Protein: ATG5
Autophagy protein 5

Gene: ATG5
Organism: Saccharomyces cerevisiae S288C
Interactions: 45
UniProt ID: Q12380

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy
GO:0005634 - nucleus
GO:0005776 - autophagosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

798012

ATG12
Ubiquitin-like protein ATG12

13

3

Small-scale

0.985

High

1044119

ATG16
Autophagy protein 16

11

0

Small-scale

0.726

High

823112

ATG3
Autophagy-related protein 3

3

2

Small-scale

0.664

High

917214

ATG1
Serine/threonine-protein kinase ATG1

2

2

Small-scale

0.595

High

763551

ATG19
Autophagy-related protein 19

1

1

Small-scale

0.561

High

722371

XPO1
Exportin-1

1

1

High-throughput

0.536

High

725905

CYS3
Cystathionine gamma-lyase

1

0

High-throughput

0.513

High

796760

RXT2
Transcriptional regulatory protein RXT2

1

0

High-throughput

0.513

High

557047

AAKG
5'-AMP-activated protein kinase subunit gamma

1

1

High-throughput

0.508

High

795606

ATG8
Autophagy-related protein 8

1

9

Small-scale

0.501

High

806202

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

1

Small-scale

0.501

High

850432

ATG18
Autophagy-related protein 18

1

2

Small-scale

0.501

High

1084719

ATG34
Autophagy-related protein 34

1

1

Small-scale

0.501

High

359086

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.500

High

359544

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.500

High

408598

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

1

High-throughput

0.500

High

416493

HXKA
Hexokinase-1

1

2

High-throughput

0.500

High

416580

HXKB
Hexokinase-2

1

2

High-throughput

0.500

High

538354

PYC1
Pyruvate carboxylase 1

1

2

High-throughput

0.500

High

607801

HXKG
Glucokinase-1

1

2

High-throughput

0.500

High

626931

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.500

High

454769

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

High-throughput

0.486

High

850929

CHA4
Activatory protein CHA4

1

0

High-throughput

0.486

High

408369

GAL1
Galactokinase

1

0

High-throughput

0.479

High

452997

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.479

High

572670

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

597311

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.479

High

797199

ATG14
Autophagy-related protein 14

1

0

Small-scale

0.458

High

1054983

ATG17
Autophagy-related protein 17

1

0

Small-scale

0.458

High

1056292

ATG13
Autophagy-related protein 13

1

0

Small-scale

0.458

High

1084292

ATG29
Autophagy-related protein 29

1

0

Small-scale

0.458

High

386921

TBB
Tubulin beta chain

1

5

High-throughput

0.457

High

546815

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742723

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

820170

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

525607

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

727417

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

470662

ERG20
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.279

Low

808726

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.279

Low

432374

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.261

Low

439175

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.261

Low

740703

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.261

Low

746320

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

917034

ARO8
Aromatic/aminoadipate aminotransferase 1

1

0

High-throughput

0.261

Low

510916

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025