysteroid dehydrogenase 13

1

2

High-throughput

0.536

High

1452019

DNJB9
DnaJ homolog subfamily B member 9

1

3

High-throughput

0.536

High

186948

GPR37
Prosaposin receptor GPR37

1

0

High-throughput

0.518

High

548130

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

1439362

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

846104

GLP1R
Glucagon-like peptide 1 receptor

1

1

Small-scale

0.504

High

508726

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

567996

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.489

High

1030223

IL5RA
Interleukin-5 receptor subunit alpha

1

1

High-throughput

0.489

High

1382074

T106A
Transmembrane protein 106A

1

3

High-throughput

0.489

High

1449623

CBLN4
Cerebellin-4

1

8

High-throughput

0.489

High

586206

CD1D
Antigen-presenting glycoprotein CD1d

1

1

Small-scale

0.479

High

1271021

RHOU
Rho-related GTP-binding protein RhoU

1

2

High-throughput

0.457

High

218854

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

1005169

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1255820

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1449972

T106B
Transmembrane protein 106B

1

3

High-throughput

0.437

High

936134

PAR2
Proteinase-activated receptor 2

1

0

High-throughput

0.282

High

1395298

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

1446176

LT4R2
Leukotriene B4 receptor 2

1

0

High-throughput

0.282

High

268941

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

0

High-throughput

0.279

Low

348773

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.279

Low

426142

PPB1
Alkaline phosphatase, placental type

1

0

High-throughput

0.279

Low

506910

CFC1
Cryptic protein

1

0

High-throughput

0.279

Low

607424

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

0

High-throughput

0.279

Low

946265

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

0

High-throughput

0.279

Low

1194717

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1366274

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.279

Low

1369072

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low

1411482

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

1452020

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

0

High-throughput

0.279

Low

1452022

LIPG
Endothelial lipase

1

0

High-throughput

0.279

Low

1139855

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

Small-scale

0.249

Low

947064

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

844884

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.232

Low

1314007

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1402854

DIRC2
Solute carrier family 49 member 4

1

0

High-throughput

0.232

Low

1452021

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025