Protein: ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)

Gene: ASM3B, SMPDL3B
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q92485

Gene Ontology (top 5):
GO:0004767 - sphingomyelin phosphodiesterase activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006685 - sphingomyelin catabolic process
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

185888

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.614

High

1143074

KPCD1
Serine/threonine-protein kinase D1

2

0

High-throughput

0.547

High

895838

CSRP3
Cysteine and glycine-rich protein 3

1

0

High-throughput

0.513

High

969005

PRS8
26S proteasome regulatory subunit 8

1

0

High-throughput

0.513

High

1154331

CYTM
Cystatin-M

1

0

High-throughput

0.513

High

1250921

ZPBP2
Zona pellucida-binding protein 2

1

0

High-throughput

0.513

High

1333584

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

1363273

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

1180943

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.493

High

1315319

ZDH23
Palmitoyltransferase ZDHHC23

1

1

High-throughput

0.489

High

439805

INSR
Insulin receptor

1

1

Small-scale

0.479

High

1357969

RN138
E3 ubiquitin-protein ligase RNF138

1

1

High-throughput

0.479

High

1363265

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1363271

TRI31
E3 ubiquitin-protein ligase TRIM31

1

1

High-throughput

0.479

High

1041204

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

1363274

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1363277

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.458

High

1363280

WNK2
Serine/threonine-protein kinase WNK2

1

0

High-throughput

0.458

High

337125

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

538645

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.426

High

834998

S19A1
Reduced folate transporter

1

0

High-throughput

0.426

High

912702

CTR2
Cationic amino acid transporter 2

1

0

High-throughput

0.426

High

1234882

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

1353702

MOT10
Monocarboxylate transporter 10

1

0

High-throughput

0.426

High

1363272

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1363276

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

1363278

RHCG
Ammonium transporter Rh type C

1

0

High-throughput

0.426

High

231250

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

724140

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

1108373

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.279

Low

1119518

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.279

Low

1153848

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.279

Low

1353777

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.279

Low

1363266

LEAP2
Liver-expressed antimicrobial peptide 2

1

0

High-throughput

0.279

Low

1363267

CERS2
Ceramide synthase 2

1

0

High-throughput

0.279

Low

1363269

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.279

Low

1363275

CEP15
Centrosomal protein 15

1

0

High-throughput

0.279

Low

1363279

TBD
Tubulin delta chain

1

0

High-throughput

0.279

Low

280751

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.249

Low

478710

HXB5
Homeobox protein Hox-B5

1

0

High-throughput

0.249

Low

1197531

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.249

Low

1197653

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1199809

AGK
Acylglycerol kinase, mitochondrial

1

0

Small-scale

0.249

Low

1338667

T185A
Transmembrane protein 185A

1

0

High-throughput

0.249

Low

1363268

CCNL2
Cyclin-L2

1

0

High-throughput

0.249

Low

1363270

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.249

Low

1214159

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025