Protein: KCNKG
Potassium channel subfamily K member 16 (2P domain potassium channel Talk-1) (TWIK-related alkaline pH-activated K(+) channel 1) (TALK-1)

Gene: KCNKG, KCNK16
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q96T55

Gene Ontology (top 5):
GO:0005267 - potassium channel activity
GO:0005743 - mitochondrial inner membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1386183

ASTRA
Protein Aster-A

3

0

High-throughput

0.638

High

1403495

SEC62
Translocation protein SEC62

3

0

High-throughput

0.638

High

1403500

ALG9
Alpha-1,2-mannosyltransferase ALG9

3

0

High-throughput

0.638

High

1403506

TMX2
Thioredoxin-related transmembrane protein 2

3

0

High-throughput

0.638

High

1164155

CP51A
Lanosterol 14-alpha demethylase

3

0

High-throughput

0.622

High

1238365

RETST
All-trans-retinol 13,14-reductase

2

1

High-throughput

0.611

High

1403504

DJC16
DnaJ homolog subfamily C member 16

2

3

High-throughput

0.601

High

212599

GPAA1
GPI-anchor transamidase component GPAA1

2

0

High-throughput

0.585

High

215634

EMC8
ER membrane protein complex subunit 8

2

0

High-throughput

0.585

High

1217110

EMC10
ER membrane protein complex subunit 10

2

0

High-throughput

0.585

High

316553

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

2

0

High-throughput

0.576

High

1403505

FND3A
Fibronectin type-III domain-containing protein 3A

2

1

High-throughput

0.558

High

1403494

RMD3
Regulator of microtubule dynamics protein 3

2

2

High-throughput

0.549

High

1293286

LSR
Lipolysis-stimulated lipoprotein receptor

2

0

High-throughput

0.547

High

1275399

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

1

High-throughput

0.536

High

1391910

RN185
E3 ubiquitin-protein ligase RNF185

1

1

High-throughput

0.536

High

1403497

RNF5
E3 ubiquitin-protein ligase RNF5

1

1

High-throughput

0.536

High

1207891

S27A3
Long-chain fatty acid transport protein 3

1

0

High-throughput

0.513

High

1333691

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.513

High

1337642

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

1403499

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.513

High

1403501

SEC12
Guanine nucleotide-exchange factor SEC12

1

0

High-throughput

0.513

High

1352502

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.489

High

604168

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

1403502

DNJB9
DnaJ homolog subfamily B member 9

1

2

High-throughput

0.479

High

399731

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

0

High-throughput

0.458

High

776290

SOX11
Transcription factor SOX-11

1

0

High-throughput

0.458

High

1353080

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

1

0

High-throughput

0.458

High

1403507

POMT1
Protein O-mannosyl-transferase 1

1

0

High-throughput

0.458

High

336273

BRI3
Membrane protein BRI3

1

0

High-throughput

0.426

High

1403503

CCPG1
Cell cycle progression protein 1

4

0

High-throughput

0.360

High

320759

UBXN7
UBX domain-containing protein 7

3

0

High-throughput

0.347

High

1324304

GHDC
GH3 domain-containing protein

3

0

High-throughput

0.347

High

1347639

NPL4
Nuclear protein localization protein 4 homolog

3

0

High-throughput

0.347

High

1403498

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

2

0

High-throughput

0.318

High

733198

OTX1
Homeobox protein OTX1

1

0

High-throughput

0.299

High

1361349

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

426560

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.269

Low

960219

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.269

Low

1403496

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.269

Low

1369981

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.249

Low

1389748

C1GLC
C1GALT1-specific chaperone 1

1

0

High-throughput

0.249

Low

1290884

VPS36
Vacuolar protein-sorting-associated protein 36

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025