Protein: SPC42
Spindle pole body component SPC42

Gene: SPC42
Organism: Saccharomyces cerevisiae S288C
Interactions: 94
UniProt ID: P36094

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005821 - intermediate layer of spindle pole body
GO:0005823 - central plaque of spindle pole body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

780943

SPC42
Spindle pole body component SPC42

8

0

Small-scale

0.916

High

780975

CNM67
Chaotic nuclear migration protein 67

9

1

Small-scale

0.750

High

735988

SP110
Spindle pole body component 110

11

0

Small-scale

0.724

High

753015

SPC29
Spindle pole component 29

6

0

Small-scale

0.698

High

364472

CDK1
Cyclin-dependent kinase 1

3

1

Small-scale

0.650

High

780977

MPS1
Serine/threonine-protein kinase MPS1

2

1

Small-scale

0.639

High

449113

CALM
Calmodulin

3

0

Small-scale

0.623

High

748823

SWE1
Mitosis inhibitor protein kinase SWE1

2

1

High-throughput

0.619

High

780995

SFI1
Protein SFI1

2

0

Small-scale

0.593

High

755223

NUF2
Kinetochore protein NUF2

2

0

High-throughput

0.587

High

780951

SPC97
Spindle pole body component SPC97

2

1

Small-scale

0.584

High

718936

CGS5
S-phase entry cyclin-5

2

0

Small-scale

0.561

High

780979

CDC14
Tyrosine-protein phosphatase CDC14

2

0

High-throughput

0.547

High

780981

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.547

High

780987

ADY3
Accumulates dyads protein 3

2

1

Small-scale

0.543

High

780954

SAK1
SNF1-activating kinase 1

1

1

High-throughput

0.536

High

780947

MSG5
Tyrosine-protein phosphatase MSG5

1

0

High-throughput

0.513

High

780978

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.513

High

602405

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

780962

TOS3
Serine/threonine-protein kinase TOS3

1

1

High-throughput

0.501

High

780955

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.493

High

747718

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.486

High

780998

MPC70
Sporulation-specific protein 21

1

0

Small-scale

0.486

High

646019

KIN3
Serine/threonine-protein kinase KIN3

1

1

High-throughput

0.481

High

441103

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

656426

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

692334

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

780965

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.480

High

780969

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

416221

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

445333

CDC31
Cell division control protein 31

1

1

Small-scale

0.479

High

581848

SYKC
Lysine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

780948

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

780974

SPC98
Spindle pole body component SPC98

1

1

Small-scale

0.479

High

745467

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.460

High

753061

NIP80
Protein NIP100

1

0

High-throughput

0.460

High

779739

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.460

High

780944

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.460

High

780950

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

0

High-throughput

0.460

High

780952

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

780966

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.460

High

780968

UFD1
Ubiquitin fusion degradation protein 1

1

0

High-throughput

0.460

High

780976

NIS1
Protein NIS1

1

0

High-throughput

0.460

High

780983

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.460

High

780985

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

780992

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

780993

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.460

High

549970

KAR1
Cell division control protein KAR1

1

0

Small-scale

0.458

High

671919

RBSK
Ribokinase

1

0

High-throughput

0.458

High

738526

NDC1
Nucleoporin NDC1

1

0

Small-scale

0.458

High

780957

SS120
Protein SSP120

1

0

High-throughput

0.458

High

780960

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

780964

MPS3
Spindle pole body assembly component MPS3

1

0

Small-scale

0.458

High

780967

NBP1
NAP1-binding protein

1

0

Small-scale

0.458

High

780971

MPS2
Monopolar spindle protein 2

1

0

Small-scale

0.458

High

780973

TBG
Tubulin gamma chain

1

0

Small-scale

0.458

High

780982

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

780988

LAM6
Membrane-anchored lipid-binding protein LAM6

1

0

High-throughput

0.458

High

780991

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.458

High

780994

BBP1
Spindle pole component BBP1

1

0

Small-scale

0.458

High

780996

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

0

High-throughput

0.458

High

780999

YB11B
Transposon Ty1-BL Gag-Pol polyprotein

1

0

High-throughput

0.458

High

781000

RKM4
Ribosomal lysine N-methyltransferase 4

1

0

High-throughput

0.458

High

781002

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.458

High

544470

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

741356

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

780958

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

780990

MPC54
Meiotic plaque component protein 54

1

0

Small-scale

0.438

High

781001

HSH49
Protein HSH49

1

0

High-throughput

0.438

High

780961

EMP47
Protein EMP47

1

1

High-throughput

0.437

High

780997

EMP46
Protein EMP46

1

1

High-throughput

0.437

High

381067

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

523612

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

575924

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

686887

BUB2
Mitotic check point protein BUB2

1

0

High-throughput

0.426

High

726933

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

737399

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.426

High

780946

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.426

High

780949

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

780953

SET5
Histone-lysine N-methyltransferase SET5

1

0

High-throughput

0.426

High

780984

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.426

High

780986

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.426

High

780959

MLP2
Protein MLP2

3

0

Small-scale

0.342

High

734597

NUD1
Protein NUD1

3

0

Small-scale

0.334

High

780956

MBO1
Gamma tubulin complex adapter SPC72

2

0

Small-scale

0.298

High

780970

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.265

Low

781003

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

644681

ATP12
Protein ATP12, mitochondrial

1

0

High-throughput

0.249

Low

780945

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

780972

MTM1
Mitochondrial carrier protein MTM1

1

0

High-throughput

0.249

Low

780980

KIN4
Serine/threonine-protein kinase KIN4

1

0

Small-scale

0.249

Low

780989

ENB1
Siderophore iron transporter ENB1

1

0

High-throughput

0.249

Low

780963

STU2
Protein STU2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025