Protein: DIRC2
Solute carrier family 49 member 4 (Disrupted in renal cancer protein 2) (Disrupted in renal carcinoma protein 2)

Gene: DIRC2, SLC49A4
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q96SL1

Gene Ontology (top 5):
GO:0005765 - lysosomal membrane
GO:0016020 - membrane
GO:0022857 - transmembrane transporter activity
GO:0031923 - pyridoxine transport
GO:0043231 - intracellular membrane-bounded organelle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1402849

S22A4
Solute carrier family 22 member 4

1

3

High-throughput

0.618

High

1391486

BSCL2
Seipin

2

1

High-throughput

0.549

High

132646

UPK1A
Uroplakin-1a

1

1

High-throughput

0.536

High

178369

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

256500

TOM1
Target of Myb1 membrane trafficking protein

1

1

High-throughput

0.445

High

273576

DJC13
DnaJ homolog subfamily C member 13

1

1

High-throughput

0.445

High

290261

TM1L1
TOM1-like protein 1

1

1

High-throughput

0.445

High

775775

ATP7B
Copper-transporting ATPase 2

1

1

High-throughput

0.445

High

1085367

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

1

High-throughput

0.445

High

1316739

AGRG2
Adhesion G-protein coupled receptor G2

1

1

High-throughput

0.445

High

1384756

ARL8A
ADP-ribosylation factor-like protein 8A

1

1

High-throughput

0.445

High

1402851

AT132
Polyamine-transporting ATPase 13A2

1

1

High-throughput

0.445

High

126173

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.426

High

140413

SDCB1
Syntenin-1

1

0

High-throughput

0.426

High

318211

DDHD2
Triacylglycerol hydrolase DDHD2

1

0

High-throughput

0.426

High

331915

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.426

High

477457

CD63
CD63 antigen

1

0

High-throughput

0.426

High

904084

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

1139028

SNX17
Sorting nexin-17

1

0

High-throughput

0.426

High

1211195

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.426

High

1248437

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

0

High-throughput

0.426

High

1257756

VP13C
Intermembrane lipid transfer protein VPS13C

1

0

High-throughput

0.426

High

1275398

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.426

High

1356979

PDC6I
Programmed cell death 6-interacting protein

1

0

High-throughput

0.426

High

1364924

AP3S1
AP-3 complex subunit sigma-1

1

0

High-throughput

0.426

High

1402845

ABCA3
Phospholipid-transporting ATPase ABCA3

1

0

High-throughput

0.426

High

1402853

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

0

High-throughput

0.426

High

1402855

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

High-throughput

0.426

High

1402856

UST
Uronyl 2-sulfotransferase

1

0

High-throughput

0.426

High

1228810

ANKS6
Ankyrin repeat and SAM domain-containing protein 6

1

1

High-throughput

0.407

High

861738

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.232

Low

1017535

RHG08
Rho GTPase-activating protein 8

1

0

High-throughput

0.232

Low

1085105

KIF1A
Kinesin-like protein KIF1A

1

0

High-throughput

0.232

Low

1235418

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.232

Low

1256353

AN13D
Ankyrin repeat domain-containing protein 13D

1

0

High-throughput

0.232

Low

1327882

MINY1
Ubiquitin carboxyl-terminal hydrolase MINDY-1

1

0

High-throughput

0.232

Low

1358344

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.232

Low

1402846

TM109
Voltage-gated monoatomic cation channel TMEM109

1

0

High-throughput

0.232

Low

1402847

T106C
Transmembrane protein 106C

1

0

High-throughput

0.232

Low

1402848

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.232

Low

1402850

TOLIP
Toll-interacting protein

1

0

High-throughput

0.232

Low

1402852

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.232

Low

1402854

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.232

Low

1402857

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025