Protein: DB135
Beta-defensin 135 (Defensin, beta 135)

Gene: DB135, DEFB135
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q30KP9

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0045087 - innate immune response
GO:0050829 - defense response to Gram-negative bacterium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

551793

CO6A1

1

1

High-throughput

0.536

High

551861

CO6A2

1

1

High-throughput

0.536

High

582337

ARSA
Arylsulfatase A

1

1

High-throughput

0.536

High

586378

ARSB
Arylsulfatase B

1

1

High-throughput

0.536

High

249046

NRP2
Neuropilin-2

1

0

High-throughput

0.513

High

337263

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

0

High-throughput

0.513

High

541519

FGFR1
Fibroblast growth factor receptor 1

1

0

High-throughput

0.513

High

1181045

CD109
CD109 antigen

1

0

High-throughput

0.513

High

1181046

VWDE
von Willebrand factor D and EGF domain-containing protein

1

0

High-throughput

0.513

High

175375

PLXB2
Plexin-B2

1

2

High-throughput

0.489

High

269673

PLXA2
Plexin-A2

1

3

High-throughput

0.489

High

274879

LRP5
Low-density lipoprotein receptor-related protein 5

1

1

High-throughput

0.489

High

296357

ATRN
Attractin

1

2

High-throughput

0.489

High

907912

PLXA3
Plexin-A3

1

2

High-throughput

0.489

High

922818

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

1

High-throughput

0.489

High

928777

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

1

High-throughput

0.489

High

1116712

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

1

High-throughput

0.489

High

1181043

ATRN1
Attractin-like protein 1

1

1

High-throughput

0.489

High

1181048

AGRV1
Adhesion G-protein coupled receptor V1

1

1

High-throughput

0.489

High

1181051

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

1

High-throughput

0.489

High

1181052

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

1

High-throughput

0.489

High

136611

MANBA
Beta-mannosidase

1

0

High-throughput

0.279

Low

343851

SEM4F
Semaphorin-4F

1

0

High-throughput

0.279

Low

439750

INSR
Insulin receptor

1

0

High-throughput

0.279

Low

720417

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

0

High-throughput

0.279

Low

922440

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.279

Low

977710

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.279

Low

1030417

DIAC
Di-N-acetylchitobiase

1

0

High-throughput

0.279

Low

1036883

SP3
Transcription factor Sp3

1

0

High-throughput

0.279

Low

1127564

FAT1
Protocadherin Fat 1

1

0

High-throughput

0.279

Low

1177219

MICA
MHC class I polypeptide-related sequence A

1

0

High-throughput

0.279

Low

1181039

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

0

High-throughput

0.279

Low

1181040

MKS3
Meckelin

1

0

High-throughput

0.279

Low

1181041

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

0

High-throughput

0.279

Low

1181042

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.279

Low

1181044

SUSD1
Sushi domain-containing protein 1

1

0

High-throughput

0.279

Low

1181047

NLGN2
Neuroligin-2

1

0

High-throughput

0.279

Low

1181049

TECT2
Tectonic-2

1

0

High-throughput

0.279

Low

1181050

TBB1
Tubulin beta-1 chain

1

0

High-throughput

0.279

Low

1181053

CATF
Cathepsin F

1

0

High-throughput

0.279

Low

1181054

CEIP2
Cell surface hyaluronidase CEMIP2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025