Protein: BUB2
Mitotic check point protein BUB2 (Cell cycle arrest protein BUB2)

Gene: BUB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P26448

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0005737 - cytoplasm
GO:0005816 - spindle pole body
GO:0031030 - negative regulation of septation initiation signaling
GO:0031578 - mitotic spindle orientation checkpoint signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686890

TEM1
Protein TEM1

9

20

Small-scale

0.974

High

686897

BFA1
Mitotic check point protein BFA1

14

0

Small-scale

0.727

High

686888

GIC1
GTPase-interacting component 1

4

1

Small-scale

0.693

High

686902

CDC14
Tyrosine-protein phosphatase CDC14

3

2

Small-scale

0.633

High

686879

NUD1
Protein NUD1

2

4

Small-scale

0.614

High

686876

BUB2
Mitotic check point protein BUB2

1

8

High-throughput

0.575

High

686892

DDI1
DNA damage-inducible protein 1

2

0

High-throughput

0.565

High

686878

XPO1
Exportin-1

1

6

High-throughput

0.536

High

686881

CDC3
Cell division control protein 3

1

1

Small-scale

0.523

High

686906

GIC2
GTPase-interacting component 2

2

1

High-throughput

0.516

High

590555

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

675760

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.500

High

686877

BMH1
Protein BMH1

1

3

High-throughput

0.500

High

686908

HSP42
Heat shock protein 42

1

1

High-throughput

0.500

High

531259

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

686883

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

4

Small-scale

0.479

High

686895

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

366955

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

679430

CDC48
Cell division control protein 48

1

4

High-throughput

0.457

High

365572

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.445

High

445317

CDC31
Cell division control protein 31

1

4

High-throughput

0.445

High

449079

CALM
Calmodulin

1

3

High-throughput

0.445

High

523219

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

544008

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

592055

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

686880

SP110
Spindle pole body component 110

1

4

High-throughput

0.445

High

686884

HSP79
Heat shock protein homolog SSE2

1

5

High-throughput

0.445

High

686889

SPC97
Spindle pole body component SPC97

1

1

High-throughput

0.445

High

686893

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

686894

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

686900

SPC98
Spindle pole body component SPC98

1

1

High-throughput

0.445

High

686901

CNM67
Chaotic nuclear migration protein 67

1

1

High-throughput

0.445

High

686904

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

686907

ESA1
Histone acetyltransferase ESA1

1

2

Small-scale

0.437

High

358132

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

359164

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

364954

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

572529

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.426

High

575901

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

686882

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.426

High

686885

SPC29
Spindle pole component 29

1

0

High-throughput

0.426

High

686887

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.426

High

686891

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.426

High

686896

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

686905

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.426

High

367912

ENO2
Enolase 2

1

2

High-throughput

0.407

High

577270

NSP1
Nucleoporin NSP1

1

1

High-throughput

0.407

High

686903

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

686899

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

686898

YG3O
Uncharacterized protein YGR153W

1

0

High-throughput

0.265

Low

368607

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

626621

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.261

Low

509951

DDI3
Cyanamide hydratase DDI3

1

0

High-throughput

0.251

Low

686886

NIC96
Nucleoporin NIC96

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025