Protein: AGFG1
Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein)

Gene: AGFG1
Organism: Homo sapiens
Interactions: 95
UniProt ID: P52594

Gene Ontology (top 5):
GO:0001675 - acrosome assembly
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005096 - GTPase activator activity
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326214

AGFG2
Arf-GAP domain and FG repeat-containing protein 2

2

11

High-throughput

0.811

High

839723

EPS15
Epidermal growth factor receptor substrate 15

3

12

Small-scale

0.662

High

912780

CE170
Centrosomal protein of 170 kDa

1

4

High-throughput

0.618

High

912790

MIB1
E3 ubiquitin-protein ligase MIB1

1

1

High-throughput

0.618

High

912795

SMAP2
Stromal membrane-associated protein 2

1

10

High-throughput

0.618

High

912769

AP2B1
AP-2 complex subunit beta

2

13

High-throughput

0.595

High

363010

EGFR
Epidermal growth factor receptor

2

19

Small-scale

0.584

High

912766

RB11A
Ras-related protein Rab-11A

2

9

High-throughput

0.584

High

907985

VAMP7
Vesicle-associated membrane protein 7

1

1

Small-scale

0.573

High

619629

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.549

High

912764

DPOE2
DNA polymerase epsilon subunit 2

1

0

High-throughput

0.549

High

912804

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.546

High

668537

APC
Adenomatous polyposis coli protein

1

6

High-throughput

0.541

High

912806

TRI54
Tripartite motif-containing protein 54

1

17

High-throughput

0.541

High

912817

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

7

High-throughput

0.536

High

690847

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

912765

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

912772

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

912779

KLH22
Kelch-like protein 22

1

7

High-throughput

0.536

High

912813

NYAP2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

1

3

High-throughput

0.523

High

912801

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.513

High

155652

FCHO1
F-BAR domain only protein 1

1

6

Small-scale

0.501

High

421762

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

912808

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.501

High

912770

EM55
55 kDa erythrocyte membrane protein

1

2

High-throughput

0.489

High

912775

ITSN1
Intersectin-1

1

20

High-throughput

0.481

High

185547

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

172601

XPO1
Exportin-1

1

15

High-throughput

0.479

High

225971

STX6
Syntaxin-6

1

8

High-throughput

0.479

High

241160

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

327203

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.479

High

345552

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

395735

ESR1
Estrogen receptor

1

5

Small-scale

0.479

High

483049

CLCA
Clathrin light chain A

1

5

High-throughput

0.479

High

483311

CLCB
Clathrin light chain B

1

5

High-throughput

0.479

High

541405

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

555969

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

606474

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

641142

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.479

High

660561

IF4B
Eukaryotic translation initiation factor 4B

1

1

High-throughput

0.479

High

694989

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

912763

EPHA5
Ephrin type-A receptor 5

1

13

High-throughput

0.479

High

912767

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

912768

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

912774

SQSTM
Sequestosome-1

1

8

High-throughput

0.479

High

912776

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.479

High

912785

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

912786

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

912787

ATG9A
Autophagy-related protein 9A

1

4

High-throughput

0.479

High

912788

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

912789

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

912793

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

912796

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

912797

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

912798

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

912803

FSD1
Fibronectin type III and SPRY domain-containing protein 1

1

16

High-throughput

0.479

High

912807

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

3

Small-scale

0.479

High

912810

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

912814

TBK1
Serine/threonine-protein kinase TBK1

1

2

High-throughput

0.479

High

912815

UBQL2
Ubiquilin-2

1

5

High-throughput

0.479

High

565245

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

912777

OCLN
Occludin

1

0

High-throughput

0.458

High

912791

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

912805

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

628613

CAP7
Azurocidin

1

1

High-throughput

0.445

High

912794

TBC15
TBC1 domain family member 15

1

3

High-throughput

0.445

High

105618

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

179854

BET1
BET1 homolog

1

7

High-throughput

0.437

High

189473

STX7
Syntaxin-7

1

3

High-throughput

0.437

High

217988

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.437

High

463930

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.437

High

560336

IFM1
Interferon-induced transmembrane protein 1

1

5

High-throughput

0.437

High

588263

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.437

High

630736

RAB4A
Ras-related protein Rab-4A

1

9

High-throughput

0.437

High

648470

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

767756

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

832361

OPRD
Delta-type opioid receptor

1

5

Small-scale

0.437

High

912771

IFM3
Interferon-induced transmembrane protein 3

1

5

High-throughput

0.437

High

912778

DDR2
Discoidin domain-containing receptor 2

1

20

High-throughput

0.437

High

912781

DCA15
DDB1- and CUL4-associated factor 15

1

2

High-throughput

0.437

High

912782

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

912783

FBX42
F-box only protein 42

1

5

High-throughput

0.437

High

912800

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.437

High

912802

RDH12
Retinol dehydrogenase 12

1

1

High-throughput

0.437

High

912809

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

912812

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

7

High-throughput

0.437

High

912816

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.437

High

912773

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

912811

ITM2C
Integral membrane protein 2C

1

3

High-throughput

0.407

High

553390

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

2

0

High-throughput

0.318

High

552931

PIP
Prolactin-inducible protein

2

0

High-throughput

0.313

High

912784

PAQR3
Progestin and adipoQ receptor family member 3

1

0

High-throughput

0.279

Low

912792

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

912799

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

689811

CD27
CD27 antigen

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025