Protein: SEM4F
Semaphorin-4F (Semaphorin-M) (Sema M) (Semaphorin-W) (Sema W)

Gene: SEM4F, SEMA4F
Organism: Homo sapiens
Interactions: 39
UniProt ID: O95754

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0007267 - cell-cell signaling
GO:0007399 - nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343865

ITM2B
Integral membrane protein 2B

3

1

High-throughput

0.667

High

343836

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

2

3

High-throughput

0.628

High

343852

CC50B
Cell cycle control protein 50B

2

2

High-throughput

0.628

High

343855

TM11B
Transmembrane protease serine 11B

2

4

High-throughput

0.628

High

343860

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

1

High-throughput

0.628

High

343830

SG1D1
Secretoglobin family 1D member 1

1

2

High-throughput

0.618

High

255728

USO1
General vesicular transport factor p115

2

1

High-throughput

0.612

High

343856

TMM25
Transmembrane protein 25

2

2

High-throughput

0.611

High

343840

GRIA3
Glutamate receptor 3

2

0

High-throughput

0.602

High

343831

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

12

High-throughput

0.536

High

343833

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

7

High-throughput

0.536

High

343837

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

11

High-throughput

0.536

High

343838

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

2

High-throughput

0.536

High

343841

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.536

High

343859

T106A
Transmembrane protein 106A

1

4

High-throughput

0.536

High

343862

CRLF2
Cytokine receptor-like factor 2

1

4

High-throughput

0.536

High

343864

CLC2D
C-type lectin domain family 2 member D

1

12

High-throughput

0.536

High

343847

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.506

High

343834

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.493

High

343842

ARSL
Arylsulfatase L

1

1

High-throughput

0.489

High

343850

CL12B
C-type lectin domain family 12 member B

1

9

High-throughput

0.489

High

343854

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

1

High-throughput

0.489

High

343843

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

2

High-throughput

0.479

High

343844

RND3
Rho-related GTP-binding protein RhoE

1

7

High-throughput

0.479

High

343845

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

15

High-throughput

0.479

High

343848

PTC1
Protein patched homolog 1

1

8

High-throughput

0.479

High

343839

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

343835

BRAF
Serine/threonine-protein kinase B-raf

1

0

High-throughput

0.458

High

178129

NPC1
NPC intracellular cholesterol transporter 1

1

8

High-throughput

0.445

High

343832

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

11

High-throughput

0.445

High

343849

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

343857

S39A7
Zinc transporter SLC39A7

1

4

High-throughput

0.445

High

343861

RHBG
Ammonium transporter Rh type B

1

1

High-throughput

0.445

High

343863

RHCG
Ammonium transporter Rh type C

1

1

High-throughput

0.445

High

343853

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

222240

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

343858

YLAT2
Y+L amino acid transporter 2

1

0

High-throughput

0.426

High

343851

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

343846

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025