Protein: TPST1
Protein-tyrosine sulfotransferase 1 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 1) (TPST-1)

Gene: TPST1
Organism: Homo sapiens
Interactions: 36
UniProt ID: O60507

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005794 - Golgi apparatus
GO:0005796 - Golgi lumen
GO:0005802 - trans-Golgi network
GO:0008476 - protein-tyrosine sulfotransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

250918

TPST2
Protein-tyrosine sulfotransferase 2

2

0

High-throughput

0.736

High

250928

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

2

1

High-throughput

0.628

High

250925

AGRE5
Adhesion G protein-coupled receptor E5

2

0

High-throughput

0.602

High

250927

ACTB
Actin, cytoplasmic 1

2

1

High-throughput

0.601

High

250939

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

1

High-throughput

0.601

High

250948

GINM1
Glycoprotein integral membrane protein 1

2

0

High-throughput

0.585

High

250930

SG2A2
Mammaglobin-A

2

2

High-throughput

0.574

High

250946

GLP3L
Golgi phosphoprotein 3-like

1

3

Small-scale

0.561

High

250947

GOLP3
Golgi phosphoprotein 3

1

3

Small-scale

0.561

High

250921

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

250920

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.493

High

250934

CL12B
C-type lectin domain family 12 member B

1

2

High-throughput

0.489

High

217581

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

250931

SCRB2
Lysosome membrane protein 2

1

2

Small-scale

0.479

High

250932

SELPL
P-selectin glycoprotein ligand 1

1

1

Small-scale

0.479

High

250933

T132D
Transmembrane protein 132D

1

0

Small-scale

0.460

High

250938

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.445

High

250945

TMM59
Transmembrane protein 59

1

1

High-throughput

0.445

High

250950

XCT
Cystine/glutamate transporter

1

6

High-throughput

0.445

High

250926

CCR5
C-C chemokine receptor type 5

1

1

Small-scale

0.437

High

250922

SDC1
Syndecan-1

1

0

High-throughput

0.426

High

250929

TRDN
Triadin

1

0

High-throughput

0.426

High

250935

MTCL3
Microtubule cross-linking factor 3

1

0

High-throughput

0.426

High

250944

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.426

High

189335

STX7
Syntaxin-7

1

1

High-throughput

0.407

High

250924

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

250937

S39A4
Zinc transporter ZIP4

1

3

High-throughput

0.407

High

250940

S7A14
Solute carrier family 7 member 14

1

6

High-throughput

0.407

High

250943

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.407

High

250949

LAT2
Large neutral amino acids transporter small subunit 2

1

6

High-throughput

0.407

High

250923

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.279

Low

250936

FBW10
F-box/WD repeat-containing protein 10

1

0

High-throughput

0.249

Low

250919

DCMC
Malonyl-CoA decarboxylase, mitochondrial

1

0

High-throughput

0.232

Low

250941

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.232

Low

250942

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

High-throughput

0.232

Low

250951

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025