Protein: NAMPT
Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin)

Gene: NAMPT
Organism: Homo sapiens
Interactions: 113
UniProt ID: P43490

Gene Ontology (top 5):
GO:0005125 - cytokine activity
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0007165 - signal transduction
GO:0007267 - cell-cell signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849436

NAMPT
Nicotinamide phosphoribosyltransferase

2

1

Small-scale

0.820

High

849437

LEG7
Galectin-7

2

0

High-throughput

0.585

High

241000

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

371405

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

391199

FRIL
Ferritin light chain

1

0

Small-scale

0.549

High

849460

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.536

High

849501

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

563377

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.528

High

733301

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

849456

I13R2
Interleukin-13 receptor subunit alpha-2

1

0

High-throughput

0.513

High

849473

MK15
Mitogen-activated protein kinase 15

1

0

High-throughput

0.513

High

849477

CUL5
Cullin-5

1

0

High-throughput

0.513

High

185500

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

390485

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

830293

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

622732

GGT1
Glutathione hydrolase 1 proenzyme

1

0

Small-scale

0.486

High

709244

AA2AR
Adenosine receptor A2a

1

0

Small-scale

0.486

High

188831

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

411535

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

459242

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

465447

IGF1R
Insulin-like growth factor 1 receptor

1

3

High-throughput

0.479

High

650080

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.479

High

656065

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.479

High

685442

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

High-throughput

0.479

High

720154

UFO
Tyrosine-protein kinase receptor UFO

1

2

High-throughput

0.479

High

731052

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

849440

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.479

High

849447

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

849452

MERTK
Tyrosine-protein kinase Mer

1

3

High-throughput

0.479

High

849458

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.479

High

849468

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.479

High

849474

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

849478

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

849484

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.479

High

849497

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.479

High

187482

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.460

High

728559

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.460

High

259579

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

319496

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

349853

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

353076

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

400444

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

420418

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

484977

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

488739

FURIN
Furin

1

0

High-throughput

0.458

High

536689

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

580605

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

606381

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

692884

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

694844

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

766280

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

849438

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

849439

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

849441

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

849443

CD81
CD81 antigen

1

0

High-throughput

0.458

High

849444

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

849445

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.458

High

849446

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

849450

CREM
cAMP-responsive element modulator

1

0

Small-scale

0.458

High

849451

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

849454

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

849455

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

849459

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

849464

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

849469

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

849476

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

849479

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

849480

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

849485

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

849487

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.458

High

849488

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

849490

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

849494

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

849495

TES
Testin

1

0

High-throughput

0.458

High

168504

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

1

Small-scale

0.457

High

849491

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

680677

CATS
Cathepsin S

1

1

High-throughput

0.437

High

849465

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

849493

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

849496

XPO7
Exportin-7

1

1

High-throughput

0.437

High

849498

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.437

High

849462

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

849499

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

849470

TMM25
Transmembrane protein 25

3

0

High-throughput

0.347

High

849449

IFM3
Interferon-induced transmembrane protein 3

2

0

Small-scale

0.329

High

849466

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

2

0

High-throughput

0.316

High

397585

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

0

Small-scale

0.299

High

723996

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

849471

DAAF8
Dynein axonemal assembly factor 8

1

0

High-throughput

0.279

Low

849472

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.279

Low

849483

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.279

Low

849486

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

849457

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

276078

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.249

Low

352350

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

568378

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

588124

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

767619

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

799788

COIL
Coilin

1

0

High-throughput

0.249

Low

849442

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

849448

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

849453

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

849461

FBX43
F-box only protein 43

1

0

Small-scale

0.249

Low

849463

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low

849467

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

849475

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low

849481

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

849489

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

849500

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

841099

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low

849482

PCFT
Proton-coupled folate transporter

1

0

High-throughput

0.232

Low

849492

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025